Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 1567194..1567731 Replicon chromosome
Accession NZ_CP090370
Organism Erythrobacter sp. SDW2

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag LY632_RS07670 Protein ID WP_234090560.1
Coordinates 1567194..1567487 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag LY632_RS07675 Protein ID WP_234090561.1
Coordinates 1567480..1567731 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LY632_RS07650 (LY632_07650) 1562981..1563691 - 711 WP_234090556.1 SDR family oxidoreductase -
LY632_RS07655 (LY632_07655) 1563843..1564223 + 381 WP_234090557.1 succinate dehydrogenase, cytochrome b556 subunit -
LY632_RS07660 (LY632_07660) 1564235..1564660 + 426 WP_234090558.1 succinate dehydrogenase, hydrophobic membrane anchor protein -
LY632_RS07665 (LY632_07665) 1564660..1566483 + 1824 WP_234090559.1 succinate dehydrogenase flavoprotein subunit -
LY632_RS07670 (LY632_07670) 1567194..1567487 - 294 WP_234090560.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LY632_RS07675 (LY632_07675) 1567480..1567731 - 252 WP_234090561.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
LY632_RS07680 (LY632_07680) 1567808..1569118 + 1311 WP_234090562.1 M20/M25/M40 family metallo-hydrolase -
LY632_RS07685 (LY632_07685) 1569268..1569642 + 375 WP_255695714.1 BlaI/MecI/CopY family transcriptional regulator -
LY632_RS07690 (LY632_07690) 1569639..1571276 + 1638 WP_234090563.1 M56 family metallopeptidase -
LY632_RS07695 (LY632_07695) 1571334..1572206 - 873 WP_234090564.1 neutral zinc metallopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-91)

Antitoxin

Antitoxin ParD

(3-75)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11109.70 Da        Isoelectric Point: 6.9890

>T230504 WP_234090560.1 NZ_CP090370:c1567487-1567194 [Erythrobacter sp. SDW2]
MHDVLVLPSAQADLDDIAIYTKEQWGRDQARRYLATMRSDITGLARFPRMHPAYESRHGSFRKMSSGEHLVFLLVNETTV
VVVRALHNRMDVEEALA

Download         Length: 294 bp

>T230504 NZ_CP124913:294337-294678 [Enterococcus faecalis]
ATGAATGTTGAAAAGAAGTACATTCCCAAAAAAGGAGATATTGTATGGATTGATTTTGATCCTGCTGCAGGTAAAGAAAT
TCAGAAGAGACGCCCTGGTTTAGTCGTGTCAAGATATGAATTTAATCGGAAAACCATGTTTGCTGTGATTTGCCCGATTA
CTTCCACCATTAAAAATATTCCCACTCGATATACGTTGCCCGATGACATAGAAACCCAAGGACAAGTAGTGATCTCACAA
CTGAAATCTTTGGACTTCACTGAAAGAAAATTAAGTCAAATTGAGCATTTGCCATTAAAAGATATGGCGAAAATTGACCA
AATAATTGAATATATTTTCTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9238.31 Da        Isoelectric Point: 5.8506

>AT230504 WP_234090561.1 NZ_CP090370:c1567731-1567480 [Erythrobacter sp. SDW2]
MTAKNTSIALGKPYTDFARRKVESGEFATTSEVVREAMRQYIAQDAKREALDRALKEGLDSGPARPFDWDAFMGRHFGPG
EDA

Download         Length: 252 bp

>AT230504 NZ_CP124913:294107-294337 [Enterococcus faecalis]
ATGCTAACAACTAAATCAAGAAGACAAGGAAGCTCGGTCGTTTTAACTTTACCCACTGATAATGGTAAAAAACCAAAAGT
CGACCAAGAATATATTGTGATGTATTCTGACGACGGTACAATTACATTAGTCCCTAAAATTCAGGATCCATTTAGTGAAG
GTCCAGAAGGTGAGTATTATGAAAAAGATGAGTGGCATGATCTTGCACCTGAGGGGAGAGAACTTTTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References