Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PumA-relB/COG3657-DUF971 |
| Location | 1385210..1385815 | Replicon | chromosome |
| Accession | NZ_CP090514 | ||
| Organism | Xylella fastidiosa subsp. fastidiosa strain Riv13 | ||
Toxin (Protein)
| Gene name | PumA | Uniprot ID | B2I5N3 |
| Locus tag | LZ753_RS06255 | Protein ID | WP_004089252.1 |
| Coordinates | 1385210..1385506 (+) | Length | 99 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | LZ753_RS06260 | Protein ID | WP_004089254.1 |
| Coordinates | 1385510..1385815 (+) | Length | 102 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LZ753_RS06230 (LZ753_06230) | 1380375..1381352 | + | 978 | WP_004087353.1 | hypothetical protein | - |
| LZ753_RS06235 (LZ753_06235) | 1381611..1382057 | + | 447 | WP_004087355.1 | hypothetical protein | - |
| LZ753_RS06240 (LZ753_06240) | 1382161..1383405 | - | 1245 | WP_011097983.1 | tail fiber protein | - |
| LZ753_RS06245 (LZ753_06245) | 1383409..1383969 | - | 561 | WP_011097869.1 | DUF2612 domain-containing protein | - |
| LZ753_RS06250 (LZ753_06250) | 1383966..1385111 | - | 1146 | WP_011097984.1 | baseplate J/gp47 family protein | - |
| LZ753_RS06255 (LZ753_06255) | 1385210..1385506 | + | 297 | WP_004089252.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LZ753_RS06260 (LZ753_06260) | 1385510..1385815 | + | 306 | WP_004089254.1 | putative addiction module antidote protein | Antitoxin |
| LZ753_RS06265 (LZ753_06265) | 1385826..1386179 | - | 354 | WP_234502177.1 | hypothetical protein | - |
| LZ753_RS06270 (LZ753_06270) | 1386176..1386817 | - | 642 | WP_012382583.1 | Gp138 family membrane-puncturing spike protein | - |
| LZ753_RS06275 (LZ753_06275) | 1386814..1387644 | - | 831 | WP_012382584.1 | hypothetical protein | - |
| LZ753_RS06280 (LZ753_06280) | 1387641..1387958 | - | 318 | WP_011097873.1 | hypothetical protein | - |
| LZ753_RS06285 (LZ753_06285) | 1387958..1388728 | - | 771 | WP_004090769.1 | hypothetical protein | - |
| LZ753_RS06290 (LZ753_06290) | 1388839..1389066 | + | 228 | WP_004091377.1 | DUF6290 family protein | - |
| LZ753_RS06295 (LZ753_06295) | 1389050..1389316 | + | 267 | WP_011097988.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1382161..1425075 | 42914 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 99 a.a. Molecular weight: 10790.57 Da Isoelectric Point: 10.0509
>T230989 WP_004089252.1 NZ_CP090514:1385210-1385506 [Xylella fastidiosa subsp. fastidiosa]
MVELIKTSTFDAWINSLRDRKAAARIQARLDRLALGNPGDVKPVGAGISEMRIDHGPGYRIYFMKHGAVLILLLCGGDKS
SQVRDIEQAKALAALWKD
MVELIKTSTFDAWINSLRDRKAAARIQARLDRLALGNPGDVKPVGAGISEMRIDHGPGYRIYFMKHGAVLILLLCGGDKS
SQVRDIEQAKALAALWKD
Download Length: 297 bp
>T230989 NZ_CP125781:948250-948660 [Trabulsiella odontotermitis]
GTGGTCCTGTGGCAATCTGATCTTCGCGTCTCGTGGCGCTCGCAATGGATTTCTCTGCTGCTGCATGGTGTTGTGGCGGC
GGTTGTATTGCTGATGCCCTGGCCTCTCAGCTATACCCCGTTATGGCTGTTGCTGCTGTCGCTGGTGGTGTTCGACAGCG
TTCGCAGCCAGCGGCGGATTAACGCCCGACAGGGTGAAATCAAACTGCTGATGGACGGGCGGCTTCGCTGGCAGAACCAG
GAGTGGGAAATTCTCGGCACACCGTGGATGCTGAGCATCGGGATGCTGCTGCGTTTGCGTCGGGTGGGGCAACGCCGCGG
CCAGCATTTATGGCTGGCGGCAGACAGTATGGATAGCAGGGAGTGGCGCGATTTGCGCCGGGTCATTTTGCAAAGACCGG
CGCAGGAGTAG
GTGGTCCTGTGGCAATCTGATCTTCGCGTCTCGTGGCGCTCGCAATGGATTTCTCTGCTGCTGCATGGTGTTGTGGCGGC
GGTTGTATTGCTGATGCCCTGGCCTCTCAGCTATACCCCGTTATGGCTGTTGCTGCTGTCGCTGGTGGTGTTCGACAGCG
TTCGCAGCCAGCGGCGGATTAACGCCCGACAGGGTGAAATCAAACTGCTGATGGACGGGCGGCTTCGCTGGCAGAACCAG
GAGTGGGAAATTCTCGGCACACCGTGGATGCTGAGCATCGGGATGCTGCTGCGTTTGCGTCGGGTGGGGCAACGCCGCGG
CCAGCATTTATGGCTGGCGGCAGACAGTATGGATAGCAGGGAGTGGCGCGATTTGCGCCGGGTCATTTTGCAAAGACCGG
CGCAGGAGTAG
Antitoxin
Download Length: 102 a.a. Molecular weight: 10983.37 Da Isoelectric Point: 5.0941
>AT230989 WP_004089254.1 NZ_CP090514:1385510-1385815 [Xylella fastidiosa subsp. fastidiosa]
MNNETFSRYDTADYLKTEEDIAAYMEAVMEEGGRDNPAFIARALGAVARARNLSQLARDVGMSRQGLDKALSNDGNPSFS
TILKVAKALGLRMSFTPSSMS
MNNETFSRYDTADYLKTEEDIAAYMEAVMEEGGRDNPAFIARALGAVARARNLSQLARDVGMSRQGLDKALSNDGNPSFS
TILKVAKALGLRMSFTPSSMS
Download Length: 306 bp
>AT230989 NZ_CP125781:948003-948269 [Trabulsiella odontotermitis]
ATGGACATTAATAATAAATCTCGTATCCATTGGGCATGCCGCCGCGGTATGCGCGAACTTGATATCTCTATCATGCCGTT
TTTTGAGCATGAGTACGATACGCTGACTGACGACGACAAGCGCCTTTTTATTCGTCTGCTGGAGTGCGACGATCCGGATC
TGTTTAACTGGCTGATGAATCACGGAAAACCCGACGATGCCGGGTTACAGCGCATGGTGCTCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA
ATGGACATTAATAATAAATCTCGTATCCATTGGGCATGCCGCCGCGGTATGCGCGAACTTGATATCTCTATCATGCCGTT
TTTTGAGCATGAGTACGATACGCTGACTGACGACGACAAGCGCCTTTTTATTCGTCTGCTGGAGTGCGACGATCCGGATC
TGTTTAACTGGCTGATGAATCACGGAAAACCCGACGATGCCGGGTTACAGCGCATGGTGCTCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|