Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | pasABC/RelE-HTH |
| Location | 1377475..1377952 | Replicon | chromosome |
| Accession | NZ_CP090510 | ||
| Organism | Xylella fastidiosa subsp. multiplex strain LA-Y3C | ||
Toxin (Protein)
| Gene name | pasB | Uniprot ID | - |
| Locus tag | LZ759_RS06070 | Protein ID | WP_004087087.1 |
| Coordinates | 1377686..1377952 (+) | Length | 89 a.a. |
Antitoxin (Protein)
| Gene name | pasA | Uniprot ID | A0A7G7TPD2 |
| Locus tag | LZ759_RS06065 | Protein ID | WP_004091377.1 |
| Coordinates | 1377475..1377702 (+) | Length | 76 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LZ759_RS06025 (LZ759_06025) | 1372566..1373711 | - | 1146 | WP_234545657.1 | baseplate J/gp47 family protein | - |
| LZ759_RS06030 (LZ759_06030) | 1373814..1374110 | + | 297 | WP_004085590.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| LZ759_RS06035 (LZ759_06035) | 1374113..1374406 | + | 294 | WP_004085592.1 | putative addiction module antidote protein | - |
| LZ759_RS06040 (LZ759_06040) | 1374462..1374815 | - | 354 | WP_027700632.1 | hypothetical protein | - |
| LZ759_RS06045 (LZ759_06045) | 1374812..1375453 | - | 642 | WP_012382583.1 | Gp138 family membrane-puncturing spike protein | - |
| LZ759_RS06050 (LZ759_06050) | 1375450..1376280 | - | 831 | WP_128734736.1 | hypothetical protein | - |
| LZ759_RS06055 (LZ759_06055) | 1376277..1376594 | - | 318 | WP_012382585.1 | hypothetical protein | - |
| LZ759_RS06060 (LZ759_06060) | 1376594..1377364 | - | 771 | WP_140160955.1 | hypothetical protein | - |
| LZ759_RS06065 (LZ759_06065) | 1377475..1377702 | + | 228 | WP_004091377.1 | DUF6290 family protein | Antitoxin |
| LZ759_RS06070 (LZ759_06070) | 1377686..1377952 | + | 267 | WP_004087087.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LZ759_RS06075 (LZ759_06075) | 1377963..1379603 | - | 1641 | WP_234545659.1 | phage tail tape measure protein | - |
| LZ759_RS06080 (LZ759_06080) | 1379809..1379973 | - | 165 | WP_014607750.1 | hypothetical protein | - |
| LZ759_RS06085 (LZ759_06085) | 1380000..1380425 | - | 426 | WP_234545923.1 | putative phage tail assembly chaperone | - |
| LZ759_RS06090 (LZ759_06090) | 1380479..1380817 | - | 339 | WP_140160957.1 | hypothetical protein | - |
| LZ759_RS06095 (LZ759_06095) | 1380827..1381309 | - | 483 | WP_140189638.1 | hypothetical protein | - |
| LZ759_RS06100 (LZ759_06100) | 1381319..1382527 | - | 1209 | WP_194957579.1 | DUF2213 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1370761..1436093 | 65332 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 89 a.a. Molecular weight: 10207.80 Da Isoelectric Point: 10.3398
>T230958 WP_004087087.1 NZ_CP090510:1377686-1377952 [Xylella fastidiosa subsp. multiplex]
MAWTIDYTDTAKQQLRKLDKHMARRIVDFMDERIAGLENPRSSGKALTGPLGGFWRYRVGDFRVVCDIQDSVLRVLVVRV
GHRGEIYR
MAWTIDYTDTAKQQLRKLDKHMARRIVDFMDERIAGLENPRSSGKALTGPLGGFWRYRVGDFRVVCDIQDSVLRVLVVRV
GHRGEIYR
Download Length: 267 bp
>T230958 NZ_CP125734:358000-358347 [Klebsiella pneumoniae]
ATGTGGGATGTAGAAACGACGGATACGTTTGATACCTGGTTCGAATTACAAAGTAGAGCTTTAAAAGAGGATATGTTGGC
CACGATGCTCATCCTGTCTGAGTTTGCTCCGCAGCTTGGGCGCCCGTATGTTGATACGGTGAAAGATTCAACGTTTCAGA
ATATGAAAGAACTGCGGGTTCAGCATCATGGGCTCCCCATCCGCGCCTTTTTTGCTTTTGATCCTCTGCGGAAAGCTATC
GTTTTATGTGCGGACAATAAGGATGGCATGAATGAGAAACGTTTTTACAAAGAGATGATTACTCTGGCTGACAGAGAATT
CAGCCAACACCTGACTAAGGAGCGATAA
ATGTGGGATGTAGAAACGACGGATACGTTTGATACCTGGTTCGAATTACAAAGTAGAGCTTTAAAAGAGGATATGTTGGC
CACGATGCTCATCCTGTCTGAGTTTGCTCCGCAGCTTGGGCGCCCGTATGTTGATACGGTGAAAGATTCAACGTTTCAGA
ATATGAAAGAACTGCGGGTTCAGCATCATGGGCTCCCCATCCGCGCCTTTTTTGCTTTTGATCCTCTGCGGAAAGCTATC
GTTTTATGTGCGGACAATAAGGATGGCATGAATGAGAAACGTTTTTACAAAGAGATGATTACTCTGGCTGACAGAGAATT
CAGCCAACACCTGACTAAGGAGCGATAA
Antitoxin
Download Length: 76 a.a. Molecular weight: 8615.63 Da Isoelectric Point: 5.0958
>AT230958 WP_004091377.1 NZ_CP090510:1377475-1377702 [Xylella fastidiosa subsp. multiplex]
MATSIRLSPEMEQRLNSLASHTGRTKAYYLREIIEHGIEEMEDYYLAADVLERVRHGQEQVHSAADVRKTLGLDD
MATSIRLSPEMEQRLNSLASHTGRTKAYYLREIIEHGIEEMEDYYLAADVLERVRHGQEQVHSAADVRKTLGLDD
Download Length: 228 bp
>AT230958 NZ_CP125734:358347-358646 [Klebsiella pneumoniae]
ATGGCCACGCTAAAAGAACTCATGGCGAAACAGAGTCCTGATAGCCAGCAGCGTATTGCAGCGAAAGCGGCAGAGATACG
CCAGTCTGTCGCTTTAAACTTGCTTCGAGAAGAGTTGCAAATGTCGCAAACAGAGATGGCTGCGGCTATGGGGGTAAAGC
AGCCAACGATCGCTAAAATGGAACAGGCTGATAACGACCCTCGGCTTTCGACCCTAAAACGCTACATTGCGGCATTGGGG
GGAGAACTCAGTATAAATGTCACATTGCCGACTGGAAAAAAAGTCTCGTTTAATTTGTGA
ATGGCCACGCTAAAAGAACTCATGGCGAAACAGAGTCCTGATAGCCAGCAGCGTATTGCAGCGAAAGCGGCAGAGATACG
CCAGTCTGTCGCTTTAAACTTGCTTCGAGAAGAGTTGCAAATGTCGCAAACAGAGATGGCTGCGGCTATGGGGGTAAAGC
AGCCAACGATCGCTAAAATGGAACAGGCTGATAACGACCCTCGGCTTTCGACCCTAAAACGCTACATTGCGGCATTGGGG
GGAGAACTCAGTATAAATGTCACATTGCCGACTGGAAAAAAAGTCTCGTTTAATTTGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|