Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3146064..3146710 Replicon chromosome
Accession NZ_CP090484
Organism Burkholderia sp. S-53

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LXM88_RS36175 Protein ID WP_262544255.1
Coordinates 3146303..3146710 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LXM88_RS36170 Protein ID WP_129517050.1
Coordinates 3146064..3146306 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LXM88_RS36155 (LXM88_36095) 3142053..3143459 + 1407 WP_262544252.1 aspartate ammonia-lyase -
LXM88_RS36160 (LXM88_36100) 3143562..3145067 + 1506 WP_262544253.1 amino acid permease -
LXM88_RS36165 (LXM88_36105) 3145120..3145803 - 684 WP_262544254.1 phospholipase -
LXM88_RS36170 (LXM88_36110) 3146064..3146306 + 243 WP_129517050.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
LXM88_RS36175 (LXM88_36115) 3146303..3146710 + 408 WP_262544255.1 type II toxin-antitoxin system VapC family toxin Toxin
LXM88_RS36180 (LXM88_36120) 3146810..3148297 - 1488 WP_262544256.1 aldehyde dehydrogenase -
LXM88_RS36185 (LXM88_36125) 3148316..3148894 - 579 WP_262544257.1 thioesterase family protein -
LXM88_RS36190 (LXM88_36130) 3149157..3150287 + 1131 WP_262544258.1 porin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-122)

Antitoxin

SpoVT-AbrB domain

(7-51)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 14881.92 Da        Isoelectric Point: 5.6119

>T230898 WP_262544255.1 NZ_CP090484:3146303-3146710 [Burkholderia sp. S-53]
MKFLLDTNAVIAILKGEPAMLTRLRAHQPADFGIPAIVAHELYYGAYKSQRVAANLARVEGLQFEVVSFDAEDAQHAGEI
RAQLTAAGTPIGPYDALIAGQARARRLVLVTHNTREFERVAELQVEDWLADAREN

Download         Length: 408 bp

>T230898 NZ_CP125651:c654176-653751 [Rhizobium sp. BT04]
ATGATTATCCTCGATACGAACGTCGTTTCCGAGGCGATGAAACCCGCGCCCGACGAAGCCGTGAAATTCTGGCTCGATGA
GCAGGCAGCCGAAACCCTCTTCCTTTCCAGCGTCACCATCGCCGAACTGATGTTTGGTATCGGCGCGCTCCCGCCCGGCA
AACGCAAAGAAAGGCTCTCAGAGGCGTTGGACGGTCTGATGGAGCTCTTCGAAAACCGTATTCTGGCCTTCGACATCACC
GCGGCACGGCATTATGCCGACCTCGCCGTCAAGGCTCGCGCCGCTGGCAGAGGTTTCCCCACGCCGGATGGTTATATTGC
CGCCATTGCGGCGTCAAAAGGGTTTGTCGTCGCCACGCGCGATACAAGCGCCTTCGACGCGGCAGGTGTTGAAGTGATCA
ATCCCTGGGCGGCTTCGGCCGCATGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8901.08 Da        Isoelectric Point: 5.0348

>AT230898 WP_129517050.1 NZ_CP090484:3146064-3146306 [Burkholderia sp. S-53]
MDTAKIFKHGGSQAVRLPKDFRFETTEVRIRRHGASVILEPVPQDWAWLTPLIGPVDADFEAAATTQPAAQERPGLDVFE

Download         Length: 243 bp

>AT230898 NZ_CP125651:c654427-654173 [Rhizobium sp. BT04]
ATGCCCGCAGTCACAATCAGAAACCTCTCCGAAGCAACGCACCGTGCCCTCAAGGTGCGCGCGGCTCATCACGGGCGCAG
CGCCGAAGCGGAGATGCGAGAAATCCTCGAGGCTGCCGTCCGTCCAGAAACACGGCTGCGCCTTGGCAGTGTGCTCGCCG
AACGGAGCCGTCGCCTCGGCCTGACGAATGAGGACTTTGCCGTTCTGGATCAGGCTCGCGACAAGCTCCCTGCGAAGCCG
ATGAGCTTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References