Detailed information of TA system TA230982

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-StbC
• Location: 2454088..2454771
• Replicon: chromosome
• Accession: NZ_CP090513
• Organism: Xylella fastidiosa subsp. multiplex strain Red Oak 8

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: LZ751_RS10860
• Protein ID: WP_004086858.1
• Coordinates: 2454088..2454516 (-)
• Length: 143 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: LZ751_RS10865
• Protein ID: WP_004086856.1
• Coordinates: 2454517..2454771 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LZ751_RS10830 (LZ751_10830)	2450642..2451403	-	762	WP_004085598.1	Bax inhibitor-1/YccA family protein	-
LZ751_RS10855 (LZ751_10855)	2452604..2453998	+	1395	WP_012338158.1	hypothetical protein	-
LZ751_RS10860 (LZ751_10860)	2454088..2454516	-	429	WP_004086858.1	type II toxin-antitoxin system VapC family toxin	Toxin
LZ751_RS10865 (LZ751_10865)	2454517..2454771	-	255	WP_004086856.1	hypothetical protein	Antitoxin
LZ751_RS10870 (LZ751_10870)	2454896..2455438	+	543	WP_012338159.1	hypothetical protein	-
LZ751_RS10875 (LZ751_10875)	2455759..2456132	-	374	Protein_2129	DUF596 domain-containing protein	-
LZ751_RS10880 (LZ751_10880)	2456144..2456449	-	306	WP_228762248.1	DUF769 domain-containing protein	-
LZ751_RS10885 (LZ751_10885)	2456648..2457069	-	422	Protein_2131	DUF596 domain-containing protein	-
LZ751_RS10890 (LZ751_10890)	2457050..2457307	-	258	WP_021358680.1	hemagglutinin	-
LZ751_RS10895 (LZ751_10895)	2457581..2457964	-	384	WP_004086848.1	DUF596 domain-containing protein	-
LZ751_RS10900 (LZ751_10900)	2457969..2459006	-	1038	WP_012338161.1	DUF769 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-124)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 143 a.a.
• Molecular weight: 15641.79 Da
• Isoelectric Point: 5.1634

>T230982 WP_004086858.1 NZ_CP090513:c2454516-2454088 [Xylella fastidiosa subsp. multiplex]
MIVLDTNVVSEAMKPEPDAAVRTWLNEQMSVTLYLSSVTLSELLFGIAVLPTSKRKDMLARTLDGLLDLFNERVLPFDTD
AARHYAELAVKARNNGRGFPTPDGYIAAIAASRGYIVASRDTSAYESSGVQVINPWQYSKQT

Nucleotide

• Length: 429 bp

>T230982 NZ_CP125762:2212616-2212792 [Bacillus subtilis]
GTGCTTGAGAAAATGGGTATCGTAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACGTATACGCCGATGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9601.95 Da
• Isoelectric Point: 6.4732

>AT230982 WP_004086856.1 NZ_CP090513:c2454771-2454517 [Xylella fastidiosa subsp. multiplex]
MAMLTVRNLPDEVHRALRVRAATHGRSTEAEVREILTNIVKPDERVRIGDALAILGREIGLNNEDFTTFDKVRDKTQAEP
MRFE

Nucleotide

• Length: 255 bp

>AT230982 NZ_CP125762:c2212675-2212575 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTACGATACCCATTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT