230533

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 288558..288942 Replicon chromosome
Accession NZ_CP090382
Organism Acinetobacter towneri strain SCLZS30

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag LZG54_RS01350 Protein ID WP_234114370.1
Coordinates 288793..288942 (+) Length 50 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID N9CFL6
Locus tag LZG54_RS01345 Protein ID WP_004974509.1
Coordinates 288558..288800 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZG54_RS01325 (LZG54_01325) 284085..284480 + 396 WP_234114368.1 GtrA family protein -
LZG54_RS01330 (LZG54_01330) 284574..285779 + 1206 WP_225555585.1 FAD-binding oxidoreductase -
LZG54_RS01335 (LZG54_01335) 285783..286538 + 756 WP_225555584.1 SDR family NAD(P)-dependent oxidoreductase -
LZG54_RS01340 (LZG54_01340) 286600..288231 + 1632 WP_234114369.1 O-antigen ligase family protein -
LZG54_RS01345 (LZG54_01350) 288558..288800 + 243 WP_004974509.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
LZG54_RS01350 (LZG54_01355) 288793..288942 + 150 WP_234114370.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LZG54_RS01360 (LZG54_01365) 290538..291002 - 465 WP_131260631.1 bacterioferritin -
LZG54_RS01365 (LZG54_01370) 291250..291444 - 195 WP_131260630.1 bacterioferritin-associated ferredoxin -
LZG54_RS01370 (LZG54_01375) 291616..291999 - 384 WP_004809961.1 RidA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 282962..283987 1025


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-49)

Antitoxin

Antitoxin ParD

(1-64)


Sequences

Toxin        


Download         Length: 50 a.a.        Molecular weight: 5534.22 Da        Isoelectric Point: 4.2253

>T230533 WP_234114370.1 NZ_CP090382:288793-288942 [Acinetobacter towneri]
VYKLSNLAVDDFTAIYEYTLLNFGVAQADQYTQHLENTFHLLVSSPLIG

Download         Length: 150 bp

>T230533 NZ_CP124918:2807459-2807602 [Enterococcus faecalis]
ATGAATGTAAGTACTAAAATCTATGAAAGGAGAGGCCTTTTGTCTATCGCAGAAGCTTTAGCTCTGATGATTAGTTTCGG
TTCTTTTATCGCAACGTTAATCTTCGGAATCCTAGAGGCTGTAAAAGAAAACAATAAAAAATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8717.83 Da        Isoelectric Point: 8.6602

>AT230533 WP_004974509.1 NZ_CP090382:288558-288800 [Acinetobacter towneri]
MARTTSVTIGPQLDNFVSKLIESGRYGSTSEVMRSALRLLEQQENQTAALKQAIEAGENSGESTLSLKDIAAQVKQKHRV

Download         Length: 243 bp

>AT230533 NZ_CP124918:c2807361-2807163 [Enterococcus faecalis]
TTTTTAGGTAATTGTGCTATAATGGTAATGAAAAGAGAGCTATGCTGTAACATACCTCTCTGATGTAGAGCCGTTTAAGA
CGGTGACCTTTTTGATTATTTAAAAATAACCGTACTGGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATT
TCACAATCAGTGCAATCAAAGCAATGGTAAACATACCAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB N9CFL6

References