Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2501377..2502060 Replicon chromosome
Accession NZ_CP090510
Organism Xylella fastidiosa subsp. multiplex strain LA-Y3C

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LZ759_RS11050 Protein ID WP_004086858.1
Coordinates 2501377..2501805 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LZ759_RS11055 Protein ID WP_004086856.1
Coordinates 2501806..2502060 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZ759_RS11020 (LZ759_11020) 2497931..2498692 - 762 WP_004085598.1 Bax inhibitor-1/YccA family protein -
LZ759_RS11045 (LZ759_11045) 2499893..2501287 + 1395 WP_234545787.1 hypothetical protein -
LZ759_RS11050 (LZ759_11050) 2501377..2501805 - 429 WP_004086858.1 type II toxin-antitoxin system VapC family toxin Toxin
LZ759_RS11055 (LZ759_11055) 2501806..2502060 - 255 WP_004086856.1 hypothetical protein Antitoxin
LZ759_RS11060 (LZ759_11060) 2502185..2502727 + 543 WP_071870032.1 hypothetical protein -
LZ759_RS11065 (LZ759_11065) 2503048..2503421 - 374 Protein_2164 DUF596 domain-containing protein -
LZ759_RS11070 (LZ759_11070) 2503433..2503738 - 306 WP_228762248.1 DUF769 domain-containing protein -
LZ759_RS11075 (LZ759_11075) 2503937..2504329 - 393 WP_038211775.1 DUF596 domain-containing protein -
LZ759_RS11080 (LZ759_11080) 2504340..2504597 - 258 WP_021358680.1 hemagglutinin -
LZ759_RS11085 (LZ759_11085) 2504871..2505254 - 384 WP_004086848.1 DUF596 domain-containing protein -
LZ759_RS11090 (LZ759_11090) 2505259..2506296 - 1038 WP_140189438.1 DUF769 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15641.79 Da        Isoelectric Point: 5.1634

>T230960 WP_004086858.1 NZ_CP090510:c2501805-2501377 [Xylella fastidiosa subsp. multiplex]
MIVLDTNVVSEAMKPEPDAAVRTWLNEQMSVTLYLSSVTLSELLFGIAVLPTSKRKDMLARTLDGLLDLFNERVLPFDTD
AARHYAELAVKARNNGRGFPTPDGYIAAIAASRGYIVASRDTSAYESSGVQVINPWQYSKQT

Download         Length: 429 bp

>T230960 NZ_CP125734:781224-781634 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAGATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9601.95 Da        Isoelectric Point: 6.4732

>AT230960 WP_004086856.1 NZ_CP090510:c2502060-2501806 [Xylella fastidiosa subsp. multiplex]
MAMLTVRNLPDEVHRALRVRAATHGRSTEAEVREILTNIVKPDERVRIGDALAILGREIGLNNEDFTTFDKVRDKTQAEP
MRFE

Download         Length: 255 bp

>AT230960 NZ_CP125734:780977-781243 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References