Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/YafN(antitoxin) |
| Location | 560011..560576 | Replicon | chromosome |
| Accession | NZ_CP090179 | ||
| Organism | Vibrio harveyi strain XH2145 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | A0A916ASF8 |
| Locus tag | LXG94_RS12745 | Protein ID | WP_005445239.1 |
| Coordinates | 560289..560576 (+) | Length | 96 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | U3BLE1 |
| Locus tag | LXG94_RS12740 | Protein ID | WP_000086647.1 |
| Coordinates | 560011..560292 (+) | Length | 94 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LXG94_RS12690 (LXG94_12690) | 555170..555799 | + | 630 | WP_038899610.1 | AbiV family abortive infection protein | - |
| LXG94_RS12695 (LXG94_12695) | 555948..556415 | + | 468 | WP_233921904.1 | DUF4476 domain-containing protein | - |
| LXG94_RS12700 (LXG94_12700) | 556580..557203 | + | 624 | WP_127891279.1 | hypothetical protein | - |
| LXG94_RS12705 (LXG94_12705) | 557361..557945 | + | 585 | WP_050567843.1 | hypothetical protein | - |
| LXG94_RS12710 (LXG94_12710) | 558089..558307 | + | 219 | WP_058649093.1 | hypothetical protein | - |
| LXG94_RS12715 (LXG94_12715) | 558317..558523 | + | 207 | WP_077681051.1 | KTSC domain-containing protein | - |
| LXG94_RS12720 (LXG94_12720) | 558548..558640 | + | 93 | WP_072612521.1 | DUF3265 domain-containing protein | - |
| LXG94_RS12725 (LXG94_12725) | 558680..559153 | + | 474 | WP_038899614.1 | hypothetical protein | - |
| LXG94_RS12730 (LXG94_12730) | 559168..559260 | + | 93 | WP_169800196.1 | DUF3265 domain-containing protein | - |
| LXG94_RS12735 (LXG94_12735) | 559308..559799 | + | 492 | WP_038899615.1 | hypothetical protein | - |
| LXG94_RS12740 (LXG94_12740) | 560011..560292 | + | 282 | WP_000086647.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| LXG94_RS12745 (LXG94_12745) | 560289..560576 | + | 288 | WP_005445239.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LXG94_RS12750 (LXG94_12750) | 560604..560696 | + | 93 | WP_086584933.1 | DUF3265 domain-containing protein | - |
| LXG94_RS12755 (LXG94_12755) | 560727..561359 | + | 633 | WP_038899616.1 | DUF4145 domain-containing protein | - |
| LXG94_RS12760 (LXG94_12760) | 561497..562156 | + | 660 | WP_038899617.1 | hypothetical protein | - |
| LXG94_RS12765 (LXG94_12765) | 562178..562270 | + | 93 | WP_193788548.1 | DUF3265 domain-containing protein | - |
| LXG94_RS12770 (LXG94_12770) | 562299..562874 | + | 576 | WP_038899618.1 | hypothetical protein | - |
| LXG94_RS12775 (LXG94_12775) | 562889..562981 | + | 93 | WP_193788549.1 | DUF3265 domain-containing protein | - |
| LXG94_RS12780 (LXG94_12780) | 563413..563505 | + | 93 | WP_079720568.1 | DUF3265 domain-containing protein | - |
| LXG94_RS12785 (LXG94_12785) | 563657..564469 | + | 813 | WP_227740482.1 | hypothetical protein | - |
| LXG94_RS12790 (LXG94_12790) | 564501..564593 | + | 93 | WP_072600976.1 | DUF3265 domain-containing protein | - |
| LXG94_RS12795 (LXG94_12795) | 564628..565071 | + | 444 | WP_012127694.1 | hypothetical protein | - |
| LXG94_RS12800 (LXG94_12800) | 565086..565178 | + | 93 | WP_193788550.1 | DUF3265 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 509766..632527 | 122761 | |
| - | inside | Integron | - | - | 508515..626933 | 118418 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 96 a.a. Molecular weight: 11031.70 Da Isoelectric Point: 5.1098
>T230158 WP_005445239.1 NZ_CP090179:560289-560576 [Vibrio harveyi]
MKVVWSPLALQKLGDAAEFISLDNPPAAERWVNEVFDKTELLGSMPEMGRFVPEMPHTNYREIIFGHYRIIYSLSHEIRV
LTVRNCRQILSEDDV
MKVVWSPLALQKLGDAAEFISLDNPPAAERWVNEVFDKTELLGSMPEMGRFVPEMPHTNYREIIFGHYRIIYSLSHEIRV
LTVRNCRQILSEDDV
Download Length: 288 bp
>T230158 NZ_CP124740:519127-519234 [Escherichia coli O157:H7 str. EDL933]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA
Antitoxin
Download Length: 94 a.a. Molecular weight: 10398.91 Da Isoelectric Point: 5.8650
>AT230158 WP_000086647.1 NZ_CP090179:560011-560292 [Vibrio harveyi]
MSRIHFDQDIQPLSEFRAGVASYIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRTAEAQLASGLGVSN
DDARAQVLGRIKK
MSRIHFDQDIQPLSEFRAGVASYIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRTAEAQLASGLGVSN
DDARAQVLGRIKK
Download Length: 282 bp
>AT230158 NZ_CP124740:c519074-519013 [Escherichia coli O157:H7 str. EDL933]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|