Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/upstrm_HI1419-dnstrm_HI1420 |
Location | 478925..479536 | Replicon | chromosome |
Accession | NZ_CP090506 | ||
Organism | Xylella fastidiosa subsp. morus strain Riv19 |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A060HHU8 |
Locus tag | LZ757_RS02120 | Protein ID | WP_024749166.1 |
Coordinates | 479237..479536 (-) | Length | 100 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | Q879U0 |
Locus tag | LZ757_RS02115 | Protein ID | WP_004085003.1 |
Coordinates | 478925..479233 (-) | Length | 103 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LZ757_RS02090 (LZ757_02090) | 474062..474451 | + | 390 | WP_234492563.1 | hypothetical protein | - |
LZ757_RS02095 (LZ757_02095) | 474452..475948 | + | 1497 | WP_038230289.1 | DUF3383 domain-containing protein | - |
LZ757_RS02100 (LZ757_02100) | 475958..476395 | + | 438 | WP_038230291.1 | DUF3277 family protein | - |
LZ757_RS02105 (LZ757_02105) | 476392..476814 | + | 423 | WP_011097875.1 | putative phage tail assembly chaperone | - |
LZ757_RS02110 (LZ757_02110) | 476962..478851 | + | 1890 | WP_038230294.1 | hypothetical protein | - |
LZ757_RS02115 (LZ757_02115) | 478925..479233 | - | 309 | WP_004085003.1 | putative addiction module antidote protein | Antitoxin |
LZ757_RS02120 (LZ757_02120) | 479237..479536 | - | 300 | WP_024749166.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
LZ757_RS02125 (LZ757_02125) | 479624..479929 | + | 306 | WP_230577600.1 | hypothetical protein | - |
LZ757_RS02130 (LZ757_02130) | 479945..480394 | + | 450 | WP_230577599.1 | hypothetical protein | - |
LZ757_RS02135 (LZ757_02135) | 480394..480711 | + | 318 | WP_012382585.1 | hypothetical protein | - |
LZ757_RS02140 (LZ757_02140) | 480708..481538 | + | 831 | WP_234056377.1 | hypothetical protein | - |
LZ757_RS02145 (LZ757_02145) | 481535..482176 | + | 642 | WP_040123250.1 | Gp138 family membrane-puncturing spike protein | - |
LZ757_RS02150 (LZ757_02150) | 482173..482526 | + | 354 | WP_234056392.1 | hypothetical protein | - |
LZ757_RS02155 (LZ757_02155) | 482537..482842 | - | 306 | WP_038211623.1 | putative addiction module antidote protein | - |
LZ757_RS02160 (LZ757_02160) | 482846..483142 | - | 297 | WP_004089252.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
LZ757_RS02165 (LZ757_02165) | 483241..483999 | + | 759 | WP_234492564.1 | baseplate J/gp47 family protein | - |
LZ757_RS02170 (LZ757_02170) | 484029..484385 | + | 357 | WP_228762937.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 437682..539227 | 101545 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 100 a.a. Molecular weight: 11364.14 Da Isoelectric Point: 10.3861
>T230923 WP_024749166.1 NZ_CP090506:c479536-479237 [Xylella fastidiosa subsp. morus]
MTYTVKRLEGFSDWLKGLKDGLARQRLIKRLRKVQLGNFGDVQPVGEGVFEMREHFGPGWRMYYVQRGSFLIVMLGGGDK
STQQSDIRRAIELAKSLED
MTYTVKRLEGFSDWLKGLKDGLARQRLIKRLRKVQLGNFGDVQPVGEGVFEMREHFGPGWRMYYVQRGSFLIVMLGGGDK
STQQSDIRRAIELAKSLED
Download Length: 300 bp
>T230923 NZ_CP125669:2763152-2763547 [Acinetobacter sp. KCTC 92772]
ATGTCCACGGCTAATCGTGTTTTTGAGTTGCAAGCCAGTCGCTTTATGATTGTTTTGCAACTGTTAATTTTTATTTTCCT
GATGATTTTACTCTATCAGCTATTAGCTTTGGGGATTTGGCTGCTGTGTCTGGGGATCATGGTCATTGCCTGGTTCAGGT
TTTTGCAGCAACCTCAAGTCAAGCGTTTTGAACATCTGGAAGATCAAGACTGGTCATTTGAGTTTGCCGTTTCAGATCTG
CCGATACAGCGTCGGCAAATTGTGAAAATGATCGACCACCACTGCTATGTTGTCCTCTATTTTTCTGCTTCTCATGACAA
AACCTGCATCATTTGGTGGGATCAATTGCCCGTTACACAGTGGAAAAACCTAAAAACACTGGTAAAACTATGCTAA
ATGTCCACGGCTAATCGTGTTTTTGAGTTGCAAGCCAGTCGCTTTATGATTGTTTTGCAACTGTTAATTTTTATTTTCCT
GATGATTTTACTCTATCAGCTATTAGCTTTGGGGATTTGGCTGCTGTGTCTGGGGATCATGGTCATTGCCTGGTTCAGGT
TTTTGCAGCAACCTCAAGTCAAGCGTTTTGAACATCTGGAAGATCAAGACTGGTCATTTGAGTTTGCCGTTTCAGATCTG
CCGATACAGCGTCGGCAAATTGTGAAAATGATCGACCACCACTGCTATGTTGTCCTCTATTTTTCTGCTTCTCATGACAA
AACCTGCATCATTTGGTGGGATCAATTGCCCGTTACACAGTGGAAAAACCTAAAAACACTGGTAAAACTATGCTAA
Antitoxin
Download Length: 103 a.a. Molecular weight: 11060.61 Da Isoelectric Point: 4.6535
>AT230923 WP_004085003.1 NZ_CP090506:c479233-478925 [Xylella fastidiosa subsp. morus]
VTITKKINVSELPEFDAAEYLNSEEEVAAYLTAVLEENDPALLAAALGDIARSRGMSQIAKDSGITREALYKALRPGSEP
RFDTISRVCTALGIRLVAQPMH
VTITKKINVSELPEFDAAEYLNSEEEVAAYLTAVLEENDPALLAAALGDIARSRGMSQIAKDSGITREALYKALRPGSEP
RFDTISRVCTALGIRLVAQPMH
Download Length: 309 bp
>AT230923 NZ_CP125669:2762908-2763165 [Acinetobacter sp. KCTC 92772]
ATGTCCGATGAAATGACACTTGAAGAACGTAAGGTGATTTATCGTTCACGTCGTGGTTTAAAAGAAATTGATGTGTATTT
TGATCCCTACGTCAAAAACTATTATCTCAGTGCAGACCCAGCAGAAAAGGCCTTGTTTGCCGAACTGGTTGATCAGGAAG
ACCCTGACTTGCTGGACTGGTTTATGGAAGTGGGTGAAGCGCCAAGAGCTGAAATCAAGGAATTTATCCTAAAATTAAAA
CAGTATGTCCACGGCTAA
ATGTCCGATGAAATGACACTTGAAGAACGTAAGGTGATTTATCGTTCACGTCGTGGTTTAAAAGAAATTGATGTGTATTT
TGATCCCTACGTCAAAAACTATTATCTCAGTGCAGACCCAGCAGAAAAGGCCTTGTTTGCCGAACTGGTTGATCAGGAAG
ACCCTGACTTGCTGGACTGGTTTATGGAAGTGGGTGAAGCGCCAAGAGCTGAAATCAAGGAATTTATCCTAAAATTAAAA
CAGTATGTCCACGGCTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A060HHU8 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A060HCD4 |