230497

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 266087..266994 Replicon plasmid unnamed
Accession NZ_CP090357
Organism Pantoea ananatis strain JBR-LB3-16

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LVR30_RS22490 Protein ID WP_019105827.1
Coordinates 266087..266554 (-) Length 156 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A8A4JZ23
Locus tag LVR30_RS22495 Protein ID WP_014598335.1
Coordinates 266551..266994 (-) Length 148 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LVR30_RS22470 (LVR30_22475) 261473..261706 - 234 WP_013027857.1 DUF333 domain-containing protein -
LVR30_RS22475 (LVR30_22480) 261794..262366 + 573 WP_014598338.1 NADPH-dependent FMN reductase -
LVR30_RS22480 (LVR30_22485) 262428..263363 - 936 WP_013027859.1 flagellin -
LVR30_RS22485 (LVR30_22490) 264048..265442 - 1395 WP_014604629.1 flagellar filament capping protein FliD -
LVR30_RS22490 (LVR30_22495) 266087..266554 - 468 WP_019105827.1 RES family NAD+ phosphorylase Toxin
LVR30_RS22495 (LVR30_22500) 266551..266994 - 444 WP_014598335.1 DUF2384 domain-containing protein Antitoxin
LVR30_RS22500 (LVR30_22505) 267380..267604 + 225 WP_013027863.1 KTSC domain-containing protein -
LVR30_RS22505 (LVR30_22510) 267758..268453 + 696 WP_210451087.1 hypothetical protein -
LVR30_RS22510 (LVR30_22515) 268529..269218 - 690 WP_014598333.1 HTH-type transcriptional regulator RutR -
LVR30_RS22515 (LVR30_22520) 269617..270708 + 1092 WP_013027866.1 pyrimidine utilization protein A -
LVR30_RS22520 (LVR30_22525) 270705..271457 + 753 WP_250331303.1 pyrimidine utilization protein B -
LVR30_RS22525 (LVR30_22530) 271483..271869 + 387 WP_013027868.1 pyrimidine utilization protein C -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - tssG / tssF / icmF/tssM / vgrG/tssI / clpV/tssH / hcp/tssD / dotU/tssL / vasE/tssK / vipB/tssC / vipA/tssB / fliC / fliC 1..338834 338834


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(2-145)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(31-89)


Sequences

Toxin        


Download         Length: 156 a.a.        Molecular weight: 17121.61 Da        Isoelectric Point: 5.7185

>T230497 WP_019105827.1 NZ_CP090357:c266554-266087 [Pantoea ananatis]
MKLYRMTKTRYLGSAWSGFGAREGGGRWNSVGVSMVYASETASLTMLETLIHLQSASVLDFFTLMSIDVPDRLIEWIDIK
QLPGDWAAPEAPAALRLFGDAWIQSGGSVALRVPSALSPVESNYLLNPEHPEFSAIVRQAVNIPFLFDARFSRQA

Download         Length: 468 bp

>T230497 NZ_CP124911:c2733092-2732991 [Enterococcus faecalis]
TTGTCAATCGAAGCGGCATTGGAATTGATGATTAGTTTTGCAGCGTTTGTTGCACTACTGATTTTCGGTATCCTTGAAGC
AACGAAAAACGATAAAAAATAA

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16375.69 Da        Isoelectric Point: 7.0208

>AT230497 WP_014598335.1 NZ_CP090357:c266994-266551 [Pantoea ananatis]
MKQFTLPVSAAEPDRLWQFAGLSSADGVMLMDQIDDGLDGTVASRIVTWAQISQAELRRMTGIAGSTFTRGVKSRFTAEQ
SERLVRFIRVMDRAVELFEGDKEKARQWLNEPARALGNKKPADLVASETGAYEVLKLITRLEHGVYS

Download         Length: 444 bp

>AT230497 NZ_CP124911:2732867-2733046 [Enterococcus faecalis]
TGAAAAGAGAGATATGCTACTACATACCTCTCCTTTATACCAACACCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGT
TTTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTTATTTTTTATCGTTTTTCGTTGCTTCAAGGATACC
GAAAATCAGTAGTGCAACAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References