Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relE-dinJ/YafQ-RelB |
| Location | 2115485..2116016 | Replicon | chromosome |
| Accession | NZ_CP090506 | ||
| Organism | Xylella fastidiosa subsp. morus strain Riv19 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | A0A060HEY7 |
| Locus tag | LZ757_RS09965 | Protein ID | WP_038230161.1 |
| Coordinates | 2115485..2115766 (-) | Length | 94 a.a. |
Antitoxin (Protein)
| Gene name | dinJ | Uniprot ID | A0A060H9I0 |
| Locus tag | LZ757_RS09970 | Protein ID | WP_004086967.1 |
| Coordinates | 2115753..2116016 (-) | Length | 88 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LZ757_RS09930 (LZ757_09930) | 2110724..2111356 | + | 633 | WP_040123076.1 | phage portal protein | - |
| LZ757_RS09935 (LZ757_09935) | 2111353..2113227 | + | 1875 | WP_038230171.1 | phage major capsid protein | - |
| LZ757_RS09940 (LZ757_09940) | 2113245..2113505 | + | 261 | WP_027700442.1 | hypothetical protein | - |
| LZ757_RS09945 (LZ757_09945) | 2113505..2113828 | + | 324 | WP_027700441.1 | hypothetical protein | - |
| LZ757_RS09950 (LZ757_09950) | 2113825..2114346 | + | 522 | WP_038230165.1 | hypothetical protein | - |
| LZ757_RS09955 (LZ757_09955) | 2114322..2114864 | + | 543 | WP_038230164.1 | hypothetical protein | - |
| LZ757_RS09960 (LZ757_09960) | 2114861..2115448 | + | 588 | WP_027700438.1 | phage baseplate assembly protein V | - |
| LZ757_RS09965 (LZ757_09965) | 2115485..2115766 | - | 282 | WP_038230161.1 | type II toxin-antitoxin system YafQ family toxin | Toxin |
| LZ757_RS09970 (LZ757_09970) | 2115753..2116016 | - | 264 | WP_004086967.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| LZ757_RS09975 (LZ757_09975) | 2116180..2116503 | + | 324 | WP_228304176.1 | GPW/gp25 family protein | - |
| LZ757_RS09980 (LZ757_09980) | 2116503..2117396 | + | 894 | WP_038230566.1 | baseplate J/gp47 family protein | - |
| LZ757_RS09985 (LZ757_09985) | 2117389..2117946 | + | 558 | WP_040123338.1 | phage tail protein I | - |
| LZ757_RS09990 (LZ757_09990) | 2117954..2118925 | + | 972 | WP_234056270.1 | phage tail protein | - |
| LZ757_RS09995 (LZ757_09995) | 2118855..2119532 | + | 678 | WP_234056269.1 | contractile injection system protein, VgrG/Pvc8 family | - |
| LZ757_RS10000 (LZ757_10000) | 2119948..2120967 | - | 1020 | WP_038230156.1 | tetraacyldisaccharide 4'-kinase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2104331..2127366 | 23035 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 94 a.a. Molecular weight: 10834.28 Da Isoelectric Point: 7.5505
>T230935 WP_038230161.1 NZ_CP090506:c2115766-2115485 [Xylella fastidiosa subsp. morus]
MRRISQTGQFKRDYKREAKGQHRATLDEELIHVVEALACDHPLEPRHHDHALTGGWKDHRDCHIKPDLVLIYRKPDNETL
QLVRIGSHSELGL
MRRISQTGQFKRDYKREAKGQHRATLDEELIHVVEALACDHPLEPRHHDHALTGGWKDHRDCHIKPDLVLIYRKPDNETL
QLVRIGSHSELGL
Download Length: 282 bp
>T230935 NZ_CP125731:656680-656994 [Escherichia coli]
ATGCACCTGATAACTCAAAAAGCATTGAAAGATGCTGCGGAAAAATACCCGCAACATAAAACGGAGTTGGTGGCTCTGGG
GAACACGATTGCTAAGGGATATTTCAAAAAACCTGAGTCATTAAAAGCAGTATTCCCATCTCTGGATAACTTCAAATATC
TGGATAAGCATTATGTTTTCAATGTTGGGGGCAATGAATTACGTGTTGTAGCAATGGTCTTTTTTGAATCGCAAAAGTGC
TACATACGTGAAGTTATGACGCATAAAGAATACGATTTCTTTACCGCTGTTCATCGTACTAAGGGGAAAAAATGA
ATGCACCTGATAACTCAAAAAGCATTGAAAGATGCTGCGGAAAAATACCCGCAACATAAAACGGAGTTGGTGGCTCTGGG
GAACACGATTGCTAAGGGATATTTCAAAAAACCTGAGTCATTAAAAGCAGTATTCCCATCTCTGGATAACTTCAAATATC
TGGATAAGCATTATGTTTTCAATGTTGGGGGCAATGAATTACGTGTTGTAGCAATGGTCTTTTTTGAATCGCAAAAGTGC
TACATACGTGAAGTTATGACGCATAAAGAATACGATTTCTTTACCGCTGTTCATCGTACTAAGGGGAAAAAATGA
Antitoxin
Download Length: 88 a.a. Molecular weight: 9525.98 Da Isoelectric Point: 5.6033
>AT230935 WP_004086967.1 NZ_CP090506:c2116016-2115753 [Xylella fastidiosa subsp. morus]
MSANAVVRARVDTHIKEEASTVLATMGLSVSDAFRMMLTRIAREKALPFEPLVPNETTIAAMREARAGHLKSFDSIEALM
ADLHAED
MSANAVVRARVDTHIKEEASTVLATMGLSVSDAFRMMLTRIAREKALPFEPLVPNETTIAAMREARAGHLKSFDSIEALM
ADLHAED
Download Length: 264 bp
>AT230935 NZ_CP125731:656991-657407 [Escherichia coli]
ATGATTGCGATTGCCGACATCTTGCAAGCAGGAGAAAAGCTAACTGCTGTGGCACCTTTTCTGGCGGGTATTCAGAACGA
GGAACAATACACCCAGGCGCTGGAACTGGTAGATCATCTGCTGCTCAACGATCCTGAAAACCCCTTGCTGGATCTGGTGT
GTGCCAAAATAACCGCGTGGGAAGAATCAGCGCCCGAATTTGCGGAATTTAATGCCATGGCTCAAGCCATGCCTGGCGGT
ATAGCCGTGATTCGTACCCTTATGGATCAATATGGTTTAACCCTTTCCGATCTGCCGGAAATTGGCAGTAAATCTATGGT
GTCACGCGTTTTGAGCGGGAAGAGGAAATTAACGCTGGAACACGCTAAAAAATTGGCAACGCGATTCGGCATTTCTCCCG
CCTTGTTTATTGATTAA
ATGATTGCGATTGCCGACATCTTGCAAGCAGGAGAAAAGCTAACTGCTGTGGCACCTTTTCTGGCGGGTATTCAGAACGA
GGAACAATACACCCAGGCGCTGGAACTGGTAGATCATCTGCTGCTCAACGATCCTGAAAACCCCTTGCTGGATCTGGTGT
GTGCCAAAATAACCGCGTGGGAAGAATCAGCGCCCGAATTTGCGGAATTTAATGCCATGGCTCAAGCCATGCCTGGCGGT
ATAGCCGTGATTCGTACCCTTATGGATCAATATGGTTTAACCCTTTCCGATCTGCCGGAAATTGGCAGTAAATCTATGGT
GTCACGCGTTTTGAGCGGGAAGAGGAAATTAACGCTGGAACACGCTAAAAAATTGGCAACGCGATTCGGCATTTCTCCCG
CCTTGTTTATTGATTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A060HEY7 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A060H9I0 |