Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1906985..1907130 Replicon chromosome
Accession NZ_CP090429
Organism Klebsiella pneumoniae strain DY1928

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1907021..1907123 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1906985..1907130 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LYZ32_RS09285 1902115..1904175 + 2061 WP_004151449.1 oligopeptidase B -
LYZ32_RS09290 1904179..1904838 - 660 WP_002911407.1 exodeoxyribonuclease X -
LYZ32_RS09295 1904917..1905147 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LYZ32_RS09300 1905260..1905634 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LYZ32_RS09305 1905638..1906507 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
LYZ32_RS09310 1906524..1906862 + 339 WP_016529031.1 YebY family protein -
- 1906985..1907130 - 146 - - Antitoxin
- 1907021..1907123 + 103 - - Toxin
LYZ32_RS09315 1907499..1907642 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LYZ32_RS09320 1907747..1908715 - 969 WP_074185275.1 VirK/YbjX family protein -
LYZ32_RS09325 1908872..1909525 + 654 WP_032447686.1 protein-serine/threonine phosphatase -
LYZ32_RS09330 1909522..1909713 - 192 WP_002911395.1 YebW family protein -
LYZ32_RS09335 1909811..1910050 - 240 WP_002911393.1 YebV family protein -
LYZ32_RS09340 1910166..1911599 - 1434 WP_032447684.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T230711 NZ_CP090429:1907021-1907123 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT230711 NZ_CP090429:c1907130-1906985 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References