Detailed information of TA system TA230163

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 220252..220901
• Replicon: chromosome
• Accession: NZ_CP090180
• Organism: Acinetobacter johnsonii strain DJ-Red

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: LXM48_RS01130
• Protein ID: WP_234304465.1
• Coordinates: 220515..220901 (+)
• Length: 129 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: A0A380U7S7
• Locus tag: LXM48_RS01125
• Protein ID: WP_004691282.1
• Coordinates: 220252..220509 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LXM48_RS01105 (LXM48_01105)	215869..216234	+	366	WP_004691290.1	50S ribosomal protein L17	-
LXM48_RS01110 (LXM48_01110)	216430..217920	+	1491	WP_234304463.1	NAD(P)/FAD-dependent oxidoreductase	-
LXM48_RS01115 (LXM48_01115)	218060..218851	+	792	WP_114392663.1	alpha/beta hydrolase	-
LXM48_RS01120 (LXM48_01120)	218887..220059	-	1173	WP_234304464.1	acyl-CoA dehydrogenase family protein	-
LXM48_RS01125 (LXM48_01125)	220252..220509	+	258	WP_004691282.1	succinate dehydrogenase assembly factor 2	Antitoxin
LXM48_RS01130 (LXM48_01130)	220515..220901	+	387	WP_234304465.1	hypothetical protein	Toxin
LXM48_RS01135 (LXM48_01135)	221422..222459	+	1038	WP_125280250.1	hypothetical protein	-
LXM48_RS01140 (LXM48_01140)	222531..223103	+	573	WP_004691274.1	rhombosortase	-
LXM48_RS01145 (LXM48_01145)	223286..225568	+	2283	WP_234304466.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 129 a.a.
• Molecular weight: 15322.32 Da
• Isoelectric Point: 10.5476

>T230163 WP_234304465.1 NZ_CP090180:220515-220901 [Acinetobacter johnsonii]
MEHRHFQLKPSRLAYVFQLSIYAVLMLVLYQLLPFGLWLIALVAGFVLYLFFLRGPQHFQLQHLDGRDWSLSLQKQSNAQ
RVQISHIVDHRAYIVIYFQHFRAKPMLVWCEKLPITQWKALKILTKMQ

Nucleotide

• Length: 387 bp

>T230163 NZ_CP124740:1981843-1982184 [Escherichia coli O157:H7 str. EDL933]
ATGACTGATACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCAATTAACCGTGAGTTA
TGCGAGTCGTTACCCGGATTACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGCCA
CCGGCACGGTGGTAGATGTCAAAGTGATGGAAGGCTGTATTGTCCTCACCGCCCAACCACCCGCCGCCGCCGAGAGCGAA
CTGATGCAGTCGCTGCGCCAGGTGTGCAAGCTGTCGGCGCGTAAACAAAGGCAGGTGCAGGAGTTTATTGGGGTGATTGC
GGGTAAACAGAAAGTTGCCTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10152.62 Da
• Isoelectric Point: 4.7091

>AT230163 WP_004691282.1 NZ_CP090180:220252-220509 [Acinetobacter johnsonii]
MTEEMSLEERKVIYRARRGLKEIDVYFDPYVKNYYLQADSAEKAMFAALVEQEDPDLLDWFMEVSEPPHPEMKTLIQKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT230163 NZ_CP124740:c1981848-1981772 [Escherichia coli O157:H7 str. EDL933]
AGTCATAACTGCTATTCCCTATAAATAGTGATTGTGATTAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Structures

Antitoxin

• AlphaFold DB: A0A380U7S7