Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 1901037..1901950 Replicon chromosome
Accession NZ_CP090438
Organism Vibrio maritimus strain BH16

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LY387_RS08685 Protein ID WP_234493764.1
Coordinates 1901037..1901507 (-) Length 157 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag LY387_RS08690 Protein ID WP_234493765.1
Coordinates 1901507..1901950 (-) Length 148 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LY387_RS08655 1896620..1897243 + 624 WP_234493760.1 OmpA family protein -
LY387_RS08660 1897366..1897725 + 360 WP_042475668.1 DUF2750 domain-containing protein -
LY387_RS08665 1897756..1898442 - 687 WP_042475666.1 7-cyano-7-deazaguanine synthase QueC -
LY387_RS08670 1898478..1899158 - 681 WP_234493761.1 7-carboxy-7-deazaguanine synthase QueE -
LY387_RS08675 1899309..1900112 + 804 WP_234493762.1 Cof-type HAD-IIB family hydrolase -
LY387_RS08680 1900145..1901065 + 921 WP_234493763.1 lipid kinase YegS -
LY387_RS08685 1901037..1901507 - 471 WP_234493764.1 RES domain-containing protein Toxin
LY387_RS08690 1901507..1901950 - 444 WP_234493765.1 DUF2384 domain-containing protein Antitoxin
LY387_RS08695 1902074..1902982 - 909 WP_234493766.1 N-acetylglucosamine kinase -
LY387_RS08700 1903139..1903873 - 735 WP_234493767.1 tRNA-uridine aminocarboxypropyltransferase -
LY387_RS08705 1903949..1904749 + 801 WP_234493768.1 sterol desaturase family protein -
LY387_RS08710 1904746..1906785 - 2040 WP_234493769.1 methyl-accepting chemotaxis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-139)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(29-88)


Sequences

Toxin        


Download         Length: 157 a.a.        Molecular weight: 17921.26 Da        Isoelectric Point: 4.2560

>T230757 WP_234493764.1 NZ_CP090438:c1901507-1901037 [Vibrio maritimus]
MFLYRIVKKKFATNIEQVFDGEGARRYGGRWNSAGNRCVYLATSESLAILEVLVHLNDTELLNDYDLYRIDIDEALIIEL
DQGYLPDDWQEDPAPSSTAQIGDEWLESEMSLCLKIPSTIVPREFNCLLNLQHAAFNLEELEVVKLAFNPDHRLSR

Download         Length: 471 bp

>T230757 NZ_CP125351:3628652-3628870 [Escherichia fergusonii]
ATGTCCGATAAGCCTTTAACCAAAACTGATTATTTGATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAACGTGT
CATCGAAAAAAATAAATACGAACTCTCTGACAATGAACTGGCGGTATTTTATTCAGCAGCTGATCACCGTCTCGCTGAAT
TGACCATGAATAAACTTTACGACAAGATCCCCTCCTCCGTATGGAAATTCATTCGCTAA

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16507.73 Da        Isoelectric Point: 9.5612

>AT230757 WP_234493765.1 NZ_CP090438:c1901950-1901507 [Vibrio maritimus]
MTASTKFVPSQSTAGFWSQIGVPPRGRKLHEAIEAGFDYATYQKLANVTGIEKKELARITNIKSATLSRRAKDGKFSSEE
SDRLYRYAEVYNASLRLFEDDKLKAFQWMHNPVKALGYVAPSDMLKTSAETEEVLSVIGRLEHGVFN

Download         Length: 444 bp

>AT230757 NZ_CP125351:3628251-3628625 [Escherichia fergusonii]
ATGGACGAATACTCACCAAAACGACATGATATCGCACAGCTTAAATTTCTTTGCGAAACCCTGTATCATGACTGTCTTGC
AAATCTTGAAGAGAGCAACCATGGCTGGGTTAACGACCCAACCTCGGCTATCAATCTGCAGCTCAACGAACTGATTGAGC
ATATTGCAACCTTCGCACTTAATTACAAAATTAAGTATAATGAGGACAATAAGCTCATAGAGCAGATCGATGAATATCTG
GATGACACTTTTATGTTGTTCAGTAGTTATGGCATTAATACACAGGATTTACAGAAATGGCGAAAATCTGGAAACAGGCT
CTTCCGCTGTTTTGTTAACGCCACCAGGGCGAACCCTGTTAGTTTGTCGTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References