Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | FicTA/Fic(toxin) |
| Location | 503784..504472 | Replicon | chromosome |
| Accession | NZ_CP090316 | ||
| Organism | Xylella fastidiosa subsp. morus strain Riv16 | ||
Toxin (Protein)
| Gene name | VbhT | Uniprot ID | - |
| Locus tag | IUD23_RS02295 | Protein ID | WP_230577608.1 |
| Coordinates | 503969..504472 (+) | Length | 168 a.a. |
Antitoxin (Protein)
| Gene name | VbhA | Uniprot ID | A0A060HF63 |
| Locus tag | IUD23_RS02290 | Protein ID | WP_004087046.1 |
| Coordinates | 503784..503972 (+) | Length | 63 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IUD23_RS02245 (IUD23_02245) | 499262..500542 | - | 1281 | WP_234056388.1 | DUF2800 domain-containing protein | - |
| IUD23_RS02250 (IUD23_02250) | 500539..500970 | - | 432 | WP_234056258.1 | hypothetical protein | - |
| IUD23_RS02255 (IUD23_02255) | 501027..501221 | - | 195 | WP_016024078.1 | hypothetical protein | - |
| IUD23_RS02260 (IUD23_02260) | 501253..501444 | - | 192 | WP_040123260.1 | hypothetical protein | - |
| IUD23_RS02265 (IUD23_02265) | 501468..501659 | - | 192 | WP_004087232.1 | hypothetical protein | - |
| IUD23_RS02270 (IUD23_02270) | 501656..502063 | - | 408 | WP_038230230.1 | hypothetical protein | - |
| IUD23_RS02275 (IUD23_02275) | 502060..502530 | - | 471 | WP_038230232.1 | DUF1566 domain-containing protein | - |
| IUD23_RS02280 (IUD23_02280) | 502527..502952 | - | 426 | WP_038230234.1 | hypothetical protein | - |
| IUD23_RS02285 (IUD23_02285) | 502949..503404 | - | 456 | WP_038230236.1 | hypothetical protein | - |
| IUD23_RS02290 (IUD23_02290) | 503784..503972 | + | 189 | WP_004087046.1 | antitoxin VbhA family protein | Antitoxin |
| IUD23_RS02295 (IUD23_02295) | 503969..504472 | + | 504 | WP_230577608.1 | Fic/DOC family protein | Toxin |
| IUD23_RS02300 (IUD23_02300) | 504631..505305 | - | 675 | WP_038230238.1 | helix-turn-helix transcriptional regulator | - |
| IUD23_RS12175 | 505511..505636 | + | 126 | WP_267959509.1 | hypothetical protein | - |
| IUD23_RS02305 (IUD23_02305) | 505626..506123 | + | 498 | WP_234056389.1 | hypothetical protein | - |
| IUD23_RS02310 (IUD23_02310) | 506184..506372 | + | 189 | WP_038230241.1 | hypothetical protein | - |
| IUD23_RS02315 (IUD23_02315) | 506402..506617 | + | 216 | WP_230577607.1 | hypothetical protein | - |
| IUD23_RS02320 (IUD23_02320) | 506635..506856 | + | 222 | WP_234056390.1 | hypothetical protein | - |
| IUD23_RS02325 (IUD23_02325) | 506901..507482 | + | 582 | WP_038230245.1 | Bro-N domain-containing protein | - |
| IUD23_RS02330 (IUD23_02330) | 507548..508657 | + | 1110 | WP_040123376.1 | Bro-N domain-containing protein | - |
| IUD23_RS02335 (IUD23_02335) | 508654..508914 | + | 261 | WP_230577606.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 422869..537892 | 115023 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 168 a.a. Molecular weight: 19106.56 Da Isoelectric Point: 6.7262
>T230424 WP_230577608.1 NZ_CP090316:503969-504472 [Xylella fastidiosa subsp. morus]
MKYAGDRGDPYLDSETGVLRNLLGIRDQGWLDKIESTLSFLRTSELRERPVKGKFDLAHLQEIHNRLFQDVYDWAGQIRQ
VEISKGNTMFAQQIAIQSAAQQIFGQLAKERFLCGLDAEEFSKRAGDYLGEINVLHPFREGNGRTQREFIAQLAQRAGYR
IDWGVVS
MKYAGDRGDPYLDSETGVLRNLLGIRDQGWLDKIESTLSFLRTSELRERPVKGKFDLAHLQEIHNRLFQDVYDWAGQIRQ
VEISKGNTMFAQQIAIQSAAQQIFGQLAKERFLCGLDAEEFSKRAGDYLGEINVLHPFREGNGRTQREFIAQLAQRAGYR
IDWGVVS
Download Length: 504 bp
>T230424 NZ_CP124894:c2655465-2655364 [Enterococcus faecalis]
TTGTCAATCGAAGCGGCATTGGAATTGATGATTAGTTTTGCAGCGTTTGTTGCACTACTGATTTTCGGTATCCTTGAAGC
AACGAAAAACGATAAAAAATAA
TTGTCAATCGAAGCGGCATTGGAATTGATGATTAGTTTTGCAGCGTTTGTTGCACTACTGATTTTCGGTATCCTTGAAGC
AACGAAAAACGATAAAAAATAA
Antitoxin
Download Length: 63 a.a. Molecular weight: 6855.80 Da Isoelectric Point: 4.9859
>AT230424 WP_004087046.1 NZ_CP090316:503784-503972 [Xylella fastidiosa subsp. morus]
MLTDHEKAERRAVVQSALASQRIEGLEPDAQAVVDAECWARGEMTIAAAVDQYKARVRLQMA
MLTDHEKAERRAVVQSALASQRIEGLEPDAQAVVDAECWARGEMTIAAAVDQYKARVRLQMA
Download Length: 189 bp
>AT230424 NZ_CP124894:2655242-2655419 [Enterococcus faecalis]
AAAAGAGAGGTATGCGGGTACATACCTCTCTTTTATACCAACACCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTT
TTATTACTGTTTAACCGTTCGGCCTGTCAAGCTTATGAACGGTTATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGA
AAATCAGTAGTGCAACAA
AAAAGAGAGGTATGCGGGTACATACCTCTCTTTTATACCAACACCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTT
TTATTACTGTTTAACCGTTCGGCCTGTCAAGCTTATGAACGGTTATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGA
AAATCAGTAGTGCAACAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|