230731

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2012005..2012150 Replicon chromosome
Accession NZ_CP090432
Organism Klebsiella pneumoniae subsp. pneumoniae strain KPN857

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2012041..2012143 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2012005..2012150 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZ608_RS09865 (LZ608_09865) 2007135..2009195 + 2061 WP_004151449.1 oligopeptidase B -
LZ608_RS09870 (LZ608_09870) 2009199..2009858 - 660 WP_002911407.1 exodeoxyribonuclease X -
LZ608_RS09875 (LZ608_09875) 2009937..2010167 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LZ608_RS09880 (LZ608_09880) 2010280..2010654 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LZ608_RS09885 (LZ608_09885) 2010658..2011527 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
LZ608_RS09890 (LZ608_09890) 2011544..2011882 + 339 WP_002911404.1 YebY family protein -
- 2012005..2012150 - 146 - - Antitoxin
- 2012041..2012143 + 103 - - Toxin
LZ608_RS09895 (LZ608_09895) 2012518..2012661 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LZ608_RS09900 (LZ608_09900) 2012766..2013734 - 969 WP_004151446.1 VirK/YbjX family protein -
LZ608_RS09905 (LZ608_09905) 2013891..2014544 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LZ608_RS09910 (LZ608_09910) 2014541..2014732 - 192 WP_002911395.1 YebW family protein -
LZ608_RS09915 (LZ608_09915) 2014830..2015069 - 240 WP_002911393.1 YebV family protein -
LZ608_RS09920 (LZ608_09920) 2015185..2016618 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T230731 NZ_CP090432:2012041-2012143 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT230731 NZ_CP090432:c2012150-2012005 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References