Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 817108..817883 Replicon chromosome
Accession NZ_CP090207
Organism Pantoea agglomerans strain HJS002

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag LZU96_RS03990 Protein ID WP_233987157.1
Coordinates 817108..817593 (-) Length 162 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag LZU96_RS03995 Protein ID WP_233987158.1
Coordinates 817590..817883 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZU96_RS03965 (LZU96_03965) 812189..813220 + 1032 WP_233987152.1 ChuX/HutX family heme-like substrate-binding protein -
LZU96_RS03970 (LZU96_03970) 813217..814038 + 822 WP_233987153.1 ABC transporter substrate-binding protein -
LZU96_RS03975 (LZU96_03975) 814031..815029 + 999 WP_233987154.1 iron ABC transporter permease -
LZU96_RS03980 (LZU96_03980) 815026..815802 + 777 WP_233987155.1 heme ABC transporter ATP-binding protein -
LZU96_RS03985 (LZU96_03985) 815897..816394 + 498 WP_233987156.1 CinA family protein -
LZU96_RS03990 (LZU96_03990) 817108..817593 - 486 WP_233987157.1 GNAT family N-acetyltransferase Toxin
LZU96_RS03995 (LZU96_03995) 817590..817883 - 294 WP_233987158.1 DUF1778 domain-containing protein Antitoxin
LZU96_RS04000 (LZU96_04000) 818006..818989 - 984 WP_233987159.1 MDR family oxidoreductase -
LZU96_RS04005 (LZU96_04005) 819550..821703 + 2154 WP_233987160.1 ornithine decarboxylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(42-143)

Antitoxin

Vibrio phage ICP1, Orf50

(3-95)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 17473.46 Da        Isoelectric Point: 8.1621

>T230245 WP_233987157.1 NZ_CP090207:c817593-817108 [Pantoea agglomerans]
VISAPEPLHAGHILTPFCCGVDSMDNWLKQRAMKKQLSGASRTFVCCDDAKVMAYYSLASSAVTTNTAPGHFRRNMPDPI
PVVVLGRLAVDKSLHGKGVGRALMRDAGLRVIQVAETIGIRGMLVHALSDEAREFYLRVGFEPSPIDPMMLMVTLGDLVH
A

Download         Length: 486 bp

>T230245 NZ_CP124813:c2813814-2813711 [Citrobacter freundii]
GGCAGGGTAACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10992.63 Da        Isoelectric Point: 9.8590

>AT230245 WP_233987158.1 NZ_CP090207:c817883-817590 [Pantoea agglomerans]
MPATNSMAMKRETLNLRIKPAERELIDRAAKARGKNRTDFVLEAARAAAEEALIEQRIIMADPQAYQEFLTRLDQAPSPN
AALRKTMQTPAPWEQEK

Download         Length: 294 bp

>AT230245 NZ_CP124813:2813706-2813849 [Citrobacter freundii]
CACATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTT
GGCATTAATGCAGGCTAAGTTACCCTGCCATTTAAGAATAGATGACAGCGCCAGGTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References