Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relB-parE/RHH(antitoxin) |
| Location | 2801794..2802347 | Replicon | chromosome |
| Accession | NZ_CP090366 | ||
| Organism | Stutzerimonas kunmingensis strain 7850S | ||
Toxin (Protein)
| Gene name | parE | Uniprot ID | - |
| Locus tag | LW136_RS13115 | Protein ID | WP_234173077.1 |
| Coordinates | 2801794..2802087 (-) | Length | 98 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A2W5CWX7 |
| Locus tag | LW136_RS13120 | Protein ID | WP_017940300.1 |
| Coordinates | 2802075..2802347 (-) | Length | 91 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LW136_RS13100 (LW136_13100) | 2797195..2799678 | + | 2484 | Protein_2574 | error-prone DNA polymerase | - |
| LW136_RS13105 (LW136_13105) | 2799741..2800062 | + | 322 | Protein_2575 | site-specific integrase | - |
| LW136_RS13110 (LW136_13110) | 2800391..2801800 | + | 1410 | WP_234173076.1 | site-specific integrase | - |
| LW136_RS13115 (LW136_13115) | 2801794..2802087 | - | 294 | WP_234173077.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LW136_RS13120 (LW136_13120) | 2802075..2802347 | - | 273 | WP_017940300.1 | CopG family ribbon-helix-helix protein | Antitoxin |
| LW136_RS13125 (LW136_13125) | 2802474..2802719 | - | 246 | WP_034021179.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| LW136_RS13130 (LW136_13130) | 2803160..2804182 | + | 1023 | WP_234173078.1 | restriction endonuclease | - |
| LW136_RS13135 (LW136_13135) | 2804330..2805268 | - | 939 | WP_234173079.1 | hypothetical protein | - |
| LW136_RS13140 (LW136_13140) | 2805875..2806702 | + | 828 | WP_003117867.1 | phosphonate ABC transporter ATP-binding protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | flank | IS/Tn | - | - | 2795667..2797037 | 1370 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 98 a.a. Molecular weight: 11169.64 Da Isoelectric Point: 5.9081
>T230503 WP_234173077.1 NZ_CP090366:c2802087-2801794 [Stutzerimonas kunmingensis]
VPRLIVTEGAAKGLERCRRFLSDKDPQIARRAAQAIERQFARLEESPEVGRPFPDLPELRELIIEFGDSGYVALYRYERA
DDTAYVLAFRHQKEAGY
VPRLIVTEGAAKGLERCRRFLSDKDPQIARRAAQAIERQFARLEESPEVGRPFPDLPELRELIIEFGDSGYVALYRYERA
DDTAYVLAFRHQKEAGY
Download Length: 294 bp
>T230503 NZ_CP124913:c289149-289006 [Enterococcus faecalis]
ATGAATGTAAGTACTAAAATCTATGAAAGGAGAGGCCTTTTGTCTATCGCAGAAGCTTTAGCTCTGATGATTAGTTTCGG
TTCTTTTATCGCAACGTTAATCTTCGGAATCCTAGAGGCTGTTAAAGAAGACAATAAAAAATAA
ATGAATGTAAGTACTAAAATCTATGAAAGGAGAGGCCTTTTGTCTATCGCAGAAGCTTTAGCTCTGATGATTAGTTTCGG
TTCTTTTATCGCAACGTTAATCTTCGGAATCCTAGAGGCTGTTAAAGAAGACAATAAAAAATAA
Antitoxin
Download Length: 91 a.a. Molecular weight: 10327.45 Da Isoelectric Point: 5.5751
>AT230503 WP_017940300.1 NZ_CP090366:c2802347-2802075 [Stutzerimonas kunmingensis]
MATSIKIDDDLKGRIQHLAGLRQRSSHWIMREAITQYVEREEARESFKQEALASWAAYQETGQHLTGQEARTWLGSWGTD
AEAELPKCHD
MATSIKIDDDLKGRIQHLAGLRQRSSHWIMREAITQYVEREEARESFKQEALASWAAYQETGQHLTGQEARTWLGSWGTD
AEAELPKCHD
Download Length: 273 bp
>AT230503 NZ_CP124913:c288862-288813 [Enterococcus faecalis]
AATAAAAATGCCCGAGCCTTAGAAAAATAAGAGGCTCGGGCATTTTTATT
AATAAAAATGCCCGAGCCTTAGAAAAATAAGAGGCTCGGGCATTTTTATT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|