Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1906426..1906571 Replicon chromosome
Accession NZ_CP090397
Organism Klebsiella pneumoniae strain F4

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1906462..1906564 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1906426..1906571 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZG49_RS09200 1901556..1903616 + 2061 WP_004151449.1 oligopeptidase B -
LZG49_RS09205 1903620..1904279 - 660 WP_020324964.1 exodeoxyribonuclease X -
LZG49_RS09210 1904358..1904588 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LZG49_RS09215 1904701..1905075 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LZG49_RS09220 1905079..1905948 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
LZG49_RS09225 1905965..1906303 + 339 WP_002911404.1 YebY family protein -
- 1906426..1906571 - 146 - - Antitoxin
- 1906462..1906564 + 103 - - Toxin
LZG49_RS09230 1906940..1907083 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LZG49_RS09235 1907188..1908156 - 969 WP_004151446.1 VirK/YbjX family protein -
LZG49_RS09240 1908313..1908966 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LZG49_RS09245 1908963..1909154 - 192 WP_002911395.1 YebW family protein -
LZG49_RS09250 1909252..1909491 - 240 WP_002911393.1 YebV family protein -
LZG49_RS09255 1909607..1911040 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T230600 NZ_CP090397:1906462-1906564 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT230600 NZ_CP090397:c1906571-1906426 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References