Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 4246623..4247103 Replicon chromosome
Accession NZ_CP090355
Organism Pseudomonas kribbensis strain H38E-23

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LXN51_RS19530 Protein ID WP_080770598.1
Coordinates 4246623..4246907 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0C1WGB2
Locus tag LXN51_RS19535 Protein ID WP_039767856.1
Coordinates 4246897..4247103 (-) Length 69 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LXN51_RS19490 (LXN51_19490) 4241866..4242339 + 474 WP_007956136.1 type II secretion system protein -
LXN51_RS19495 (LXN51_19495) 4242345..4242719 + 375 WP_011333435.1 type II secretion system protein -
LXN51_RS19500 (LXN51_19500) 4242694..4243245 + 552 WP_085704853.1 type II secretion system protein -
LXN51_RS19505 (LXN51_19505) 4243242..4243634 + 393 WP_085698595.1 curli production assembly/transport protein CsgE -
LXN51_RS19510 (LXN51_19510) 4243631..4244062 + 432 WP_007956141.1 curli assembly protein CsgF -
LXN51_RS19515 (LXN51_19515) 4244092..4244952 + 861 WP_085704855.1 CsgG/HfaB family protein -
LXN51_RS19520 (LXN51_19520) 4245837..4246217 + 381 WP_085704922.1 DUF6124 family protein -
LXN51_RS19525 (LXN51_19525) 4246291..4246482 + 192 WP_085698598.1 antitoxin -
LXN51_RS19530 (LXN51_19530) 4246623..4246907 - 285 WP_080770598.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LXN51_RS19535 (LXN51_19535) 4246897..4247103 - 207 WP_039767856.1 hypothetical protein Antitoxin
LXN51_RS19540 (LXN51_19540) 4247375..4248826 - 1452 WP_085704857.1 curlin -
LXN51_RS19545 (LXN51_19545) 4248853..4249317 - 465 WP_064595177.1 curlin -
LXN51_RS19550 (LXN51_19550) 4249411..4251645 - 2235 WP_085704859.1 Ig-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10918.75 Da        Isoelectric Point: 10.9931

>T230482 WP_080770598.1 NZ_CP090355:c4246907-4246623 [Pseudomonas kribbensis]
MQIKWRPKARVELSKILKYIGERNFVAATALHKSVVKTTSALPWHPHLYRKGRSPGTREIVVSPNYLVVYQVADRIEIVS
ILHARQEYPRRDPS

Download         Length: 285 bp

>T230482 NZ_CP124908:c2691583-2691440 [Enterococcus faecalis]
ATGAGCGTACTTCCAAAATTTACAGAAAGGAGAGGCCTGTTGTCAGCATATGAAACAATTCAGACGATCCTAGGGTTTGG
TATGTTTACCATTGCTTTGATTGCGCTGATTGTGAAATTGCTTAAAAATGACAATAAAAAATAA

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7570.49 Da        Isoelectric Point: 3.9012

>AT230482 WP_039767856.1 NZ_CP090355:c4247103-4246897 [Pseudomonas kribbensis]
MIDPSLIDPLCPVVSDLAPEEQAASYDRWFRAEVQASLDDPRPSIPHEQVMAEINALMESMRKSADAD

Download         Length: 207 bp

>AT230482 NZ_CP124908:2691321-2691507 [Enterococcus faecalis]
TGTGCTATAATGAAAACGAAAAGAGAGATATGCGTCAACATACCTCTCTGATGTAGAGCCGTTTAAGACGGTGACCGATT
TTGTTACAAAAAATAACCGTACTCGATCAAAGTAAACGGTTATTTTTTATTGTCATTTTTAAGCAATTTCACAATCAGCG
CAATCAAAGCAATGGTAAACATACCAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0C1WGB2

References