Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | spoIISABC/SpoIISA-SpoIISB |
| Location | 1386376..1387295 | Replicon | chromosome |
| Accession | NZ_CP090312 | ||
| Organism | Bacillus licheniformis strain NWMCC0046 | ||
Toxin (Protein)
| Gene name | spoIISA | Uniprot ID | - |
| Locus tag | LXN06_RS07035 | Protein ID | WP_154994986.1 |
| Coordinates | 1386549..1387295 (-) | Length | 249 a.a. |
Antitoxin (Protein)
| Gene name | spoIISB | Uniprot ID | A0A6C1W1Q1 |
| Locus tag | LXN06_RS07030 | Protein ID | WP_043925301.1 |
| Coordinates | 1386376..1386549 (-) | Length | 58 a.a. |
Genomic Context
Location: 1381803..1382900 (1098 bp)
Type: Others
Protein ID: WP_234112928.1
Type: Others
Protein ID: WP_234112928.1
Location: 1382876..1383724 (849 bp)
Type: Others
Protein ID: WP_234112930.1
Type: Others
Protein ID: WP_234112930.1
Location: 1383751..1384764 (1014 bp)
Type: Others
Protein ID: WP_234112932.1
Type: Others
Protein ID: WP_234112932.1
Location: 1384815..1386086 (1272 bp)
Type: Others
Protein ID: WP_154994984.1
Type: Others
Protein ID: WP_154994984.1
Location: 1389366..1391123 (1758 bp)
Type: Others
Protein ID: WP_154994988.1
Type: Others
Protein ID: WP_154994988.1
Location: 1391260..1391904 (645 bp)
Type: Others
Protein ID: WP_154994990.1
Type: Others
Protein ID: WP_154994990.1
Location: 1386149..1386280 (132 bp)
Type: Others
Protein ID: WP_003180875.1
Type: Others
Protein ID: WP_003180875.1
Location: 1386376..1386549 (174 bp)
Type: Antitoxin
Protein ID: WP_043925301.1
Type: Antitoxin
Protein ID: WP_043925301.1
Location: 1386549..1387295 (747 bp)
Type: Toxin
Protein ID: WP_154994986.1
Type: Toxin
Protein ID: WP_154994986.1
Location: 1387405..1388403 (999 bp)
Type: Others
Protein ID: WP_075753239.1
Type: Others
Protein ID: WP_075753239.1
Location: 1388416..1389033 (618 bp)
Type: Others
Protein ID: WP_003180884.1
Type: Others
Protein ID: WP_003180884.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LXN06_RS07005 (LXN06_07005) | 1381803..1382900 | + | 1098 | WP_234112928.1 | mannonate dehydratase | - |
| LXN06_RS07010 (LXN06_07010) | 1382876..1383724 | + | 849 | WP_234112930.1 | SDR family oxidoreductase | - |
| LXN06_RS07015 (LXN06_07015) | 1383751..1384764 | + | 1014 | WP_234112932.1 | zinc-binding alcohol dehydrogenase family protein | - |
| LXN06_RS07020 (LXN06_07020) | 1384815..1386086 | + | 1272 | WP_154994984.1 | MFS transporter | - |
| LXN06_RS07025 (LXN06_07025) | 1386149..1386280 | - | 132 | WP_003180875.1 | hypothetical protein | - |
| LXN06_RS07030 (LXN06_07030) | 1386376..1386549 | - | 174 | WP_043925301.1 | type II toxin-antitoxin system SpoIISB family antitoxin | Antitoxin |
| LXN06_RS07035 (LXN06_07035) | 1386549..1387295 | - | 747 | WP_154994986.1 | type II toxin-antitoxin system SpoIISA family toxin | Toxin |
| LXN06_RS07040 (LXN06_07040) | 1387405..1388403 | - | 999 | WP_075753239.1 | inorganic phosphate transporter | - |
| LXN06_RS07045 (LXN06_07045) | 1388416..1389033 | - | 618 | WP_003180884.1 | DUF47 domain-containing protein | - |
| LXN06_RS07050 (LXN06_07050) | 1389366..1391123 | + | 1758 | WP_154994988.1 | gamma-glutamyltransferase | - |
| LXN06_RS07055 (LXN06_07055) | 1391260..1391904 | + | 645 | WP_154994990.1 | YesL family protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 249 a.a. Molecular weight: 29398.84 Da Isoelectric Point: 4.5417
>T230421 WP_154994986.1 NZ_CP090312:c1387295-1386549 [Bacillus licheniformis]
MLLFYQFLVWLIVLALSLYVAAVWCFEKKLTEKTVAIRKTWYLLYVIGAVIYWTHDPQSIFTNPLHYLIVAVFFTLTDAF
IFLNAYFKKLGSSELATDTRMLLEENNDLLHTYQNRLKTFQYLLKNEPIHIYYGNIEAYAEGIEKLIKRFAEKMNISAAL
CEYNSEESKDHLLEHMENRFDVQEKLERKDVYYEENGKMVLIPFSIHDFDYVMKLTSEDLVTEFDYLLFTSLTSIYDLLL
PNEEEGDD
MLLFYQFLVWLIVLALSLYVAAVWCFEKKLTEKTVAIRKTWYLLYVIGAVIYWTHDPQSIFTNPLHYLIVAVFFTLTDAF
IFLNAYFKKLGSSELATDTRMLLEENNDLLHTYQNRLKTFQYLLKNEPIHIYYGNIEAYAEGIEKLIKRFAEKMNISAAL
CEYNSEESKDHLLEHMENRFDVQEKLERKDVYYEENGKMVLIPFSIHDFDYVMKLTSEDLVTEFDYLLFTSLTSIYDLLL
PNEEEGDD
Download Length: 747 bp
>T230421 NZ_CP124894:c317829-317734 [Enterococcus faecalis]
ATGTACGAGATTGTCACAAAAATTCTTGTGCCTATTTTTGTCGGGATTGTCCTGAAACTTGTAACCATTTGGTTGGAAAA
ACAGAACGAGGAATAA
ATGTACGAGATTGTCACAAAAATTCTTGTGCCTATTTTTGTCGGGATTGTCCTGAAACTTGTAACCATTTGGTTGGAAAA
ACAGAACGAGGAATAA
Antitoxin
Download Length: 58 a.a. Molecular weight: 6917.03 Da Isoelectric Point: 10.8356
>AT230421 WP_043925301.1 NZ_CP090312:c1386549-1386376 [Bacillus licheniformis]
MEPAFQQDQESVKKRLAFKMFKKQSKTNIAKYEVSPHTERIFRQNERLIGEYKRKKA
MEPAFQQDQESVKKRLAFKMFKKQSKTNIAKYEVSPHTERIFRQNERLIGEYKRKKA
Download Length: 174 bp
>AT230421 NZ_CP124894:317634-317699 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATCAGTAGTAGGGTGTCTTTTTTT
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATCAGTAGTAGGGTGTCTTTTTTT
Structures
Toxin
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Source | ID | Structure |
|---|---|---|
| No matching records found | ||
Antitoxin
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Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A6C1W1Q1 |