Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | spoIISABC/SpoIISA-SpoIISB |
| Location | 1226468..1227385 | Replicon | chromosome |
| Accession | NZ_CP090477 | ||
| Organism | Bacillus amyloliquefaciens strain W0101 | ||
Toxin (Protein)
| Gene name | spoIISA | Uniprot ID | I2HQ15 |
| Locus tag | LXM91_RS06505 | Protein ID | WP_007407256.1 |
| Coordinates | 1226639..1227385 (-) | Length | 249 a.a. |
Antitoxin (Protein)
| Gene name | spoIISB | Uniprot ID | I2HQ14 |
| Locus tag | LXM91_RS06500 | Protein ID | WP_003154807.1 |
| Coordinates | 1226468..1226638 (-) | Length | 57 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LXM91_RS06460 (LXM91_06460) | 1221692..1223323 | + | 1632 | WP_015417294.1 | pyocin knob domain-containing protein | - |
| LXM91_RS06465 (LXM91_06465) | 1223336..1223707 | + | 372 | WP_015417295.1 | XkdW family protein | - |
| LXM91_RS06470 (LXM91_06470) | 1223712..1223909 | + | 198 | WP_012117366.1 | XkdX family protein | - |
| LXM91_RS06475 (LXM91_06475) | 1223966..1224727 | + | 762 | WP_033575307.1 | hypothetical protein | - |
| LXM91_RS06480 (LXM91_06480) | 1224779..1225042 | + | 264 | WP_003154815.1 | hemolysin XhlA family protein | - |
| LXM91_RS06485 (LXM91_06485) | 1225056..1225319 | + | 264 | WP_003154813.1 | phage holin | - |
| LXM91_RS06490 (LXM91_06490) | 1225333..1226199 | + | 867 | WP_039251757.1 | N-acetylmuramoyl-L-alanine amidase | - |
| LXM91_RS06500 (LXM91_06500) | 1226468..1226638 | - | 171 | WP_003154807.1 | type II toxin-antitoxin system SpoIISB family antitoxin | Antitoxin |
| LXM91_RS06505 (LXM91_06505) | 1226639..1227385 | - | 747 | WP_007407256.1 | type II toxin-antitoxin system SpoIISA family toxin | Toxin |
| LXM91_RS06510 (LXM91_06510) | 1227489..1228487 | - | 999 | WP_003154805.1 | inorganic phosphate transporter | - |
| LXM91_RS06515 (LXM91_06515) | 1228500..1229117 | - | 618 | WP_003154804.1 | DUF47 domain-containing protein | - |
| LXM91_RS06520 (LXM91_06520) | 1229403..1230719 | - | 1317 | WP_007610842.1 | amino acid permease | - |
| LXM91_RS06525 (LXM91_06525) | 1231042..1231992 | + | 951 | WP_039251754.1 | ring-cleaving dioxygenase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1191954..1235575 | 43621 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 249 a.a. Molecular weight: 29077.57 Da Isoelectric Point: 4.7755
>T230885 WP_007407256.1 NZ_CP090477:c1227385-1226639 [Bacillus amyloliquefaciens]
MLLFFQIMVWTMAAALILYVYASWRYEAKVKEKMFAIRKTWYLLFVLGSMVYWTYDPESLFAAWRQYLIVAVCFALIDAF
IFLSAYIKKLAGNELETDTREILEENNEMLHSYLEKLKTYQYLLKNEPIHVYYGSTEAYAEGISRLLAAYAEKMNVTASL
CDYSAQSDKDRLTEHMPDAADVQSRLNRKDVYYDQKGRLVLIPFTVQNRHYVIKLTSENLLTEFDYLLFTSLTSIYDLML
PIEEEGDG
MLLFFQIMVWTMAAALILYVYASWRYEAKVKEKMFAIRKTWYLLFVLGSMVYWTYDPESLFAAWRQYLIVAVCFALIDAF
IFLSAYIKKLAGNELETDTREILEENNEMLHSYLEKLKTYQYLLKNEPIHVYYGSTEAYAEGISRLLAAYAEKMNVTASL
CDYSAQSDKDRLTEHMPDAADVQSRLNRKDVYYDQKGRLVLIPFTVQNRHYVIKLTSENLLTEFDYLLFTSLTSIYDLML
PIEEEGDG
Download Length: 747 bp
>T230885 NZ_CP125637:c1085766-1085338 [Rhizobium leguminosarum]
GTGAGACTTCTGCTGGACACGAATGTGCTTTCCGAGGTGACAAGGCCGCGTCCCGATGCACATGTCCTACAATGGCTGGA
CAGTCTCGACGAGGATCGCTCATTCATCAGCGTCGTATCGATCGCGGAGATCCGGCGTGGTGTTGCATTGATGGAAAGCG
GCCGGAAGCGCGACGCGCTGGCTGAATGGCTTGCCCAAGACCTGCCGCAGCGCTTCGAGCAGCGTGTCATCCCTGTGGAT
CAGCCGGTTGCGATAGCTTGGGGCGACTTGATGGGGCTCGCAAAGCGAAGCGGGCGCGGCTTGTCGTCAATGGATGGCCT
GATTGCCGCCACCGCGATTGCTCACGATCTCACCCTCGCCACTCGCAATATAAAGGATTTCGAGGGCTTTGAGATCGAGC
TTGTCGACCCTTGGACCGAGCGCCCGTGA
GTGAGACTTCTGCTGGACACGAATGTGCTTTCCGAGGTGACAAGGCCGCGTCCCGATGCACATGTCCTACAATGGCTGGA
CAGTCTCGACGAGGATCGCTCATTCATCAGCGTCGTATCGATCGCGGAGATCCGGCGTGGTGTTGCATTGATGGAAAGCG
GCCGGAAGCGCGACGCGCTGGCTGAATGGCTTGCCCAAGACCTGCCGCAGCGCTTCGAGCAGCGTGTCATCCCTGTGGAT
CAGCCGGTTGCGATAGCTTGGGGCGACTTGATGGGGCTCGCAAAGCGAAGCGGGCGCGGCTTGTCGTCAATGGATGGCCT
GATTGCCGCCACCGCGATTGCTCACGATCTCACCCTCGCCACTCGCAATATAAAGGATTTCGAGGGCTTTGAGATCGAGC
TTGTCGACCCTTGGACCGAGCGCCCGTGA
Antitoxin
Download Length: 57 a.a. Molecular weight: 6676.74 Da Isoelectric Point: 10.9273
>AT230885 WP_003154807.1 NZ_CP090477:c1226638-1226468 [Bacillus amyloliquefaciens]
MEQAFQNGQPEQRAKPFKMFKKRSMTSIASYQVSPHTARIFKENERLIDKYKQKKA
MEQAFQNGQPEQRAKPFKMFKKRSMTSIASYQVSPHTARIFKENERLIDKYKQKKA
Download Length: 171 bp
>AT230885 NZ_CP125637:c1086029-1085763 [Rhizobium leguminosarum]
ATGCAGCCATCACGACCAGAGGATAAAAGTTGGACCGTCGCCAGTGCGAAGGCCAAGCTGTCTGAGGTTATCGAACGCGC
GCAAGCAACGCCGCAAACAATCATGCGCAATGGCAAACCAAGCGTCGTCGTCGTTTCGGCCGAGGAATGGCAGCGGAAGA
CCGCGCGCAAGGGCACCCTTGCAGAGTTTCTGATGCAATCGCCGCTGCGTGGCGCTGATCTGGACCTCGAACGGCAGCGC
GACGAACCGCGTGATCTTCAGCTGTGA
ATGCAGCCATCACGACCAGAGGATAAAAGTTGGACCGTCGCCAGTGCGAAGGCCAAGCTGTCTGAGGTTATCGAACGCGC
GCAAGCAACGCCGCAAACAATCATGCGCAATGGCAAACCAAGCGTCGTCGTCGTTTCGGCCGAGGAATGGCAGCGGAAGA
CCGCGCGCAAGGGCACCCTTGCAGAGTTTCTGATGCAATCGCCGCTGCGTGGCGCTGATCTGGACCTCGAACGGCAGCGC
GACGAACCGCGTGATCTTCAGCTGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|