Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 1777605..1778119 Replicon chromosome
Accession NZ_CP090217
Organism Providencia rettgeri strain YK205

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag LVJ10_RS07780 Protein ID WP_181469200.1
Coordinates 1777605..1777913 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag LVJ10_RS07785 Protein ID WP_072035164.1
Coordinates 1777913..1778119 (-) Length 69 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LVJ10_RS07750 (LVJ10_07740) 1773497..1774333 + 837 WP_042844279.1 CheR family methyltransferase -
LVJ10_RS07755 (LVJ10_07745) 1774333..1775400 + 1068 WP_042844278.1 chemotaxis response regulator protein-glutamate methylesterase -
LVJ10_RS07760 (LVJ10_07750) 1775440..1775832 + 393 WP_034782834.1 chemotaxis response regulator CheY -
LVJ10_RS07765 (LVJ10_07755) 1775857..1776495 + 639 WP_042844277.1 protein phosphatase CheZ -
LVJ10_RS07770 (LVJ10_07760) 1776712..1777011 + 300 WP_042844276.1 helix-turn-helix transcriptional regulator -
LVJ10_RS07775 (LVJ10_07765) 1777032..1777589 - 558 WP_181469199.1 hypothetical protein -
LVJ10_RS07780 (LVJ10_07770) 1777605..1777913 - 309 WP_181469200.1 CcdB family protein Toxin
LVJ10_RS07785 (LVJ10_07775) 1777913..1778119 - 207 WP_072035164.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
LVJ10_RS07790 (LVJ10_07780) 1778318..1779469 + 1152 WP_048606786.1 flagellar biosynthesis protein FlhB -
LVJ10_RS07795 (LVJ10_07785) 1779462..1781561 + 2100 WP_042844272.1 flagellar biosynthesis protein FlhA -
LVJ10_RS07800 (LVJ10_07790) 1781932..1782372 - 441 WP_042844271.1 flagellar export chaperone FlgN -
LVJ10_RS07805 (LVJ10_07795) 1782382..1782684 - 303 WP_042844270.1 flagellar biosynthesis anti-sigma factor FlgM -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-101)

Antitoxin

Post-segregation antitoxin CcdA

(1-68)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11650.67 Da        Isoelectric Point: 6.0395

>T230279 WP_181469200.1 NZ_CP090217:c1777913-1777605 [Providencia rettgeri]
MQYCLYQNREDTVKHPYLLDIQSNIIDILNTLLVIPLFDSRLVKKPLPTCLNPQLFSNGQVFVLMTHQMACVPHSLLGTE
IVDLNCQQNTIKHAIDLLIDGF

Download         Length: 309 bp

>T230279 NZ_CP124824:c2589686-2588364 [Klebsiella pneumoniae]
ATGGCGACGCTTACCACCTGGATGAACAATGTGCGCGTGGGAACCTTAACCCGCCAGGCTAACGGGGCGCACAGTTTTCG
CTATGACGAAGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCACTGCCGCTGCAGTATGGCAATATCACTG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGACCGGATCGTCAGGCGCTATCAG
GCGCGCTCGAAGCAGCCGTTCGATCTGCTGGCCGAAGTCGGGCGGGATAGCGTAGGGGCGGTGACCCTCCTGCCGCCGGG
GGAAGAGGCGCACCTGGAAGGATTACGCTGGCAGACACTGGACGAGGCGCAGCTCACCGCTTTGCTGACCGCTTACCAGT
CGGATATCCCCCTCGGGATGATTACCGGCCAGGACGATTTCCGTATCTCGGTGGCCGGCGCCCAGGAGAAAACGGCGCTG
CTGCGGATGGGCGAGCAGTGGTGTATTCCGCAGGGCGCCACGCCGACCACGCATATCATTAAGCTGCCCATCGGCGAGAT
CAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAATGAGTATCTGTGCCTGGCGCTGGCCAGAGAACTGG
GCCTGGCGGTGCCGGAAGCGGAGATCATCGCCACCCCGCGGATCCGCGCCCTGGCGGTAACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGACGGGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCTTTTGGTCTTCCTTCAGCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCGAGTGAAGCGCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTCTTCCAGTGGCTGACGGGGGCGACGGACGGTCACGCAAAAAACTTCTCAATTTACCTGTTG
CCCGGCGGCAGCTACCACTTAACACCGTTCTACGACATTATTTCGGCGTTTCCGGTGCTGGGCGGCACGGGACTGCATCT
GCGCGATCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGTAAAACAGAGATTAACGCCATCTATCCGCGTCATT
TTCTGGCGACGGCCAAAGCGGTGAACTTTCCCCGGGAGCAGATGCTGGCGATCCTCCAGGAGTTTGCCGGGCATGTGCCG
CAGGCAATCGAAAGCGCTCGCCGGACGCTGCCGGCGGACTTTTCCAGCCACGTCTGGCTGGCCATTACAGAGAACATGCT
GAAGCTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGCTATAG

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7842.93 Da        Isoelectric Point: 6.2432

>AT230279 WP_072035164.1 NZ_CP090217:c1778119-1777913 [Providencia rettgeri]
ISVTVTPELCEQAWRAKLNLSAILTCALQAELKRLEAQKWKNENIEGFNQLNRNNEEYGLLSDKYKGF

Download         Length: 207 bp

>AT230279 NZ_CP124824:c2589952-2589686 [Klebsiella pneumoniae]
ATGAATTCCCCGCAGATATACAGTCCCGTGCAGCTGGCCAATTACCTGAAGCTGCTGCGCCAGCAGAACCACTGGACCCA
GGATGCGCTGGCCAGGCGGATCGGCATTAAGCAGGCCACGCTGTCCAATTTTGAAAATCACCCCGACAAAACCACCTTAA
CCACGCTGTTTAAGATCCTCCAGTCGCTGGGGGTGGTGATGACGCTGAACGCCAAAGCTGCTGAGACGGCGCCGGCTCCC
GATAACAACACGGACCTTGACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References