Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 1140888..1141432 Replicon chromosome
Accession NZ_CP090365
Organism Photobacterium sp. TLY01

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LN341_RS20900 Protein ID WP_234205663.1
Coordinates 1140888..1141187 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LN341_RS20905 Protein ID WP_234205665.1
Coordinates 1141175..1141432 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LN341_RS20880 (LN341_20880) 1136617..1137516 + 900 WP_234205658.1 LysR family transcriptional regulator -
LN341_RS20885 (LN341_20885) 1137608..1138828 - 1221 WP_234205659.1 autotransporter outer membrane beta-barrel domain-containing protein -
LN341_RS20890 (LN341_20890) 1139117..1139476 + 360 WP_234205661.1 hypothetical protein -
LN341_RS20895 (LN341_20895) 1140125..1140676 - 552 WP_046221372.1 AAA family ATPase -
LN341_RS20900 (LN341_20900) 1140888..1141187 - 300 WP_234205663.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LN341_RS20905 (LN341_20905) 1141175..1141432 - 258 WP_234205665.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LN341_RS20910 (LN341_20910) 1141677..1142108 - 432 WP_234206614.1 GNAT family N-acetyltransferase -
LN341_RS20915 (LN341_20915) 1142218..1143380 + 1163 WP_234205667.1 IS3 family transposase -
LN341_RS20920 (LN341_20920) 1143679..1143974 - 296 Protein_1054 hypothetical protein -
LN341_RS20925 (LN341_20925) 1144140..1145609 - 1470 WP_234205669.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1140125..1149013 8888


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11814.77 Da        Isoelectric Point: 4.7493

>T230500 WP_234205663.1 NZ_CP090365:c1141187-1140888 [Photobacterium sp. TLY01]
MAEIIWTEPALSDLNEIAEYIALENTVAAKELVQTIFAKVERLETFPESGRVPPELDYLNYREIVINPCRIFYKYEAEKV
YILFVMRVERDLRRFLLRK

Download         Length: 300 bp

>T230500 NZ_CP124912:c12275-11853 [Enterococcus faecalis]
ATGGCGAATATTACTGACTTCACCGAAAAGCAATTTGAAGATCGTTTAGAAAAGAATGTTGAACGACTAACTAAAAATAG
ACTAGCGGTTGAATCGCCAACCGCTTTTTTACTTGGTGGGCAACCAGGGTCAGGGAAAACCAGTTTGCGATCAGCAATTT
TTGAAGAAACACAAGGGAATGTTATTGTCATTGATAATGATACCTTTAAACAACAGCACCCAAATTTTGACGAATTAGTG
AAACTCTATGAAAAAGACGTAGTAAAACACGTTACCCCTTATTCGAATCGCATGACAGAAGCACTTATTAGCCGTTTAAG
CGATCAAGGCTATAATTTAGTGATTGAAGGAACAGGACGAACAACAGACGTTCCCATTCAAACAGCCACAATGCTTCAAT
CTGGTTCTGTTGCAAAGTTTTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9564.02 Da        Isoelectric Point: 7.3180

>AT230500 WP_234205665.1 NZ_CP090365:c1141432-1141175 [Photobacterium sp. TLY01]
MKVELVTSLKRQATKILADLHETKEPVLITEHGKPSAYLVDVDDYEFMQNRLAILEGIARGERALADGKSVSHDGAKDRM
SKWLK

Download         Length: 258 bp

>AT230500 NZ_CP124912:c12549-12277 [Enterococcus faecalis]
ATGGCAGTTACGTATGAAAAAACATTTGAAATTGAAATCATTAATGAGTTATCGGCAAGTGTTTATAATCGGGTATTAAA
TTATGTTTTGAATCATGAACTAGATACTAAAAATACTCGTTTACTAGAAGTGAATCTTTTAAATCAATTAGAAGTGGCAC
AAGAAGTTGATTTATTTCAACAACCATTTGAAGAATTACAAGCTATTCATGAGTATTGGCGGTCAATGAATCAATATTCA
AAACAAATTTTGAATAAAGAGAAAGTGGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References