Detailed information of TA system TA230494

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-MqsA
• Location: 3895419..3896154
• Replicon: chromosome
• Accession: NZ_CP090356
• Organism: Pantoea ananatis strain JBR-LB3-16

Toxin (Protein)

• Gene name: relE
• Uniprot ID: A0A8A4K8B1
• Locus tag: LVR30_RS18285
• Protein ID: WP_014605594.1
• Coordinates: 3895762..3896154 (-)
• Length: 131 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: LVR30_RS18280
• Protein ID: WP_013026116.1
• Coordinates: 3895419..3895772 (-)
• Length: 118 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LVR30_RS18240 (LVR30_18245)	3891718..3892404	+	687	WP_013026113.1	two-component system response regulator PmrA	-
LVR30_RS18245 (LVR30_18250)	3892401..3893468	+	1068	WP_128392053.1	two-component system sensor histidine kinase PmrB	-
LVR30_RS18250 (LVR30_18255)	3893831..3894370	+	540	WP_072138831.1	peptide-methionine (S)-S-oxide reductase MsrA	-
LVR30_RS18280 (LVR30_18285)	3895419..3895772	-	354	WP_013026116.1	type II toxin-antitoxin system MqsA family antitoxin	Antitoxin
LVR30_RS18285 (LVR30_18290)	3895762..3896154	-	393	WP_014605594.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
LVR30_RS18290 (LVR30_18295)	3896479..3897426	-	948	WP_015700094.1	sulfonate ABC transporter substrate-binding protein	-
LVR30_RS18295 (LVR30_18300)	3897521..3899407	-	1887	WP_164886564.1	aliphatic sulfonate ABC transporter substrate-binding protein	-
LVR30_RS18300 (LVR30_18305)	3899686..3900858	+	1173	WP_013026120.1	FMNH2-dependent alkanesulfonate monooxygenase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-2 (6-125)

Antitoxin

• Cro/C1-type helix-turn-helix domain (56-99)

Sequences

Toxin

Protein

• Length: 131 a.a.
• Molecular weight: 14987.27 Da
• Isoelectric Point: 10.1741

>T230494 WP_014605594.1 NZ_CP090356:c3896154-3895762 [Pantoea ananatis]
MGFTLYVHKRFDRVFKKTRLTDSVLCYAAGDVFTGVFEADLGGGVIKKRLALHQGKRGGARTVIFFRQGTNLVYYDGWVK
NLSRKYAREIDEDQLDTYRDVARMFFRANSEVMSLLVRSGMVREVKCNEN

Nucleotide

• Length: 393 bp

>T230494 NZ_CP124911:2567921-2568574 [Enterococcus faecalis]
TTGATTGGACTGTTGTTGGTGGATTTTATTAGTAAAGAACTCTATTTTGAAGCATTTAATTTTTCGAACGAATTAATAAA
AGAAGTATCTTACTACTCTTCCAAAAATATTGAACAAGTTAAATGCTTTGATATTGAAAAATATGTAAAAGAAGTTGAAG
ATGTTGAATTTGTTGAATACACGTTTCAAAAACAACTTAAAAGACGGATGCTTGGTTCAATCTCTAAAGTAGACGATGAA
GTCATTATAACAACAAACAAAGAATTAATGTTAGAACGAAAAAATTTCACTAAAATGCATGAGGTTATGCATTACTACAT
AGATATACCTAAAATTAATAATGCAACTCATACTTTTTCTGATATTCTTTTGAAAAATGGTTACTTGATGGAAGATTTTC
CAAAAGAATATCGTGCTAATGTCGGTGCTAGTATGTTAATGGCAAATGATCAAGCATTGTTTTACGCATTAAAAAAATTT
TATTCATTCGAAGAAATTGCACAATACTTTTTTATGAGCAAATCTGCATTAAGAAATAGACTCATCGAGCATCTTATGTA
TGTAAATAATTGTACTTTTGCACACGCTAATACACTTTTTAACAATTATTACTTTCATAAAGAAACTGATATCTACAGAT
TTATTTTCAATTAG

Antitoxin

Protein

• Length: 118 a.a.
• Molecular weight: 13097.13 Da
• Isoelectric Point: 6.4825

>AT230494 WP_013026116.1 NZ_CP090356:c3895772-3895419 [Pantoea ananatis]
MKTEPAELSELLEDAKAFHALGLATDEEVESIAKRAKNRELRARIASVKPMTATEIKDVRMRWGMSQSLVALSFGMTVDS
VSKWERGEITPSPPVMRMLQLLRDNGPELFTSKHEGI

Nucleotide

• Length: 354 bp

>AT230494 NZ_CP124911:2567541-2567924 [Enterococcus faecalis]
GTGCAACCATTAGCAAAAAGACTACAGCTTTTAAGAGAAGAAAAAGAATGGACAAAAACATATGTTGCAAAACAACTAGG
TTTAAATAACTTAGGAACCTATGCAAACTGGGAATATGGAACACGTGAACCAGATTCGGAAATGCTATCAAAAATTGCTT
CCTTATATGATGTATCTACCGATTTTTTACTAGGTAGAACAGAGGAAAGAATACATCTAAACGACAAGGAAAAAATTGGA
AAAAATATCATTTCTCATTTTCGTTTAAATACTTCTGATATGGACATAGAAGATATAGAAGAATTAGAAGAAGAATTAAT
CGACTTTCAAGATTTTCTTATAAAAAAAGCAAAAGAAAAAAAGGAACGTAACAAAAAAAATTGA