Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 473576..474111 Replicon plasmid unnamed1
Accession NZ_CP090208
Organism Pantoea agglomerans strain HJS002

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LZU96_RS22005 Protein ID WP_233988710.1
Coordinates 473824..474111 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LZU96_RS22000 Protein ID WP_233988709.1
Coordinates 473576..473827 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZU96_RS21980 (LZU96_21980) 469024..470223 + 1200 WP_233988706.1 MFS transporter -
LZU96_RS21985 (LZU96_21985) 470660..470872 + 213 WP_031374430.1 RNA chaperone/antiterminator CspA -
LZU96_RS21990 (LZU96_21990) 471288..472289 + 1002 WP_233988707.1 type I glyceraldehyde-3-phosphate dehydrogenase -
LZU96_RS21995 (LZU96_21995) 472327..473343 - 1017 WP_233988708.1 lipoate--protein ligase A -
LZU96_RS22000 (LZU96_22000) 473576..473827 + 252 WP_233988709.1 antitoxin Antitoxin
LZU96_RS22005 (LZU96_22005) 473824..474111 + 288 WP_233988710.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LZU96_RS22010 (LZU96_22010) 474350..475255 + 906 WP_233988711.1 DMT family transporter -
LZU96_RS22015 (LZU96_22015) 475418..476647 + 1230 WP_233988712.1 MFS transporter -
LZU96_RS22020 (LZU96_22020) 476671..477720 + 1050 WP_233988713.1 sugar phosphate isomerase/epimerase -
LZU96_RS22025 (LZU96_22025) 477804..478784 + 981 WP_233988714.1 LacI family DNA-binding transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - iroN 1..548340 548340


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11106.21 Da        Isoelectric Point: 10.4714

>T230251 WP_233988710.1 NZ_CP090208:473824-474111 [Pantoea agglomerans]
VTYTIKFREEALKEWLKLDKAIQQQFAKKLKKCCEHPHIPTAALRGLKDCYKIKLRASGFRLVYQVIDDQLIIAVVAVGK
RERSEVYNLASKRMR

Download         Length: 288 bp

>T230251 NZ_CP124819:110307-110558 [Escherichia coli]
ATGCGTACAATTAGTTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9233.49 Da        Isoelectric Point: 4.0780

>AT230251 WP_233988709.1 NZ_CP090208:473576-473827 [Pantoea agglomerans]
MPHIILSDTSASVSELKKNPMATVNAGEGYPVAILNRNQPAFYCVPAELYEQILDALDDSELVKLVNQRSQQKLIDVDLD
DFL

Download         Length: 252 bp

>AT230251 NZ_CP124819:110555-110809 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACACCATTTGAAGGTAAGGGGAAACCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACTGATGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References