Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 1057852..1058606 Replicon chromosome
Accession NZ_CP090510
Organism Xylella fastidiosa subsp. multiplex strain LA-Y3C

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag LZ759_RS04535 Protein ID WP_021358673.1
Coordinates 1058127..1058606 (+) Length 160 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag LZ759_RS04530 Protein ID WP_004085396.1
Coordinates 1057852..1058124 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZ759_RS04515 (LZ759_04515) 1053600..1055633 - 2034 WP_234545896.1 glycoside hydrolase family 3 protein -
LZ759_RS04520 (LZ759_04520) 1055861..1056479 - 619 Protein_880 IS607 family transposase -
LZ759_RS04525 (LZ759_04525) 1056595..1057500 + 906 WP_040123139.1 AEC family transporter -
LZ759_RS04530 (LZ759_04530) 1057852..1058124 + 273 WP_004085396.1 DUF1778 domain-containing protein Antitoxin
LZ759_RS04535 (LZ759_04535) 1058127..1058606 + 480 WP_021358673.1 GNAT family N-acetyltransferase Toxin
LZ759_RS04540 (LZ759_04540) 1058942..1060006 - 1065 WP_080654483.1 toprim domain-containing protein -
LZ759_RS04545 (LZ759_04545) 1060052..1060126 - 75 Protein_885 hypothetical protein -
LZ759_RS04550 (LZ759_04550) 1060101..1061099 - 999 WP_004085391.1 MBL fold metallo-hydrolase -
LZ759_RS04555 (LZ759_04555) 1061230..1061916 - 687 WP_071869569.1 TIGR02453 family protein -
LZ759_RS04560 (LZ759_04560) 1061913..1063349 - 1437 WP_071869568.1 exodeoxyribonuclease I -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(33-146)

Antitoxin

Vibrio phage ICP1, Orf50

(3-85)


Sequences

Toxin        


Download         Length: 160 a.a.        Molecular weight: 17645.42 Da        Isoelectric Point: 9.9283

>T230956 WP_021358673.1 NZ_CP090510:1058127-1058606 [Xylella fastidiosa subsp. multiplex]
MQISTPHSLTAAHRLDEFNCGEPSLDDWLKRRALTNHLNGASRTFVVIDANQYVLGYYALAAGAVAHQEATRAIRRNMPD
PVPVMVLGRLAVDTRAQGIKLGAALLKDTVTRVQSIAENAGVRALVVHALNERAKQFYEYYGFRASPMHLMTLMLPIKF

Download         Length: 480 bp

>T230956 NZ_CP125733:135964-136269 [Escherichia coli]
ATGCAGTTTAAGGTTTACACCTATAAAAGAGAGAGCCGTTATCGTCTGTTTGTGGATGTCCAGAGTGACATTATTGACAC
GCCTGGGCGACGGATGGTGATCCCCCTGGCCAGTGCACGTCTGTTGTCAGATAAGGTCTCCCGTGAGCTTTACCCGGTGG
TGCATGTCGGGGATGAAAGCTGGCGCATGATGACCACCGATATGGCCAGTGTGCCGGTCTCCGTTATCGGGGAGGAAGTG
GCTGATCTCAGCCACCGAGAAAATGACATCAAAAATGCCATTAACCTGATGTTCTGGGGAATATAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10264.77 Da        Isoelectric Point: 5.0488

>AT230956 WP_004085396.1 NZ_CP090510:1057852-1058124 [Xylella fastidiosa subsp. multiplex]
MRDASINLRAMPEQRDLIDQAANLLGKNRSDFMLEAACERAKAIILDQVFFNLDEERFRQFTVLLNAPQDTNPGLNRLMA
IKAPWSISNT

Download         Length: 273 bp

>AT230956 NZ_CP125733:135744-135962 [Escherichia coli]
ATGAAGCAGCGCATTACAGTCACCGTCGACAGTGACAGCTATCAGTTGCTCAAGGCATATGATGTCAATATCTCCGGGCT
GATAAGCACCACCCTGCAGAATGAAGCCCGTCGTCTGCGTGCCGAACGCTGGCAGGCAGAAAATCAGGAAGGGATGGCTG
AGGTCGCCCGGTTTATTGAAATGAACGGCTCTTTTGCCGACGAGAACAGGGACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References