Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2745953..2746478 Replicon chromosome
Accession NZ_CP090382
Organism Acinetobacter towneri strain SCLZS30

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LZG54_RS13200 Protein ID WP_151421626.1
Coordinates 2745953..2746240 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LZG54_RS13205 Protein ID WP_072689757.1
Coordinates 2746230..2746478 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZG54_RS13175 (LZG54_13190) 2741993..2742910 + 918 Protein_2543 multicopper oxidase domain-containing protein -
LZG54_RS13180 (LZG54_13195) 2742897..2743817 + 921 WP_160242727.1 copper resistance protein B -
LZG54_RS13185 (LZG54_13200) 2743980..2744272 + 293 Protein_2545 transposase -
LZG54_RS13190 (LZG54_13205) 2744274..2744468 + 195 Protein_2546 DNA polymerase V -
LZG54_RS13195 (LZG54_13210) 2744484..2745788 + 1305 WP_234114183.1 Y-family DNA polymerase -
LZG54_RS13200 (LZG54_13215) 2745953..2746240 - 288 WP_151421626.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LZG54_RS13205 (LZG54_13220) 2746230..2746478 - 249 WP_072689757.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LZG54_RS13210 (LZG54_13225) 2746481..2746927 - 447 WP_234114184.1 hypothetical protein -
LZG54_RS13215 (LZG54_13230) 2747001..2747447 - 447 Protein_2551 recombinase family protein -
LZG54_RS13220 (LZG54_13235) 2747696..2747971 - 276 WP_234114185.1 DUF4268 domain-containing protein -
LZG54_RS13225 (LZG54_13240) 2747986..2748147 - 162 WP_234114186.1 DUF4268 domain-containing protein -
LZG54_RS13230 (LZG54_13245) 2748210..2749502 - 1293 WP_234114187.1 phospholipase D-like domain-containing protein -
LZG54_RS13235 (LZG54_13250) 2749538..2750263 - 726 Protein_2555 IS3-like element ISAba14 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2714613..2752705 38092


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11059.82 Da        Isoelectric Point: 10.0689

>T230536 WP_151421626.1 NZ_CP090382:c2746240-2745953 [Acinetobacter towneri]
MTYKLDFLEEALAEWNKLNPSIKQPLKKKLIKVLENPRIPKNNLSGHPNRYKIKLRSIGYRLVYEVIDDEVVVIVIAVGR
RENNAVYDDANSRHS

Download         Length: 288 bp

>T230536 NZ_CP124919:92012-92122 [Enterococcus faecalis]
GTGTTATTTGTGAAAGATTTAATGTCGTTGGTTATCGCACCGATCTTTGTAGGATTGGTTCTGGAAATGATTTCTCGTGT
GTTGGACGAGGAAGACGATAACCGAAAGTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9276.74 Da        Isoelectric Point: 5.0491

>AT230536 WP_072689757.1 NZ_CP090382:c2746478-2746230 [Acinetobacter towneri]
MTQLIHARMTASITELKKSPMDTVLAGKGEPVAILNRNTPAFYCVPADLYETMMEQLEDLELNKIADTRANQKRIRVNID
DL

Download         Length: 249 bp

>AT230536 NZ_CP124919:c92226-92162 [Enterococcus faecalis]
AACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGATTGCTTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References