Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 738081..738226 Replicon chromosome
Accession NZ_CP090203
Organism Klebsiella pneumoniae strain JNKPN26

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 738117..738219 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 738081..738226 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LXM99_RS03385 (LXM99_03385) 733211..735271 + 2061 WP_004151449.1 oligopeptidase B -
LXM99_RS03390 (LXM99_03390) 735275..735934 - 660 WP_002911407.1 exodeoxyribonuclease X -
LXM99_RS03395 (LXM99_03395) 736013..736243 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LXM99_RS03400 (LXM99_03400) 736356..736730 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LXM99_RS03405 (LXM99_03405) 736734..737603 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
LXM99_RS03410 (LXM99_03410) 737620..737958 + 339 WP_002911404.1 YebY family protein -
- 738081..738226 - 146 - - Antitoxin
- 738117..738219 + 103 - - Toxin
LXM99_RS03415 (LXM99_03415) 738594..738737 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LXM99_RS03420 (LXM99_03420) 738842..739810 - 969 WP_004151446.1 VirK/YbjX family protein -
LXM99_RS03425 (LXM99_03425) 739967..740620 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LXM99_RS03430 (LXM99_03430) 740617..740808 - 192 WP_002911395.1 YebW family protein -
LXM99_RS03435 (LXM99_03435) 740906..741145 - 240 WP_002911393.1 YebV family protein -
LXM99_RS03440 (LXM99_03440) 741261..742694 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T230215 NZ_CP090203:738117-738219 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT230215 NZ_CP090203:c738226-738081 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References