Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relE-dinJ/YafQ-RelB |
| Location | 2083974..2084505 | Replicon | chromosome |
| Accession | NZ_CP090508 | ||
| Organism | Xylella fastidiosa subsp. morus strain Riv11 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | A0A060HEY7 |
| Locus tag | LZ758_RS09765 | Protein ID | WP_038230161.1 |
| Coordinates | 2083974..2084255 (-) | Length | 94 a.a. |
Antitoxin (Protein)
| Gene name | dinJ | Uniprot ID | A0A060H9I0 |
| Locus tag | LZ758_RS09770 | Protein ID | WP_004086967.1 |
| Coordinates | 2084242..2084505 (-) | Length | 88 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LZ758_RS09725 (LZ758_09725) | 2079214..2079846 | + | 633 | WP_040123076.1 | phage portal protein | - |
| LZ758_RS09730 (LZ758_09730) | 2079843..2080847 | + | 1005 | WP_234509070.1 | HK97 family phage prohead protease | - |
| LZ758_RS09735 (LZ758_09735) | 2080916..2081716 | + | 801 | WP_234509132.1 | phage major capsid protein | - |
| LZ758_RS09740 (LZ758_09740) | 2081734..2081994 | + | 261 | WP_027700442.1 | hypothetical protein | - |
| LZ758_RS09745 (LZ758_09745) | 2081994..2082317 | + | 324 | WP_027700441.1 | hypothetical protein | - |
| LZ758_RS09750 (LZ758_09750) | 2082314..2082835 | + | 522 | WP_038230165.1 | hypothetical protein | - |
| LZ758_RS09755 (LZ758_09755) | 2082811..2083353 | + | 543 | WP_038230164.1 | hypothetical protein | - |
| LZ758_RS09760 (LZ758_09760) | 2083350..2083937 | + | 588 | WP_038230163.1 | phage baseplate assembly protein V | - |
| LZ758_RS09765 (LZ758_09765) | 2083974..2084255 | - | 282 | WP_038230161.1 | type II toxin-antitoxin system YafQ family toxin | Toxin |
| LZ758_RS09770 (LZ758_09770) | 2084242..2084505 | - | 264 | WP_004086967.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| LZ758_RS09775 (LZ758_09775) | 2084669..2084992 | + | 324 | WP_228304176.1 | GPW/gp25 family protein | - |
| LZ758_RS09780 (LZ758_09780) | 2084992..2085885 | + | 894 | WP_038230566.1 | baseplate J/gp47 family protein | - |
| LZ758_RS09785 (LZ758_09785) | 2085878..2086435 | + | 558 | WP_027700436.1 | phage tail protein I | - |
| LZ758_RS09790 (LZ758_09790) | 2086443..2087414 | + | 972 | WP_234056270.1 | phage tail protein | - |
| LZ758_RS09795 (LZ758_09795) | 2087332..2088021 | + | 690 | WP_230577660.1 | contractile injection system protein, VgrG/Pvc8 family | - |
| LZ758_RS09800 (LZ758_09800) | 2088437..2089456 | - | 1020 | WP_038230156.1 | tetraacyldisaccharide 4'-kinase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2072823..2105661 | 32838 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 94 a.a. Molecular weight: 10834.28 Da Isoelectric Point: 7.5505
>T230951 WP_038230161.1 NZ_CP090508:c2084255-2083974 [Xylella fastidiosa subsp. morus]
MRRISQTGQFKRDYKREAKGQHRATLDEELIHVVEALACDHPLEPRHHDHALTGGWKDHRDCHIKPDLVLIYRKPDNETL
QLVRIGSHSELGL
MRRISQTGQFKRDYKREAKGQHRATLDEELIHVVEALACDHPLEPRHHDHALTGGWKDHRDCHIKPDLVLIYRKPDNETL
QLVRIGSHSELGL
Download Length: 282 bp
>T230951 NZ_CP125731:c4220292-4219942 [Escherichia coli]
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GTGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTT
AATCAGGTGCGGATGATGGATCTACGCGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGATGAGGTGGTGGAAGAGGC
GTTATTACGCTTGCAGGCGGTGGTGGAATAA
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GTGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTT
AATCAGGTGCGGATGATGGATCTACGCGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGATGAGGTGGTGGAAGAGGC
GTTATTACGCTTGCAGGCGGTGGTGGAATAA
Antitoxin
Download Length: 88 a.a. Molecular weight: 9525.98 Da Isoelectric Point: 5.6033
>AT230951 WP_004086967.1 NZ_CP090508:c2084505-2084242 [Xylella fastidiosa subsp. morus]
MSANAVVRARVDTHIKEEASTVLATMGLSVSDAFRMMLTRIAREKALPFEPLVPNETTIAAMREARAGHLKSFDSIEALM
ADLHAED
MSANAVVRARVDTHIKEEASTVLATMGLSVSDAFRMMLTRIAREKALPFEPLVPNETTIAAMREARAGHLKSFDSIEALM
ADLHAED
Download Length: 264 bp
>AT230951 NZ_CP125731:c4220537-4220286 [Escherichia coli]
ATGCGTATTACCATAAAAAGATGGGGGAACAGTGCAGGTATGGTCATTCCCAATATCGTAATGAAAGAACTTAACTTACA
GCCGGGGCAGAGCGTGGAAGCGCAGGTGAGCAACAACCAACTGATTCTGACACCCATCTCCAGGCGCTACTCGCTTGATG
AACTGCTGGCACAGTGTGACATGAACGCCGCGGAACTTAGCGAGCAGGATGTCTGGGGTAAATCCACCCCTGCGGGTGAC
GAAATATGGTAA
ATGCGTATTACCATAAAAAGATGGGGGAACAGTGCAGGTATGGTCATTCCCAATATCGTAATGAAAGAACTTAACTTACA
GCCGGGGCAGAGCGTGGAAGCGCAGGTGAGCAACAACCAACTGATTCTGACACCCATCTCCAGGCGCTACTCGCTTGATG
AACTGCTGGCACAGTGTGACATGAACGCCGCGGAACTTAGCGAGCAGGATGTCTGGGGTAAATCCACCCCTGCGGGTGAC
GAAATATGGTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A060HEY7 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A060H9I0 |