Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | FicTA/Fic(toxin) |
| Location | 503814..504502 | Replicon | chromosome |
| Accession | NZ_CP090508 | ||
| Organism | Xylella fastidiosa subsp. morus strain Riv11 | ||
Toxin (Protein)
| Gene name | VbhT | Uniprot ID | - |
| Locus tag | LZ758_RS02305 | Protein ID | WP_230577608.1 |
| Coordinates | 503999..504502 (+) | Length | 168 a.a. |
Antitoxin (Protein)
| Gene name | VbhA | Uniprot ID | A0A060HF63 |
| Locus tag | LZ758_RS02300 | Protein ID | WP_004087046.1 |
| Coordinates | 503814..504002 (+) | Length | 63 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LZ758_RS02255 (LZ758_02255) | 499292..500572 | - | 1281 | WP_234056388.1 | DUF2800 domain-containing protein | - |
| LZ758_RS02260 (LZ758_02260) | 500569..501000 | - | 432 | WP_234056258.1 | hypothetical protein | - |
| LZ758_RS02265 (LZ758_02265) | 501057..501251 | - | 195 | WP_016024078.1 | hypothetical protein | - |
| LZ758_RS02270 (LZ758_02270) | 501283..501474 | - | 192 | WP_040123260.1 | hypothetical protein | - |
| LZ758_RS02275 (LZ758_02275) | 501498..501689 | - | 192 | WP_004087232.1 | hypothetical protein | - |
| LZ758_RS02280 (LZ758_02280) | 501686..502093 | - | 408 | WP_038230230.1 | hypothetical protein | - |
| LZ758_RS02285 (LZ758_02285) | 502090..502560 | - | 471 | WP_038230232.1 | DUF1566 domain-containing protein | - |
| LZ758_RS02290 (LZ758_02290) | 502557..502982 | - | 426 | WP_038230234.1 | hypothetical protein | - |
| LZ758_RS02295 (LZ758_02295) | 502979..503500 | - | 522 | WP_230577609.1 | hypothetical protein | - |
| LZ758_RS02300 (LZ758_02300) | 503814..504002 | + | 189 | WP_004087046.1 | antitoxin VbhA family protein | Antitoxin |
| LZ758_RS02305 (LZ758_02305) | 503999..504502 | + | 504 | WP_230577608.1 | Fic/DOC family protein | Toxin |
| LZ758_RS02310 (LZ758_02310) | 504661..505335 | - | 675 | WP_038230238.1 | helix-turn-helix transcriptional regulator | - |
| LZ758_RS12190 | 505538..505666 | + | 129 | WP_267964465.1 | hypothetical protein | - |
| LZ758_RS02315 (LZ758_02315) | 505656..506153 | + | 498 | WP_234056389.1 | hypothetical protein | - |
| LZ758_RS02320 (LZ758_02320) | 506214..506402 | + | 189 | WP_038230241.1 | hypothetical protein | - |
| LZ758_RS02325 (LZ758_02325) | 506432..506647 | + | 216 | WP_230577607.1 | hypothetical protein | - |
| LZ758_RS02330 (LZ758_02330) | 506665..506886 | + | 222 | WP_234056390.1 | hypothetical protein | - |
| LZ758_RS02335 (LZ758_02335) | 506931..507512 | + | 582 | WP_038230245.1 | Bro-N domain-containing protein | - |
| LZ758_RS02340 (LZ758_02340) | 507578..508687 | + | 1110 | WP_040123376.1 | Bro-N domain-containing protein | - |
| LZ758_RS02345 (LZ758_02345) | 508684..508944 | + | 261 | WP_230577606.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 433970..537918 | 103948 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 168 a.a. Molecular weight: 19106.56 Da Isoelectric Point: 6.7262
>T230941 WP_230577608.1 NZ_CP090508:503999-504502 [Xylella fastidiosa subsp. morus]
MKYAGDRGDPYLDSETGVLRNLLGIRDQGWLDKIESTLSFLRTSELRERPVKGKFDLAHLQEIHNRLFQDVYDWAGQIRQ
VEISKGNTMFAQQIAIQSAAQQIFGQLAKERFLCGLDAEEFSKRAGDYLGEINVLHPFREGNGRTQREFIAQLAQRAGYR
IDWGVVS
MKYAGDRGDPYLDSETGVLRNLLGIRDQGWLDKIESTLSFLRTSELRERPVKGKFDLAHLQEIHNRLFQDVYDWAGQIRQ
VEISKGNTMFAQQIAIQSAAQQIFGQLAKERFLCGLDAEEFSKRAGDYLGEINVLHPFREGNGRTQREFIAQLAQRAGYR
IDWGVVS
Download Length: 504 bp
>T230941 NZ_CP125731:1881305-1881559 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACACCATTTGAAGGTAAGGGGAAACCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACTGATGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACACCATTTGAAGGTAAGGGGAAACCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACTGATGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA
Antitoxin
Download Length: 63 a.a. Molecular weight: 6855.80 Da Isoelectric Point: 4.9859
>AT230941 WP_004087046.1 NZ_CP090508:503814-504002 [Xylella fastidiosa subsp. morus]
MLTDHEKAERRAVVQSALASQRIEGLEPDAQAVVDAECWARGEMTIAAAVDQYKARVRLQMA
MLTDHEKAERRAVVQSALASQRIEGLEPDAQAVVDAECWARGEMTIAAAVDQYKARVRLQMA
Download Length: 189 bp
>AT230941 NZ_CP125731:1881057-1881308 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|