Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/upstrm_HI1419-dnstrm_HI1420 |
Location | 529877..530488 | Replicon | chromosome |
Accession | NZ_CP090506 | ||
Organism | Xylella fastidiosa subsp. morus strain Riv19 |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A060HHU8 |
Locus tag | LZ757_RS02505 | Protein ID | WP_024749166.1 |
Coordinates | 530189..530488 (-) | Length | 100 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | Q879U0 |
Locus tag | LZ757_RS02500 | Protein ID | WP_004085003.1 |
Coordinates | 529877..530185 (-) | Length | 103 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LZ757_RS02475 (LZ757_02475) | 525014..525403 | + | 390 | WP_234492563.1 | hypothetical protein | - |
LZ757_RS02480 (LZ757_02480) | 525404..526900 | + | 1497 | WP_038230289.1 | DUF3383 domain-containing protein | - |
LZ757_RS02485 (LZ757_02485) | 526910..527347 | + | 438 | WP_038230291.1 | DUF3277 family protein | - |
LZ757_RS02490 (LZ757_02490) | 527344..527766 | + | 423 | WP_011097875.1 | putative phage tail assembly chaperone | - |
LZ757_RS02495 (LZ757_02495) | 527914..529803 | + | 1890 | WP_038230294.1 | hypothetical protein | - |
LZ757_RS02500 (LZ757_02500) | 529877..530185 | - | 309 | WP_004085003.1 | putative addiction module antidote protein | Antitoxin |
LZ757_RS02505 (LZ757_02505) | 530189..530488 | - | 300 | WP_024749166.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
LZ757_RS02510 (LZ757_02510) | 530576..530881 | + | 306 | WP_230577600.1 | hypothetical protein | - |
LZ757_RS02515 (LZ757_02515) | 530897..531346 | + | 450 | WP_230577599.1 | hypothetical protein | - |
LZ757_RS02520 (LZ757_02520) | 531346..531663 | + | 318 | WP_012382585.1 | hypothetical protein | - |
LZ757_RS02525 (LZ757_02525) | 531660..532490 | + | 831 | WP_234056377.1 | hypothetical protein | - |
LZ757_RS02530 (LZ757_02530) | 532487..533128 | + | 642 | WP_040123250.1 | Gp138 family membrane-puncturing spike protein | - |
LZ757_RS02535 (LZ757_02535) | 533125..533478 | + | 354 | WP_040123277.1 | hypothetical protein | - |
LZ757_RS02540 (LZ757_02540) | 533534..533827 | - | 294 | WP_004085592.1 | putative addiction module antidote protein | - |
LZ757_RS02545 (LZ757_02545) | 533830..534126 | - | 297 | WP_004085590.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
LZ757_RS02550 (LZ757_02550) | 534229..534987 | + | 759 | WP_234492567.1 | baseplate J/gp47 family protein | - |
LZ757_RS02555 (LZ757_02555) | 535017..535373 | + | 357 | WP_228762937.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 437682..539227 | 101545 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 100 a.a. Molecular weight: 11364.14 Da Isoelectric Point: 10.3861
>T230926 WP_024749166.1 NZ_CP090506:c530488-530189 [Xylella fastidiosa subsp. morus]
MTYTVKRLEGFSDWLKGLKDGLARQRLIKRLRKVQLGNFGDVQPVGEGVFEMREHFGPGWRMYYVQRGSFLIVMLGGGDK
STQQSDIRRAIELAKSLED
MTYTVKRLEGFSDWLKGLKDGLARQRLIKRLRKVQLGNFGDVQPVGEGVFEMREHFGPGWRMYYVQRGSFLIVMLGGGDK
STQQSDIRRAIELAKSLED
Download Length: 300 bp
>T230926 NZ_CP125672:542277-542618 [Leptospira kirschneri]
ATGATTCGTGGTGAGATCTGGTGGGTAGACTTAGGAATTCCATTCGGAAGTGAACCTGGGTTTAAGCGTCCAGTTTTGAT
TATTCAAGATGACTCTTTTAATCAAAGTAATATCAGTACTGTAGTATCGATTGCGATTACATCAAATTTAAATTTGTCTG
AAGCTCCTGGCAACGTTTTGATCGGTAAGAAAGAATCCAGCTTATCAAAAGATTCAGTTGTGAATGTCTCTCAAATTGTG
ACTTTAGATAAGGAAAGGTTTATTGAACGAGTGGGAAAGCTTAAATCAAGTAAGATCAATGAAGTTGAAGTAGGTCTCAA
ATTAGTTACAGGTTTAGATTAA
ATGATTCGTGGTGAGATCTGGTGGGTAGACTTAGGAATTCCATTCGGAAGTGAACCTGGGTTTAAGCGTCCAGTTTTGAT
TATTCAAGATGACTCTTTTAATCAAAGTAATATCAGTACTGTAGTATCGATTGCGATTACATCAAATTTAAATTTGTCTG
AAGCTCCTGGCAACGTTTTGATCGGTAAGAAAGAATCCAGCTTATCAAAAGATTCAGTTGTGAATGTCTCTCAAATTGTG
ACTTTAGATAAGGAAAGGTTTATTGAACGAGTGGGAAAGCTTAAATCAAGTAAGATCAATGAAGTTGAAGTAGGTCTCAA
ATTAGTTACAGGTTTAGATTAA
Antitoxin
Download Length: 103 a.a. Molecular weight: 11060.61 Da Isoelectric Point: 4.6535
>AT230926 WP_004085003.1 NZ_CP090506:c530185-529877 [Xylella fastidiosa subsp. morus]
VTITKKINVSELPEFDAAEYLNSEEEVAAYLTAVLEENDPALLAAALGDIARSRGMSQIAKDSGITREALYKALRPGSEP
RFDTISRVCTALGIRLVAQPMH
VTITKKINVSELPEFDAAEYLNSEEEVAAYLTAVLEENDPALLAAALGDIARSRGMSQIAKDSGITREALYKALRPGSEP
RFDTISRVCTALGIRLVAQPMH
Download Length: 309 bp
>AT230926 NZ_CP125672:542042-542290 [Leptospira kirschneri]
ATGAAAACTGCAATTTCGATTCCAGATGAATTATTCAAGACTGCTGAGAAAACGGCAAAAAAACTTGGAATACCTCGAAG
CCAACTCTTTGCAAAAGCATTAGAAGAATTTATTCAATCCCATAGTAAAGAATCTGTAACAGAGAAATTAAATAAAATTT
ATAACAGAAAATCCAAAGAACTTAAAAGTAATATCACAGATTTATCTGTAGAGTTATTGCGCAAGAGTTTAAAAAATGAT
TCGTGGTGA
ATGAAAACTGCAATTTCGATTCCAGATGAATTATTCAAGACTGCTGAGAAAACGGCAAAAAAACTTGGAATACCTCGAAG
CCAACTCTTTGCAAAAGCATTAGAAGAATTTATTCAATCCCATAGTAAAGAATCTGTAACAGAGAAATTAAATAAAATTT
ATAACAGAAAATCCAAAGAACTTAAAAGTAATATCACAGATTTATCTGTAGAGTTATTGCGCAAGAGTTTAAAAAATGAT
TCGTGGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A060HHU8 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A060HCD4 |