Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /RES-TIGR02293 |
| Location | 2295572..2296491 | Replicon | chromosome |
| Accession | NZ_CP090217 | ||
| Organism | Providencia rettgeri strain YK205 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | A0A1J0E7D4 |
| Locus tag | LVJ10_RS10325 | Protein ID | WP_042843809.1 |
| Coordinates | 2295572..2296033 (-) | Length | 154 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | LVJ10_RS10330 | Protein ID | WP_048607179.1 |
| Coordinates | 2296030..2296491 (-) | Length | 154 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LVJ10_RS10300 (LVJ10_10290) | 2291074..2292534 | + | 1461 | WP_042844339.1 | AMP nucleosidase | - |
| LVJ10_RS10305 (LVJ10_10295) | 2292551..2293084 | + | 534 | WP_226619150.1 | GNAT family N-acetyltransferase | - |
| LVJ10_RS10310 (LVJ10_10300) | 2293141..2293563 | + | 423 | WP_042843814.1 | helix-turn-helix domain-containing protein | - |
| LVJ10_RS10315 (LVJ10_10305) | 2293670..2294629 | + | 960 | WP_181469296.1 | acetyl-CoA carboxylase carboxyl transferase subunit alpha | - |
| LVJ10_RS10320 (LVJ10_10310) | 2294673..2295563 | + | 891 | WP_181469297.1 | LysR family transcriptional regulator | - |
| LVJ10_RS10325 (LVJ10_10315) | 2295572..2296033 | - | 462 | WP_042843809.1 | RES domain-containing protein | Toxin |
| LVJ10_RS10330 (LVJ10_10320) | 2296030..2296491 | - | 462 | WP_048607179.1 | DUF2384 domain-containing protein | Antitoxin |
| LVJ10_RS10335 (LVJ10_10325) | 2296581..2297048 | - | 468 | WP_042843807.1 | DUF1456 family protein | - |
| LVJ10_RS10340 (LVJ10_10330) | 2297234..2297548 | - | 315 | WP_042843806.1 | AzlD domain-containing protein | - |
| LVJ10_RS10345 (LVJ10_10335) | 2297545..2298246 | - | 702 | WP_048607181.1 | AzlC family ABC transporter permease | - |
| LVJ10_RS10350 (LVJ10_10340) | 2298933..2299574 | + | 642 | WP_048607183.1 | leucine efflux protein LeuE | - |
| LVJ10_RS10355 (LVJ10_10345) | 2299634..2300092 | - | 459 | WP_042843802.1 | GNAT family N-acetyltransferase | - |
| LVJ10_RS10360 (LVJ10_10350) | 2300511..2300897 | + | 387 | WP_048607185.1 | cytidine deaminase | - |
| LVJ10_RS10365 (LVJ10_10355) | 2300921..2301385 | + | 465 | WP_042843800.1 | NUDIX domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 154 a.a. Molecular weight: 17499.99 Da Isoelectric Point: 6.4846
>T230280 WP_042843809.1 NZ_CP090217:c2296033-2295572 [Providencia rettgeri]
MILYRLIKSDFAHDAWSGQGARLYGGRWNHKGTPAIYTSTSISLAALEILVHINQDTVLNHFTLLSIEINDRYVMKLSVE
HLPDDWQRDPAPTSTMDIGTTWLTNQDSLALIVPSCIIPYEYNAIINPMHPQFQKVTQTIKPLDFAFDPRFNR
MILYRLIKSDFAHDAWSGQGARLYGGRWNHKGTPAIYTSTSISLAALEILVHINQDTVLNHFTLLSIEINDRYVMKLSVE
HLPDDWQRDPAPTSTMDIGTTWLTNQDSLALIVPSCIIPYEYNAIINPMHPQFQKVTQTIKPLDFAFDPRFNR
Download Length: 462 bp
>T230280 NZ_CP090217:c2296033-2295572 [Providencia rettgeri]
ATGATTTTATATCGTTTGATTAAATCTGACTTTGCTCATGATGCGTGGTCCGGTCAAGGTGCTAGGTTATACGGTGGGCG
CTGGAACCATAAAGGTACGCCCGCTATCTACACATCAACAAGTATTTCATTAGCTGCTTTAGAAATTCTCGTTCATATAA
ACCAAGATACCGTGCTTAATCATTTCACTTTATTATCAATTGAGATCAACGATAGGTATGTGATGAAGCTGTCAGTAGAG
CATCTCCCTGATGATTGGCAGCGTGACCCAGCACCTACCTCCACAATGGACATAGGCACAACCTGGTTAACGAACCAAGA
CAGCCTAGCCTTAATTGTCCCTTCTTGTATTATTCCTTATGAATATAATGCCATTATTAACCCTATGCACCCGCAATTTC
AAAAAGTGACCCAAACCATTAAGCCCCTCGACTTTGCTTTTGACCCACGATTTAACCGGTAG
ATGATTTTATATCGTTTGATTAAATCTGACTTTGCTCATGATGCGTGGTCCGGTCAAGGTGCTAGGTTATACGGTGGGCG
CTGGAACCATAAAGGTACGCCCGCTATCTACACATCAACAAGTATTTCATTAGCTGCTTTAGAAATTCTCGTTCATATAA
ACCAAGATACCGTGCTTAATCATTTCACTTTATTATCAATTGAGATCAACGATAGGTATGTGATGAAGCTGTCAGTAGAG
CATCTCCCTGATGATTGGCAGCGTGACCCAGCACCTACCTCCACAATGGACATAGGCACAACCTGGTTAACGAACCAAGA
CAGCCTAGCCTTAATTGTCCCTTCTTGTATTATTCCTTATGAATATAATGCCATTATTAACCCTATGCACCCGCAATTTC
AAAAAGTGACCCAAACCATTAAGCCCCTCGACTTTGCTTTTGACCCACGATTTAACCGGTAG
Antitoxin
Download Length: 154 a.a. Molecular weight: 17056.55 Da Isoelectric Point: 9.9812
>AT230280 WP_048607179.1 NZ_CP090217:c2296491-2296030 [Providencia rettgeri]
MRNYIPALPTQPATPPFKPLWRFAGLPAERGIELTHFLRQGLSVTVLDNIQEWSGISKSELLRISGINERNVARRRNAGQ
PLNADESERIARLVRVFDAAVRLFNGDKSMASDWLNHPVKGLGHTRPIELIATESGALEVIDLIGRIEHGVFS
MRNYIPALPTQPATPPFKPLWRFAGLPAERGIELTHFLRQGLSVTVLDNIQEWSGISKSELLRISGINERNVARRRNAGQ
PLNADESERIARLVRVFDAAVRLFNGDKSMASDWLNHPVKGLGHTRPIELIATESGALEVIDLIGRIEHGVFS
Download Length: 462 bp
>AT230280 NZ_CP090217:c2296491-2296030 [Providencia rettgeri]
ATGAGAAACTATATTCCAGCACTCCCAACCCAACCCGCCACGCCACCTTTTAAGCCCCTATGGCGCTTTGCTGGCCTACC
CGCAGAACGTGGTATCGAACTCACTCATTTCCTACGACAAGGTCTTTCCGTTACGGTGTTAGACAACATTCAAGAATGGT
CTGGCATCAGCAAATCTGAATTACTCCGTATTTCAGGTATTAATGAGCGCAATGTGGCAAGACGTAGAAATGCAGGTCAG
CCACTCAATGCCGATGAAAGTGAAAGAATTGCTCGCTTAGTGCGTGTATTTGATGCCGCTGTACGCTTATTCAATGGTGA
TAAGTCAATGGCAAGTGATTGGTTGAATCACCCCGTGAAAGGCTTAGGACATACGCGCCCTATAGAGTTGATTGCCACTG
AAAGTGGTGCTCTTGAAGTTATCGACCTTATTGGCCGCATTGAACACGGTGTTTTTTCATGA
ATGAGAAACTATATTCCAGCACTCCCAACCCAACCCGCCACGCCACCTTTTAAGCCCCTATGGCGCTTTGCTGGCCTACC
CGCAGAACGTGGTATCGAACTCACTCATTTCCTACGACAAGGTCTTTCCGTTACGGTGTTAGACAACATTCAAGAATGGT
CTGGCATCAGCAAATCTGAATTACTCCGTATTTCAGGTATTAATGAGCGCAATGTGGCAAGACGTAGAAATGCAGGTCAG
CCACTCAATGCCGATGAAAGTGAAAGAATTGCTCGCTTAGTGCGTGTATTTGATGCCGCTGTACGCTTATTCAATGGTGA
TAAGTCAATGGCAAGTGATTGGTTGAATCACCCCGTGAAAGGCTTAGGACATACGCGCCCTATAGAGTTGATTGCCACTG
AAAGTGGTGCTCTTGAAGTTATCGACCTTATTGGCCGCATTGAACACGGTGTTTTTTCATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|