Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1866923..1867068 Replicon chromosome
Accession NZ_CP090393
Organism Klebsiella pneumoniae strain YZH2429

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1866959..1867061 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1866923..1867068 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LY283_RS09060 1862053..1864113 + 2061 WP_004151449.1 oligopeptidase B -
LY283_RS09065 1864117..1864776 - 660 WP_002911407.1 exodeoxyribonuclease X -
LY283_RS09070 1864855..1865085 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LY283_RS09075 1865198..1865572 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LY283_RS09080 1865576..1866445 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
LY283_RS09085 1866462..1866800 + 339 WP_002911404.1 YebY family protein -
- 1866923..1867068 - 146 - - Antitoxin
- 1866959..1867061 + 103 - - Toxin
LY283_RS09090 1867436..1867579 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LY283_RS09095 1867684..1868652 - 969 WP_181834034.1 VirK/YbjX family protein -
LY283_RS09100 1868809..1869462 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LY283_RS09105 1869459..1869650 - 192 WP_002911395.1 YebW family protein -
LY283_RS09110 1869748..1869987 - 240 WP_002911393.1 YebV family protein -
LY283_RS09115 1870103..1871536 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T230578 NZ_CP090393:1866959-1867061 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT230578 NZ_CP090393:c1867068-1866923 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References