Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 3100208..3100810 Replicon chromosome
Accession NC_011146
Organism Geobacter bemidjiensis Bem

Toxin (Protein)


Gene name relE Uniprot ID E1P6B8
Locus tag GBEM_RS13360 Protein ID WP_012531106.1
Coordinates 3100208..3100504 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID E1P6B9
Locus tag GBEM_RS13365 Protein ID WP_012531107.1
Coordinates 3100508..3100810 (+) Length 101 a.a.

Genomic Context

GBEM_RS13340GBEM_RS13345GBEM_RS13350GBEM_RS13355GBEM_RS13360GBEM_RS13365GBEM_RS21270GBEM_RS13375GBEM_RS13380
Location: 3095799..3096488 (690 bp)
Type: Others
Protein ID: WP_012531102.1
Location: 3096485..3097843 (1359 bp)
Type: Others
Protein ID: WP_012531103.1
Location: 3097892..3099130 (1239 bp)
Type: Others
Protein ID: WP_012531104.1
Location: 3099206..3099934 (729 bp)
Type: Others
Protein ID: WP_012531105.1
Location: 3100208..3100504 (297 bp)
Type: Toxin
Protein ID: WP_012531106.1
Location: 3100508..3100810 (303 bp)
Type: Antitoxin
Protein ID: WP_012531107.1
Location: 3101264..3101767 (504 bp)
Type: Others
Protein ID: WP_148212916.1
Location: 3102273..3103598 (1326 bp)
Type: Others
Protein ID: WP_041263268.1
Location: 3103888..3105219 (1332 bp)
Type: Others
Protein ID: WP_041263270.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GBEM_RS133403095799..3096488+690WP_012531102.1response regulator transcription factor-
GBEM_RS133453096485..3097843+1359WP_012531103.1HAMP domain-containing protein-
GBEM_RS133503097892..3099130+1239WP_012531104.1cytochrome c-
GBEM_RS133553099206..3099934+729WP_012531105.1hypothetical protein-
GBEM_RS133603100208..3100504+297WP_012531106.1type II toxin-antitoxin system RelE/ParE family toxinToxin
GBEM_RS133653100508..3100810+303WP_012531107.1putative addiction module antidote proteinAntitoxin
GBEM_RS212703101264..3101767+504WP_148212916.1hypothetical protein-
GBEM_RS133753102273..3103598-1326WP_041263268.1hypothetical protein-
GBEM_RS133803103888..3105219-1332WP_041263270.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-94)

Antitoxin

Uncharacterized protein HI1420

(12-98)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11279.03 Da        Isoelectric Point: 9.9449

>T23036 WP_012531106.1 NC_011146:3100208-3100504 [Geobacter bemidjiensis Bem]
MYIVKTLPEFDAWLNGVKDRTTRLRLARRLDKVQRGNLGDVKPVGRGVFEMREFFGSGWRMYYVERDKVLIVMLGGGDKS
TQTADIAIALERADRLED

Download         Length: 297 bp

>T23036 NC_011146:3100208-3100504 [Geobacter bemidjiensis Bem]
ATGTATATCGTGAAAACGCTGCCTGAATTCGATGCCTGGTTAAATGGCGTCAAAGACCGCACCACTCGGTTGCGGCTGGC
TCGCCGCCTTGACAAGGTCCAGCGGGGCAATTTGGGTGACGTGAAACCTGTAGGCCGCGGCGTTTTTGAAATGCGTGAGT
TCTTTGGTTCCGGTTGGCGAATGTACTACGTGGAACGTGACAAAGTCCTTATCGTTATGCTCGGTGGTGGAGACAAATCC
ACACAAACAGCAGATATCGCCATCGCTTTGGAGCGGGCAGACAGATTGGAGGATTGA

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10706.41 Da        Isoelectric Point: 7.2778

>AT23036 WP_012531107.1 NC_011146:3100508-3100810 [Geobacter bemidjiensis Bem]
MPKKIVVSDLPEFDLATQLKNEADIAAYITMVIEEGDAAELAHALGVAARARGMAEIAQAAGLTREALYKALRPGAHPRF
DTISRVCSALGVRLVAQPRH

Download         Length: 303 bp

>AT23036 NC_011146:3100508-3100810 [Geobacter bemidjiensis Bem]
ATGCCGAAAAAAATCGTTGTATCCGACCTGCCGGAATTCGATCTTGCTACACAGCTAAAAAATGAAGCCGACATTGCCGC
GTACATCACCATGGTGATCGAAGAAGGTGACGCAGCAGAGTTGGCCCATGCTTTAGGAGTAGCCGCCCGAGCACGCGGCA
TGGCCGAAATTGCACAAGCTGCGGGGTTGACTAGGGAAGCGCTTTACAAAGCCCTACGTCCTGGAGCTCATCCACGCTTC
GACACGATCAGCAGAGTTTGTTCCGCGCTTGGAGTCCGCCTGGTTGCACAGCCTCGCCATTAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBE1P6B8

Antitoxin

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Source
ID
Structure
AlphaFold DBE1P6B9

References