Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | pasABC/RelE-HTH |
| Location | 1423424..1423901 | Replicon | chromosome |
| Accession | NZ_CP090511 | ||
| Organism | Xylella fastidiosa subsp. multiplex strain Oak 35874 | ||
Toxin (Protein)
| Gene name | pasB | Uniprot ID | - |
| Locus tag | LZ754_RS06570 | Protein ID | WP_004087087.1 |
| Coordinates | 1423635..1423901 (+) | Length | 89 a.a. |
Antitoxin (Protein)
| Gene name | pasA | Uniprot ID | A0A7G7TPD2 |
| Locus tag | LZ754_RS06565 | Protein ID | WP_004091377.1 |
| Coordinates | 1423424..1423651 (+) | Length | 76 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LZ754_RS06525 (LZ754_06525) | 1418552..1419697 | - | 1146 | WP_234499695.1 | baseplate J/gp47 family protein | - |
| LZ754_RS06530 (LZ754_06530) | 1419796..1420092 | + | 297 | WP_004089252.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| LZ754_RS06535 (LZ754_06535) | 1420096..1420401 | + | 306 | WP_038211623.1 | putative addiction module antidote protein | - |
| LZ754_RS06540 (LZ754_06540) | 1420412..1420765 | - | 354 | WP_071870016.1 | hypothetical protein | - |
| LZ754_RS06545 (LZ754_06545) | 1420762..1421322 | - | 561 | WP_234499696.1 | Gp138 family membrane-puncturing spike protein | - |
| LZ754_RS06550 (LZ754_06550) | 1421399..1422229 | - | 831 | WP_027700631.1 | hypothetical protein | - |
| LZ754_RS06555 (LZ754_06555) | 1422226..1422543 | - | 318 | WP_012382585.1 | hypothetical protein | - |
| LZ754_RS06560 (LZ754_06560) | 1422543..1423313 | - | 771 | WP_234499697.1 | hypothetical protein | - |
| LZ754_RS06565 (LZ754_06565) | 1423424..1423651 | + | 228 | WP_004091377.1 | DUF6290 family protein | Antitoxin |
| LZ754_RS06570 (LZ754_06570) | 1423635..1423901 | + | 267 | WP_004087087.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LZ754_RS06575 (LZ754_06575) | 1423912..1424823 | - | 912 | WP_234499698.1 | hypothetical protein | - |
| LZ754_RS06580 (LZ754_06580) | 1424796..1425800 | - | 1005 | WP_234499699.1 | phage tail tape measure protein | - |
| LZ754_RS06585 (LZ754_06585) | 1425948..1426190 | - | 243 | WP_234499994.1 | putative phage tail assembly chaperone | - |
| LZ754_RS06590 (LZ754_06590) | 1426208..1426546 | - | 339 | WP_140161927.1 | hypothetical protein | - |
| LZ754_RS06595 (LZ754_06595) | 1426556..1427038 | - | 483 | WP_038230283.1 | hypothetical protein | - |
| LZ754_RS06600 (LZ754_06600) | 1427048..1428256 | - | 1209 | WP_140160989.1 | DUF2213 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 89 a.a. Molecular weight: 10207.80 Da Isoelectric Point: 10.3398
>T230965 WP_004087087.1 NZ_CP090511:1423635-1423901 [Xylella fastidiosa subsp. multiplex]
MAWTIDYTDTAKQQLRKLDKHMARRIVDFMDERIAGLENPRSSGKALTGPLGGFWRYRVGDFRVVCDIQDSVLRVLVVRV
GHRGEIYR
MAWTIDYTDTAKQQLRKLDKHMARRIVDFMDERIAGLENPRSSGKALTGPLGGFWRYRVGDFRVVCDIQDSVLRVLVVRV
GHRGEIYR
Download Length: 267 bp
>T230965 NZ_CP125734:4019830-4020048 [Klebsiella pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACTTCTGTCTGGAAATTTATCCGCTAA
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACTTCTGTCTGGAAATTTATCCGCTAA
Antitoxin
Download Length: 76 a.a. Molecular weight: 8615.63 Da Isoelectric Point: 5.0958
>AT230965 WP_004091377.1 NZ_CP090511:1423424-1423651 [Xylella fastidiosa subsp. multiplex]
MATSIRLSPEMEQRLNSLASHTGRTKAYYLREIIEHGIEEMEDYYLAADVLERVRHGQEQVHSAADVRKTLGLDD
MATSIRLSPEMEQRLNSLASHTGRTKAYYLREIIEHGIEEMEDYYLAADVLERVRHGQEQVHSAADVRKTLGLDD
Download Length: 228 bp
>AT230965 NZ_CP125734:4019429-4019803 [Klebsiella pneumoniae]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACGTCGGCTGTCAATCTCCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCTCTTAATTATAAAATTAAGTATGCAGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACTTTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAACCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAACCCGGCCAGTCTATCGTGTTAG
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACGTCGGCTGTCAATCTCCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCTCTTAATTATAAAATTAAGTATGCAGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACTTTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAACCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAACCCGGCCAGTCTATCGTGTTAG
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|