Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PumA-relB/COG3657-dnstrm_HI1420 |
| Location | 482537..483142 | Replicon | chromosome |
| Accession | NZ_CP090506 | ||
| Organism | Xylella fastidiosa subsp. morus strain Riv19 | ||
Toxin (Protein)
| Gene name | PumA | Uniprot ID | B2I5N3 |
| Locus tag | LZ757_RS02160 | Protein ID | WP_004089252.1 |
| Coordinates | 482846..483142 (-) | Length | 99 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | LZ757_RS02155 | Protein ID | WP_038211623.1 |
| Coordinates | 482537..482842 (-) | Length | 102 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LZ757_RS02115 (LZ757_02115) | 478925..479233 | - | 309 | WP_004085003.1 | putative addiction module antidote protein | - |
| LZ757_RS02120 (LZ757_02120) | 479237..479536 | - | 300 | WP_024749166.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| LZ757_RS02125 (LZ757_02125) | 479624..479929 | + | 306 | WP_230577600.1 | hypothetical protein | - |
| LZ757_RS02130 (LZ757_02130) | 479945..480394 | + | 450 | WP_230577599.1 | hypothetical protein | - |
| LZ757_RS02135 (LZ757_02135) | 480394..480711 | + | 318 | WP_012382585.1 | hypothetical protein | - |
| LZ757_RS02140 (LZ757_02140) | 480708..481538 | + | 831 | WP_234056377.1 | hypothetical protein | - |
| LZ757_RS02145 (LZ757_02145) | 481535..482176 | + | 642 | WP_040123250.1 | Gp138 family membrane-puncturing spike protein | - |
| LZ757_RS02150 (LZ757_02150) | 482173..482526 | + | 354 | WP_234056392.1 | hypothetical protein | - |
| LZ757_RS02155 (LZ757_02155) | 482537..482842 | - | 306 | WP_038211623.1 | putative addiction module antidote protein | Antitoxin |
| LZ757_RS02160 (LZ757_02160) | 482846..483142 | - | 297 | WP_004089252.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LZ757_RS02165 (LZ757_02165) | 483241..483999 | + | 759 | WP_234492564.1 | baseplate J/gp47 family protein | - |
| LZ757_RS02170 (LZ757_02170) | 484029..484385 | + | 357 | WP_228762937.1 | hypothetical protein | - |
| LZ757_RS02175 (LZ757_02175) | 484382..484942 | + | 561 | WP_004084996.1 | DUF2612 domain-containing protein | - |
| LZ757_RS02180 (LZ757_02180) | 484946..486109 | + | 1164 | WP_234056379.1 | tail fiber protein | - |
| LZ757_RS02185 (LZ757_02185) | 486356..487009 | + | 654 | WP_038211241.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 437682..539227 | 101545 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 99 a.a. Molecular weight: 10790.57 Da Isoelectric Point: 10.0509
>T230924 WP_004089252.1 NZ_CP090506:c483142-482846 [Xylella fastidiosa subsp. morus]
MVELIKTSTFDAWINSLRDRKAAARIQARLDRLALGNPGDVKPVGAGISEMRIDHGPGYRIYFMKHGAVLILLLCGGDKS
SQVRDIEQAKALAALWKD
MVELIKTSTFDAWINSLRDRKAAARIQARLDRLALGNPGDVKPVGAGISEMRIDHGPGYRIYFMKHGAVLILLLCGGDKS
SQVRDIEQAKALAALWKD
Download Length: 297 bp
>T230924 NZ_CP125669:c3060358-3060083 [Acinetobacter sp. KCTC 92772]
ATGATTGATGATGATTCCTATGCCAAGCTACAACAGGCATTAAACGAAGATCCCGAATTGGGTGATCTTATACGTGCAAG
TGGTGGGATACGCAAGGTCAGATGGAATCTAGAACATACGGGGAAAAGTGGTGGTATCCGTGTCATTTATTACTACTTTG
ATAACGAGGGGCAAATATTTATGCTGCTTGCTTATCCAAAGTCAGTTAAGGATAATTTAACTGACCGTGAACTCACTGTG
TTACGCAAACTTGTGGAGGAGTTAAAAAATGTCTGA
ATGATTGATGATGATTCCTATGCCAAGCTACAACAGGCATTAAACGAAGATCCCGAATTGGGTGATCTTATACGTGCAAG
TGGTGGGATACGCAAGGTCAGATGGAATCTAGAACATACGGGGAAAAGTGGTGGTATCCGTGTCATTTATTACTACTTTG
ATAACGAGGGGCAAATATTTATGCTGCTTGCTTATCCAAAGTCAGTTAAGGATAATTTAACTGACCGTGAACTCACTGTG
TTACGCAAACTTGTGGAGGAGTTAAAAAATGTCTGA
Antitoxin
Download Length: 102 a.a. Molecular weight: 10982.42 Da Isoelectric Point: 5.0941
>AT230924 WP_038211623.1 NZ_CP090506:c482842-482537 [Xylella fastidiosa subsp. morus]
MNNETFSRYDTADYLKTEEDIAAYMEAVMEEGGRDNPAFIARALGAVARARNLSQLARDVGMSRQGLDKALSIDGNPSFS
TILKVAKALGLRMSFTPSSMS
MNNETFSRYDTADYLKTEEDIAAYMEAVMEEGGRDNPAFIARALGAVARARNLSQLARDVGMSRQGLDKALSIDGNPSFS
TILKVAKALGLRMSFTPSSMS
Download Length: 306 bp
>AT230924 NZ_CP125669:c3060090-3059812 [Acinetobacter sp. KCTC 92772]
ATGTCTGAGTTTTTTGATGAATTAACAGAAGCCTTGGAACAAGCTATCGCAGTACGGAAAGGTGAAATGCCTGCTAGTCG
TGAATTTAGCCTTGAACGACCAAATATCAAGGCAATTCGTGAAAAAACAGGACTTTCTCAGGTTCAATTTGCGAAACGTC
TACACATTAGCCCACGCACCCTGCAAAACTGGGAGCAAGGGCATCGTTACCCAACTGGACCAGCCATTGCCCTGATTCAT
ATTATTGATAAAAACCCCAATATTTTGACGATGGCATAA
ATGTCTGAGTTTTTTGATGAATTAACAGAAGCCTTGGAACAAGCTATCGCAGTACGGAAAGGTGAAATGCCTGCTAGTCG
TGAATTTAGCCTTGAACGACCAAATATCAAGGCAATTCGTGAAAAAACAGGACTTTCTCAGGTTCAATTTGCGAAACGTC
TACACATTAGCCCACGCACCCTGCAAAACTGGGAGCAAGGGCATCGTTACCCAACTGGACCAGCCATTGCCCTGATTCAT
ATTATTGATAAAAACCCCAATATTTTGACGATGGCATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|