Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2107207..2107478 Replicon chromosome
Accession NZ_CP090456
Organism Escherichia coli strain B379

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2107337..2107440 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2107207..2107478 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZ684_RS10025 2103762..2104424 - 663 WP_234679345.1 exodeoxyribonuclease X -
LZ684_RS10030 2104448..2105104 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein YobB -
LZ684_RS10035 2105206..2105436 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LZ684_RS10040 2105575..2105949 + 375 WP_000168747.1 CopC domain-containing protein YobA -
LZ684_RS10045 2105953..2106825 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
LZ684_RS10050 2106838..2107179 + 342 WP_000976476.1 YebY family protein -
- 2107207..2107478 - 272 - - Antitoxin
- 2107337..2107440 + 104 - - Toxin
LZ684_RS10055 2107575..2108231 + 657 WP_000812720.1 protein-serine/threonine phosphatase -
LZ684_RS10060 2108232..2108423 - 192 WP_001296140.1 YebW family protein -
LZ684_RS10065 2108528..2108764 - 237 WP_001295499.1 YebV family protein -
LZ684_RS10070 2108882..2110321 - 1440 WP_024176540.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T230807 NZ_CP090456:2107337-2107440 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT230807 NZ_CP090456:c2107478-2107207 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References