Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 326127..326272 Replicon chromosome
Accession NZ_CP090242
Organism Klebsiella pneumoniae strain KPNSF-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 326163..326265 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 326127..326272 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LXH14_RS01365 321257..323317 + 2061 WP_004151449.1 oligopeptidase B -
LXH14_RS01370 323321..323980 - 660 WP_002911407.1 exodeoxyribonuclease X -
LXH14_RS01375 324059..324289 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LXH14_RS01380 324402..324776 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LXH14_RS01385 324780..325649 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
LXH14_RS01390 325666..326004 + 339 WP_002911404.1 YebY family protein -
- 326127..326272 - 146 - - Antitoxin
- 326163..326265 + 103 - - Toxin
LXH14_RS01395 326640..326783 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LXH14_RS01400 326888..327856 - 969 WP_014907334.1 VirK/YbjX family protein -
LXH14_RS01405 328013..328666 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LXH14_RS01410 328663..328854 - 192 WP_002911395.1 YebW family protein -
LXH14_RS01415 328952..329191 - 240 WP_002911393.1 YebV family protein -
LXH14_RS01420 329307..330740 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T230322 NZ_CP090242:326163-326265 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT230322 NZ_CP090242:c326272-326127 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References