Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 88781..89150 Replicon chromosome
Accession NZ_CP090441
Organism Xanthomonas arboricola strain YchA

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0B2CMD0
Locus tag LZZ50_RS00405 Protein ID WP_016904515.1
Coordinates 88781..88915 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID V7Z8F2
Locus tag LZZ50_RS00410 Protein ID WP_006451340.1
Coordinates 88998..89150 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZZ50_RS00390 (LZZ50_00390) 85848..86792 - 945 WP_245103655.1 MBL fold metallo-hydrolase -
LZZ50_RS00395 (LZZ50_00395) 86850..88139 - 1290 WP_245103657.1 tryptophan--tRNA ligase -
LZZ50_RS00400 (LZZ50_00400) 88321..88530 - 210 WP_016904514.1 CsbD family protein -
LZZ50_RS00405 (LZZ50_00405) 88781..88915 - 135 WP_016904515.1 entericidin A/B family lipoprotein Toxin
LZZ50_RS00410 (LZZ50_00410) 88998..89150 - 153 WP_006451340.1 entericidin A/B family lipoprotein Antitoxin
LZZ50_RS00415 (LZZ50_00415) 89260..90183 - 924 WP_026064823.1 arginase -
LZZ50_RS00420 (LZZ50_00420) 90666..91118 + 453 WP_046344911.1 roadblock/LC7 domain-containing protein -
LZZ50_RS00425 (LZZ50_00425) 91183..91542 + 360 WP_016904518.1 hypothetical protein -
LZZ50_RS00430 (LZZ50_00430) 91637..92554 + 918 WP_245103659.1 hypothetical protein -
LZZ50_RS00435 (LZZ50_00435) 92551..93093 + 543 WP_016904520.1 GTPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4443.26 Da        Isoelectric Point: 9.3487

>T230758 WP_016904515.1 NZ_CP090441:c88915-88781 [Xanthomonas arboricola]
MKRAIVLLVLSVLSVGMLSGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T230758 NZ_CP125351:c3760245-3759868 [Escherichia fergusonii]
ATGAAAACATTACCTGTATTACCCGGGCAGGCGGCCAGTTCTCGCCCGTCTCCTGTTGAAATCTGGCAGACACTGCTCAC
CCGACTGCTGGACCAGCACTATGGCCTTACGCTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCCGGCATTTCACTGTGCGATGCAGTGAACTTTCTTGTTGAAAAATACGCGCTGGTGCGTACCGACCAGCTGGAATTC
AGTGCCTGTACCCGCTCTCAGTTAATAAACAGCATCGATATCCTCCGAGCTCGCCGGGCGACTGGCCTGATGACCCGCGA
CAATTACCGAACGGTAAATAACATTACCCTGGGTAAGTATCAGGAGGCGAAACGATGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5168.11 Da        Isoelectric Point: 8.2782

>AT230758 WP_006451340.1 NZ_CP090441:c89150-88998 [Xanthomonas arboricola]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGEKVEKKADNCSDGKC

Download         Length: 153 bp

>AT230758 NZ_CP125351:c3760702-3760334 [Escherichia fergusonii]
GTGTCAGACACGTTCCATGAAACAAATTATCCCGACAACAACAACGATCGCCCCTGGTGGGGGCTACCCTGCACCGTGAC
GCCCTGTTTCGGGGCACGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCAGACCGCGCCGGTATCAGAGGCCGGT
TCAGCGACGCGGATGCGTACCACCTGGACCAGGCCTTTCCACTGCTGATGAAACAACTGGAGCTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTGACACTGTATGCGAAGGGGCTGACCTGTGAAGCCGACACCCTCGGCTCCTG
TGGTTACGTTTATCTGGCTGTTTATCCGACGCCCGAAATGAAAAATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0B2CMD0

Antitoxin

Source ID Structure
AlphaFold DB A0A2N7V051

References