Detailed information of TA system TA230164

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 451561..452214
• Replicon: chromosome
• Accession: NZ_CP090182
• Organism: Acinetobacter baumannii strain AB1343

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: LXM98_RS02200
• Protein ID: WP_000607077.1
• Coordinates: 451825..452214 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: V5V966
• Locus tag: LXM98_RS02195
• Protein ID: WP_001288210.1
• Coordinates: 451561..451818 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LXM98_RS02175 (LXM98_02175)	447077..448084	+	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-
LXM98_RS02180 (LXM98_02180)	448103..448480	+	378	WP_001216380.1	50S ribosomal protein L17	-
LXM98_RS02185 (LXM98_02185)	448662..450152	+	1491	WP_000415125.1	NAD(P)/FAD-dependent oxidoreductase	-
LXM98_RS02190 (LXM98_02190)	450201..451373	-	1173	WP_001190542.1	acyl-CoA dehydrogenase family protein	-
LXM98_RS02195 (LXM98_02195)	451561..451818	+	258	WP_001288210.1	succinate dehydrogenase assembly factor 2	Antitoxin
LXM98_RS02200 (LXM98_02200)	451825..452214	+	390	WP_000607077.1	membrane protein	Toxin
LXM98_RS02205 (LXM98_02205)	452984..454069	+	1086	WP_000049106.1	hypothetical protein	-
LXM98_RS02210 (LXM98_02210)	454147..454713	+	567	WP_000651538.1	rhombosortase	-
LXM98_RS02215 (LXM98_02215)	454901..457096	+	2196	WP_001158906.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15552.88 Da
• Isoelectric Point: 10.4313

>T230164 WP_000607077.1 NZ_CP090182:451825-452214 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T230164 NZ_CP124740:c2115309-2114959 [Escherichia coli O157:H7 str. EDL933]
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GTGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTT
AATCAGGTGCGGATGATGGATCTACGCGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGATGAGGTGGTGGAAGAGGC
GTTATTACGCTTGCAGGCGGTGGTGGAATAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10318.77 Da
• Isoelectric Point: 4.6150

>AT230164 WP_001288210.1 NZ_CP090182:451561-451818 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT230164 NZ_CP124740:c2115554-2115303 [Escherichia coli O157:H7 str. EDL933]
ATGCGTATTACCATAAAAAGATGGGGGAACAGTGCAGGTATGGTCATTCCCAATATCGTAATGAAAGAACTTAACTTACA
GCCGGGGCAGAGCGTGGAAGTGCAGGTGAGCAACAACCAACTGATTCTGACACCCATCTCCAGGCGCTACTCGCTTGATG
AACTGCTGGCACAGTGTGACATGAACGCCGCGGAACTTAGCGAGCAGGATGTCTGGGGTAAATCCACCCCTGCGGGTGAC
GAAATATGGTAA

Structures

Antitoxin

• AlphaFold DB: A0A7U4BQM7