230933

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsR-graA/MqsR-HigA
Location 1772532..1773197 Replicon chromosome
Accession NZ_CP090506
Organism Xylella fastidiosa subsp. morus strain Riv19

Toxin (Protein)


Gene name mqsR Uniprot ID A0A060HKF7
Locus tag LZ757_RS08435 Protein ID WP_038230541.1
Coordinates 1772895..1773197 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag LZ757_RS08430 Protein ID WP_004085172.1
Coordinates 1772532..1772807 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZ757_RS08405 (LZ757_08405) 1768661..1770253 - 1593 WP_040123119.1 tail fiber domain-containing protein -
LZ757_RS08410 (LZ757_08410) 1770261..1770818 - 558 WP_027700436.1 phage tail protein I -
LZ757_RS08415 (LZ757_08415) 1770811..1771704 - 894 WP_234056296.1 baseplate J/gp47 family protein -
LZ757_RS08420 (LZ757_08420) 1771704..1772027 - 324 WP_228304176.1 GPW/gp25 family protein -
LZ757_RS08425 (LZ757_08425) 1772240..1772521 + 282 WP_004085174.1 type II toxin-antitoxin system RelE/ParE family toxin -
LZ757_RS08430 (LZ757_08430) 1772532..1772807 + 276 WP_004085172.1 HigA family addiction module antitoxin Antitoxin
LZ757_RS08435 (LZ757_08435) 1772895..1773197 + 303 WP_038230541.1 type II toxin-antitoxin system MqsR family toxin Toxin
LZ757_RS08440 (LZ757_08440) 1773200..1773601 + 402 WP_004090697.1 type II toxin-antitoxin system MqsA family antitoxin -
LZ757_RS08445 (LZ757_08445) 1773670..1774257 - 588 WP_040123117.1 phage baseplate assembly protein V -
LZ757_RS08450 (LZ757_08450) 1774254..1774796 - 543 WP_038230164.1 hypothetical protein -
LZ757_RS08455 (LZ757_08455) 1774772..1775293 - 522 WP_038230165.1 hypothetical protein -
LZ757_RS08460 (LZ757_08460) 1775290..1775613 - 324 WP_027700441.1 hypothetical protein -
LZ757_RS08465 (LZ757_08465) 1775613..1775873 - 261 WP_027700442.1 hypothetical protein -
LZ757_RS08470 (LZ757_08470) 1775891..1777765 - 1875 WP_038230171.1 phage major capsid protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1752103..1802800 50697


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-99)

Antitoxin

Cro/C1-type helix-turn-helix domain

(15-64)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 10972.77 Da        Isoelectric Point: 8.0251

>T230933 WP_038230541.1 NZ_CP090506:1772895-1773197 [Xylella fastidiosa subsp. morus]
MEKGTPHYKLPVVKALVKAGKVRATATAYQGARELGIKDLTGMCAVVLALTSADFYKSMTTYTDHTLFQDVYHAKTASGD
EVYLKLTVIDDVLIVSFKEL

Download         Length: 303 bp

>T230933 NZ_CP125731:196066-196173 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10072.68 Da        Isoelectric Point: 10.2184

>AT230933 WP_004085172.1 NZ_CP090506:1772532-1772807 [Xylella fastidiosa subsp. morus]
MKRMHNPAHPGEVLREYLGELTVTNAAAKLGVSRVALSRILNGTNGISADMALRLEDALGTSAEMWAAMQFKYDLWVASQ
QPRPKITRLHV

Download         Length: 276 bp

>AT230933 NZ_CP125731:c196018-195952 [Escherichia coli]
GGTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A060HKF7

Antitoxin

Source ID Structure

References