Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 3586885..3587246 Replicon chromosome
Accession NZ_CP090523
Organism Xanthomonas citri pv. glycines strain ICMP5732

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag LMJ37_RS15645 Protein ID WP_005914328.1
Coordinates 3586885..3587019 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag LMJ37_RS15650 Protein ID WP_003486606.1
Coordinates 3587094..3587246 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LMJ37_RS15625 (LMJ37_15625) 3582036..3583727 - 1692 WP_029829576.1 M28 family metallopeptidase -
LMJ37_RS15630 (LMJ37_15630) 3583919..3584863 - 945 WP_026007158.1 MBL fold metallo-hydrolase -
LMJ37_RS15635 (LMJ37_15635) 3584992..3586281 - 1290 WP_016850773.1 tryptophan--tRNA ligase -
LMJ37_RS15640 (LMJ37_15640) 3586449..3586658 - 210 WP_003486601.1 CsbD family protein -
LMJ37_RS15645 (LMJ37_15645) 3586885..3587019 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
LMJ37_RS15650 (LMJ37_15650) 3587094..3587246 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
LMJ37_RS15655 (LMJ37_15655) 3587353..3588276 - 924 WP_003486608.1 arginase -
LMJ37_RS15660 (LMJ37_15660) 3588597..3589049 + 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
LMJ37_RS15665 (LMJ37_15665) 3589113..3589472 + 360 WP_003486613.1 hypothetical protein -
LMJ37_RS15670 (LMJ37_15670) 3589569..3590486 + 918 WP_016850774.1 hypothetical protein -
LMJ37_RS15675 (LMJ37_15675) 3590483..3591025 + 543 WP_003486615.1 GTPase -
LMJ37_RS15680 (LMJ37_15680) 3591463..3592146 + 684 WP_011052674.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T231007 WP_005914328.1 NZ_CP090523:c3587019-3586885 [Xanthomonas citri pv. glycines]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T231007 NZ_CP125806:1570407-1570697 [Pasteurella multocida]
ATGAGTAAAAAAGTAGAATTAAAACCATTTGATATTGCTGAATACCTAGATAGTGAAGAAATGATTGCGGCATATTTAAG
TGAAATTTTAGAAACAGGTGACACTAATGAATTTATTTCTGCGCTAGGTGATGTCGCAAGAGCGAGAGGAATGACGGAGT
TAGCGGCAAAAACAGGATTAGGAAGAGAAAGTCTCTATAAAACATTATCACACGGAAGTAAGCCGCGTTTTGATACTATA
ATGAAAATTACGCAAGCACTAGGTATTAAACTTGTCCCAACGCATATCTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT231007 WP_003486606.1 NZ_CP090523:c3587246-3587094 [Xanthomonas citri pv. glycines]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT231007 NZ_CP125806:1570096-1570410 [Pasteurella multocida]
ATGCTCGATATAATTGAAACAACAGTATTTAATAAATGGCTTAAAGAGCTAAAGGATTTGTCGGCTAAAGCGGCTATTCT
TGCACGTATTAGTCGCGCTAAAAGTGGTAATTTTGGTGACCATAAATCAGTTGGTGATGGTTTGTATGAAATGCGAATAA
TGAAAGGAGCTGGTTATAGGGTTTATTATGCACAATACAAAGATGTAACCTATTTGCTAATTTGTGGCGGTGATAAATCT
ACTCAGAAAGCAGATATCGCTAAAGCAAAAGCATTATGGGAAGAGATTAAGCAGAAAGAGGAGATAAATGTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References