Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1695980..1696125 Replicon chromosome
Accession NZ_CP090222
Organism Klebsiella pneumoniae strain BY11

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1696016..1696118 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1695980..1696125 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LVJ01_RS08385 1691110..1693170 + 2061 WP_004151449.1 oligopeptidase B -
LVJ01_RS08390 1693174..1693833 - 660 WP_043906809.1 exodeoxyribonuclease X -
LVJ01_RS08395 1693912..1694142 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LVJ01_RS08400 1694255..1694629 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LVJ01_RS08405 1694633..1695502 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
LVJ01_RS08410 1695519..1695857 + 339 WP_002911404.1 YebY family protein -
- 1695980..1696125 - 146 - - Antitoxin
- 1696016..1696118 + 103 - - Toxin
LVJ01_RS08415 1696494..1696637 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LVJ01_RS08420 1696742..1697710 - 969 WP_004151446.1 VirK/YbjX family protein -
LVJ01_RS08425 1697867..1698520 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LVJ01_RS08430 1698517..1698708 - 192 WP_002911395.1 YebW family protein -
LVJ01_RS08435 1698806..1699045 - 240 WP_002911393.1 YebV family protein -
LVJ01_RS08440 1699161..1700594 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1622925..1709196 86271


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T230306 NZ_CP090222:1696016-1696118 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT230306 NZ_CP090222:c1696125-1695980 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References