Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | FicTA/Fic(toxin) |
| Location | 502956..503644 | Replicon | chromosome |
| Accession | NZ_CP090506 | ||
| Organism | Xylella fastidiosa subsp. morus strain Riv19 | ||
Toxin (Protein)
| Gene name | VbhT | Uniprot ID | - |
| Locus tag | LZ757_RS02300 | Protein ID | WP_230577608.1 |
| Coordinates | 503141..503644 (+) | Length | 168 a.a. |
Antitoxin (Protein)
| Gene name | VbhA | Uniprot ID | A0A060HF63 |
| Locus tag | LZ757_RS02295 | Protein ID | WP_004087046.1 |
| Coordinates | 502956..503144 (+) | Length | 63 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LZ757_RS02250 (LZ757_02250) | 498435..499715 | - | 1281 | WP_234492538.1 | DUF2800 domain-containing protein | - |
| LZ757_RS02255 (LZ757_02255) | 499712..500209 | - | 498 | WP_234492537.1 | hypothetical protein | - |
| LZ757_RS02260 (LZ757_02260) | 500199..500393 | - | 195 | WP_016024078.1 | hypothetical protein | - |
| LZ757_RS02265 (LZ757_02265) | 500425..500616 | - | 192 | WP_040123260.1 | hypothetical protein | - |
| LZ757_RS02270 (LZ757_02270) | 500640..500831 | - | 192 | WP_004087232.1 | hypothetical protein | - |
| LZ757_RS02275 (LZ757_02275) | 500828..501235 | - | 408 | WP_038230230.1 | hypothetical protein | - |
| LZ757_RS02280 (LZ757_02280) | 501232..501702 | - | 471 | WP_038230232.1 | DUF1566 domain-containing protein | - |
| LZ757_RS02285 (LZ757_02285) | 501699..502124 | - | 426 | WP_038230234.1 | hypothetical protein | - |
| LZ757_RS02290 (LZ757_02290) | 502121..502642 | - | 522 | WP_230577609.1 | hypothetical protein | - |
| LZ757_RS02295 (LZ757_02295) | 502956..503144 | + | 189 | WP_004087046.1 | antitoxin VbhA family protein | Antitoxin |
| LZ757_RS02300 (LZ757_02300) | 503141..503644 | + | 504 | WP_230577608.1 | Fic/DOC family protein | Toxin |
| LZ757_RS02305 (LZ757_02305) | 503803..504477 | - | 675 | WP_038230238.1 | helix-turn-helix transcriptional regulator | - |
| LZ757_RS12180 | 504683..504808 | + | 126 | WP_267959509.1 | hypothetical protein | - |
| LZ757_RS02310 (LZ757_02310) | 504798..505295 | + | 498 | WP_234056389.1 | hypothetical protein | - |
| LZ757_RS02315 (LZ757_02315) | 505356..505544 | + | 189 | WP_038230241.1 | hypothetical protein | - |
| LZ757_RS02320 (LZ757_02320) | 505574..505789 | + | 216 | WP_230577607.1 | hypothetical protein | - |
| LZ757_RS02325 (LZ757_02325) | 505807..506028 | + | 222 | WP_234056390.1 | hypothetical protein | - |
| LZ757_RS02330 (LZ757_02330) | 506073..506654 | + | 582 | WP_038230245.1 | Bro-N domain-containing protein | - |
| LZ757_RS02335 (LZ757_02335) | 506720..507829 | + | 1110 | WP_040123376.1 | Bro-N domain-containing protein | - |
| LZ757_RS02340 (LZ757_02340) | 507826..508086 | + | 261 | WP_230577606.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 437682..539227 | 101545 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 168 a.a. Molecular weight: 19106.56 Da Isoelectric Point: 6.7262
>T230925 WP_230577608.1 NZ_CP090506:503141-503644 [Xylella fastidiosa subsp. morus]
MKYAGDRGDPYLDSETGVLRNLLGIRDQGWLDKIESTLSFLRTSELRERPVKGKFDLAHLQEIHNRLFQDVYDWAGQIRQ
VEISKGNTMFAQQIAIQSAAQQIFGQLAKERFLCGLDAEEFSKRAGDYLGEINVLHPFREGNGRTQREFIAQLAQRAGYR
IDWGVVS
MKYAGDRGDPYLDSETGVLRNLLGIRDQGWLDKIESTLSFLRTSELRERPVKGKFDLAHLQEIHNRLFQDVYDWAGQIRQ
VEISKGNTMFAQQIAIQSAAQQIFGQLAKERFLCGLDAEEFSKRAGDYLGEINVLHPFREGNGRTQREFIAQLAQRAGYR
IDWGVVS
Download Length: 504 bp
>T230925 NZ_CP125669:c3205788-3205381 [Acinetobacter sp. KCTC 92772]
ATGCTTAAATACATGCTGGATACCAACATCTGCATCTATGCGATTAAGAAAAAGCCGATTGAAGTCATCCAACAGTTTTC
CAAGTATCAGGATTATCTTTGTATCAGCTCGATCACCTTAATGGAGTTGTATTACGGTGCAGAAAAATCATCCAATCCCC
AAACTAATCTGACTGAAATTGAAAAATTTGTGGCAAATCTGATCGTCCTTGATTATGACAATTATGCCGCAGCACATACC
GCACAAATTCGGGCTGAACTATCAAAAACAGGCAAAACTATTGGCAGTTATGATGCCATGATTGCAGGGCATGCCCGTAG
TCAGGGATTCATTTGTGTCACTAATAACATACGTGAGTTTGAACGTGTGGCTGGATTACGTCTAGAGAATTGGTGGGTGC
AGTCTTAA
ATGCTTAAATACATGCTGGATACCAACATCTGCATCTATGCGATTAAGAAAAAGCCGATTGAAGTCATCCAACAGTTTTC
CAAGTATCAGGATTATCTTTGTATCAGCTCGATCACCTTAATGGAGTTGTATTACGGTGCAGAAAAATCATCCAATCCCC
AAACTAATCTGACTGAAATTGAAAAATTTGTGGCAAATCTGATCGTCCTTGATTATGACAATTATGCCGCAGCACATACC
GCACAAATTCGGGCTGAACTATCAAAAACAGGCAAAACTATTGGCAGTTATGATGCCATGATTGCAGGGCATGCCCGTAG
TCAGGGATTCATTTGTGTCACTAATAACATACGTGAGTTTGAACGTGTGGCTGGATTACGTCTAGAGAATTGGTGGGTGC
AGTCTTAA
Antitoxin
Download Length: 63 a.a. Molecular weight: 6855.80 Da Isoelectric Point: 4.9859
>AT230925 WP_004087046.1 NZ_CP090506:502956-503144 [Xylella fastidiosa subsp. morus]
MLTDHEKAERRAVVQSALASQRIEGLEPDAQAVVDAECWARGEMTIAAAVDQYKARVRLQMA
MLTDHEKAERRAVVQSALASQRIEGLEPDAQAVVDAECWARGEMTIAAAVDQYKARVRLQMA
Download Length: 189 bp
>AT230925 NZ_CP125669:c3206024-3205791 [Acinetobacter sp. KCTC 92772]
ATGGAAAAAGCAACGATCTTTAAAAATAATCGCAACCAAGCGGTACGTTTGCCCAAAGCAGTTGCTTTTCCTGAACATAT
CAAACAGGTGGAAGTGATTAGTATTGGGGATACACGGATTTTAACCCCTATTGGAAAACGATGGGAATTATGGATGAATA
CGCCATCACAACTGACCGAAGATTGTTTTCAGGAACGTGACCAACCGATTGCGCAAGAACGAGAAAGTTTCTAA
ATGGAAAAAGCAACGATCTTTAAAAATAATCGCAACCAAGCGGTACGTTTGCCCAAAGCAGTTGCTTTTCCTGAACATAT
CAAACAGGTGGAAGTGATTAGTATTGGGGATACACGGATTTTAACCCCTATTGGAAAACGATGGGAATTATGGATGAATA
CGCCATCACAACTGACCGAAGATTGTTTTCAGGAACGTGACCAACCGATTGCGCAAGAACGAGAAAGTTTCTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|