Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2041799..2042067 Replicon chromosome
Accession NZ_CP090402
Organism Shigella sp. PIB

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2041926..2042029 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2041799..2042067 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LXH19_RS09735 2038352..2039014 - 663 WP_000944256.1 exodeoxyribonuclease X -
LXH19_RS09740 2039038..2039694 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein YobB -
LXH19_RS09745 2039796..2040026 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LXH19_RS09750 2040165..2040539 + 375 WP_001578488.1 CopC domain-containing protein YobA -
LXH19_RS09755 2040543..2041415 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
LXH19_RS09760 2041428..2041769 + 342 WP_000976485.1 YebY family protein -
- 2041799..2042067 - 269 - - Antitoxin
- 2041926..2042029 + 104 - - Toxin
LXH19_RS09765 2042164..2042820 + 657 WP_001559255.1 protein-serine/threonine phosphatase -
LXH19_RS09770 2042821..2043012 - 192 WP_001296140.1 YebW family protein -
LXH19_RS09775 2043117..2043353 - 237 WP_001295499.1 YebV family protein -
LXH19_RS09780 2043471..2044910 - 1440 WP_024186572.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2034487..2057907 23420


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T230658 NZ_CP090402:2041926-2042029 [Shigella sp. PIB]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT230658 NZ_CP090402:c2042067-2041799 [Shigella sp. PIB]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCTG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References