Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 1052095..1052849 Replicon chromosome
Accession NZ_CP090511
Organism Xylella fastidiosa subsp. multiplex strain Oak 35874

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag LZ754_RS04620 Protein ID WP_021358673.1
Coordinates 1052095..1052574 (-) Length 160 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag LZ754_RS04625 Protein ID WP_004085396.1
Coordinates 1052577..1052849 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZ754_RS04610 (LZ754_04610) 1048948..1049754 + 807 WP_038211175.1 oxidoreductase -
LZ754_RS04615 (LZ754_04615) 1049894..1051759 + 1866 WP_140161022.1 DUF5710 domain-containing protein -
LZ754_RS04620 (LZ754_04620) 1052095..1052574 - 480 WP_021358673.1 GNAT family N-acetyltransferase Toxin
LZ754_RS04625 (LZ754_04625) 1052577..1052849 - 273 WP_004085396.1 DUF1778 domain-containing protein Antitoxin
LZ754_RS04630 (LZ754_04630) 1053201..1054106 - 906 WP_004085395.1 AEC family transporter -
LZ754_RS04635 (LZ754_04635) 1054222..1054840 + 619 Protein_903 IS607 family transposase -
LZ754_RS12295 1055068..1056096 + 1029 WP_267963002.1 glycoside hydrolase family 3 N-terminal domain-containing protein -
LZ754_RS12300 1056096..1057100 + 1005 WP_267963003.1 glycoside hydrolase family 3 N-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(33-146)

Antitoxin

Vibrio phage ICP1, Orf50

(3-85)


Sequences

Toxin        


Download         Length: 160 a.a.        Molecular weight: 17645.42 Da        Isoelectric Point: 9.9283

>T230963 WP_021358673.1 NZ_CP090511:c1052574-1052095 [Xylella fastidiosa subsp. multiplex]
MQISTPHSLTAAHRLDEFNCGEPSLDDWLKRRALTNHLNGASRTFVVIDANQYVLGYYALAAGAVAHQEATRAIRRNMPD
PVPVMVLGRLAVDTRAQGIKLGAALLKDTVTRVQSIAENAGVRALVVHALNERAKQFYEYYGFRASPMHLMTLMLPIKF

Download         Length: 480 bp

>T230963 NZ_CP125734:c3196319-3196143 [Klebsiella pneumoniae]
GTGAAGCAAAGCGAGTTGAGGCGTTGGCTTGCAGCTCAAGGGGCAGAATTTAAAGATGGTACTAACCACTTGAAAATCTA
TCTCAACGGCAAGCAAACGGTAATGCCGAGACATCCGGGGAAGGAAATACCGGAACCGCTGAGGAAGGCAATTCTTAAGC
AACTCGGCATCAAATAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10264.77 Da        Isoelectric Point: 5.0488

>AT230963 WP_004085396.1 NZ_CP090511:c1052849-1052577 [Xylella fastidiosa subsp. multiplex]
MRDASINLRAMPEQRDLIDQAANLLGKNRSDFMLEAACERAKAIILDQVFFNLDEERFRQFTVLLNAPQDTNPGLNRLMA
IKAPWSISNT

Download         Length: 273 bp

>AT230963 NZ_CP125734:c3196095-3195688 [Klebsiella pneumoniae]
ATGCGATACCCGGTAATTTTTGAGCATGACGAAACCGGCTGGGCGGTATTCTTTCCGGATATCCCAGAGGCAATGACGGG
AGGAGAGACCAGGGAGGAGGCGTTAGAAATGGCGCAAGATGCCCTGGTGACGGCGTTTGATTTTTACTTTGACGACCGCC
GGGAGATTCCCGCTCCATCAGCAGAAGGTGATGCGTTTGTTGAGGTTCCGGCCAGCGTGGCAGCTAAAGTATTGCTGTTA
AACCGTCTGGTCAGCACCAACACTAGCAATGCTGATCTCGCCCGCATGATTAACACGCGCCCACAGGAAGTGCAGCGCAT
CGTGTCTCTTGGTCACAGCACCAAAATCGATACGATCCAAAAAGCGCTATCAGCGTTGGGGCAAAAGATGGAAATTGTCG
TCCACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References