Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 98872..99436 Replicon plasmid unnamed8
Accession NZ_CP090160
Organism Roseivivax marinus strain TCYB24

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LVO79_RS21720 Protein ID WP_240094711.1
Coordinates 99158..99436 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LVO79_RS21715 Protein ID WP_240094653.1
Coordinates 98872..99165 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LVO79_RS21695 (LVO79_21695) 94313..95185 + 873 WP_240094652.1 ParB N-terminal domain-containing protein -
LVO79_RS21700 (LVO79_21700) 95298..96283 + 986 Protein_101 IS5 family transposase -
LVO79_RS21705 (LVO79_21705) 96590..97527 - 938 Protein_102 IS110 family transposase -
LVO79_RS21710 (LVO79_21710) 98035..98722 - 688 Protein_103 transposase -
LVO79_RS21715 (LVO79_21715) 98872..99165 + 294 WP_240094653.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LVO79_RS21720 (LVO79_21720) 99158..99436 + 279 WP_240094711.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LVO79_RS21725 (LVO79_21725) 99504..100729 + 1226 Protein_106 IS3 family transposase -
LVO79_RS21730 (LVO79_21730) 101287..101595 - 309 WP_240094654.1 thiamine pyrophosphate-dependent enzyme -
LVO79_RS21735 (LVO79_21735) 101734..102147 + 414 Protein_108 transposase -
LVO79_RS21740 (LVO79_21740) 103057..104040 - 984 WP_240094655.1 cytochrome c oxidase assembly protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..136103 136103
- inside IScluster/Tn - - 90220..100729 10509


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-59)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10477.95 Da        Isoelectric Point: 4.5257

>T230156 WP_240094711.1 NZ_CP090160:99158-99436 [Roseivivax marinus]
MPDLKWTAAASDDLNAIVDYIAEDDPGAALRLLDEIVEKVEELPENPKAFRRGRVDGTREFVVRANYVIVYSENPDLVRI
LRVLHAARMWPT

Download         Length: 279 bp

>T230156 NZ_CP124740:248733-248909 [Escherichia coli O157:H7 str. EDL933]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTAGCGAATGGCAGCAACCATTTGAAACTCAG
GTTTCATGGGAGGCGCAGTGTCATGCCGCGTCACCCCTGCGATGAGATTAAAGAACCATTGCGTAAAGCAATCCTGAAAC
AACTCGGTTTGAGTTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10580.88 Da        Isoelectric Point: 6.8802

>AT230156 WP_240094653.1 NZ_CP090160:98872-99165 [Roseivivax marinus]
MPSKTSMLHVRVDDQLKAEATEALSGVGLTLSDAVRILLTRVASEGGMPAGLTADPHAYDTWFRAKVHEALKDDRPNRSH
QDVIRDARARIESNSSA

Download         Length: 294 bp

>AT230156 NZ_CP124740:248955-249371 [Escherichia coli O157:H7 str. EDL933]
ATGCGTTATCCCGTCACTCTTACACCCGCGCCGGAAGGCGGTTATATGGTTTCTTTTGTGGATATCCCTGAAGCGTTGAC
GCAGGGCGAAACTGTCGCTGAAGCGATGGAAGCGGCAAAAGATGCTTTACTGACCGCATTTGATTTTTATTTTGAAGATA
ACGAGCTTATCCCTTTACCTTCGCCATTAAATAGTCATGATCACTTTATTGAAGTACCTTTGAGCGTCGCCTCTAAGGTA
TTGCTGTTAAATGCTTTTTTACAGTCAGAAATCACTCAGCAAGAGTTAGCCAGGCGAATTGGCAAACCTAAACAAGAGAT
TACTCGCCTATTTAACTTGCATCATGCGACAAAAATCGACGCAGTCCAGCTCGCGGCAAAGGCGCTTGGCAAAGAGTTAT
CGCTGGTGATGGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References