Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-Xre
Location 1213315..1214191 Replicon plasmid pNg7g1
Accession NZ_CP090096
Organism Neorhizobium galegae strain 7g

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LZK81_RS28465 Protein ID WP_233957349.1
Coordinates 1213315..1213830 (-) Length 172 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag LZK81_RS28470 Protein ID WP_233957350.1
Coordinates 1213823..1214191 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZK81_RS28435 (LZK81_28440) 1208582..1208917 - 336 WP_037084912.1 hypothetical protein -
LZK81_RS28440 (LZK81_28445) 1208904..1209269 - 366 WP_046605982.1 Rieske 2Fe-2S domain-containing protein -
LZK81_RS28445 (LZK81_28450) 1209364..1210170 + 807 WP_233957346.1 IclR family transcriptional regulator -
LZK81_RS28450 (LZK81_28455) 1210269..1210748 + 480 WP_233957347.1 MarR family transcriptional regulator -
LZK81_RS28455 (LZK81_28460) 1211020..1211421 - 402 WP_046605980.1 response regulator -
LZK81_RS28460 (LZK81_28465) 1211433..1213139 - 1707 WP_233957348.1 ATP-binding protein -
LZK81_RS28465 (LZK81_28470) 1213315..1213830 - 516 WP_233957349.1 RES domain-containing protein Toxin
LZK81_RS28470 (LZK81_28475) 1213823..1214191 - 369 WP_233957350.1 DUF2384 domain-containing protein Antitoxin
LZK81_RS28475 (LZK81_28480) 1214267..1214911 - 645 WP_233957351.1 SMC-Scp complex subunit ScpB -
LZK81_RS28480 (LZK81_28485) 1214914..1215864 - 951 WP_233957352.1 DUF1403 family protein -
LZK81_RS28485 (LZK81_28490) 1216175..1217704 + 1530 WP_233957353.1 carboxypeptidase -
LZK81_RS28490 (LZK81_28495) 1217826..1218548 + 723 WP_233957354.1 L,D-transpeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB 1..1254988 1254988


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(11-164)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(70-119)


Sequences

Toxin        


Download         Length: 172 a.a.        Molecular weight: 18738.25 Da        Isoelectric Point: 6.3263

>T230041 WP_233957349.1 NZ_CP090096:c1213830-1213315 [Neorhizobium galegae]
MPELASESGILWRAYVPRWAHAPLSGDGAARFGGRWNPVGAATIYAARELSTAWAEYNQGFVQHPALIAQLRLDGARLAD
LTNPEVLVGLGVDETIHRCEWRADLDAGRIPSTHLLAERLLHDGCDGLIYPSFMSPGGTCVTLWRWNGKDQPKLTVTDPD
GRLPKSPASWL

Download         Length: 516 bp

>T230041 NZ_CP124665:1642433-1643302 [Pseudomonas aeruginosa]
ATGAACATGGCGCAGACCCACACCCCCGTCCCGAACCTGCAACAGCGCTTTCCCGAGCGGCTGGTGCAACTGGCCGACGG
CGCCCAGCTGGCCATCCGCGAATGCGGCCAGGGCCCGGTGGTGGTGCTGTTGCACGGCATCGGTTCGGGCTCGGCGTCCT
GGCTGCATTGCGCCCAGCGCCTGGCCGCCGGCAATCGGGTGATCGCCTGGGACGCGCCGGGTTACGGCCTGTCCACGCCG
CTGCCGCCGGCCCGGCCCAAGGCCTGCGACTACGCCGCGTGCCTGGAGCTGCTGCTGGATGCGCTGGGCGTGGAGAGCTG
CCTGCTGGTGGGCCACTCCCTCGGCGCGCTGATGGCCACGGCCTACGCCGCCGGCATCGGCGCGGCGCGGGTGCGCCGCC
TGGTGCTGCTCAGCCCGGCGCGCGGCTACGGCGCCGCCGAGCTGCGCGACAGCGGCGCCCAGGTGCGCCGCCAGCGCCTG
GAGAACCTGGAGCGCTTCGGTATCGACGGCATGGCCAGCGAGCGCACCGCGCGCCTGCTCGGCCGCAACCCCAGCGAGGA
GGCCCTGGCCTGGGTGCGCTGGAACATGGCGCGGCTCAACCCCGAGGGCTACCGCCAGGCCGTCGAGCTGCTCTGCGGCG
ACGACCTGCTGGGCAACGGGCAGCCTGCCGCTCCTTGCGAGGTGCATTGCGGCGAGGACGACGGCATCACCACGCCCGAG
AGTTGCGGCGCCATCGCCCGCCAGCTCGGCGCGTCGTTCTCGTCGATTCCCGGGGCCGGCCACGCCAGCCCGATCGAACA
ACCCGAAGTGGTCGCAGGACGCATCGGCCACGCGCAACGCCTCTCTCTTGAAGGAACCGCCAATGGATAA

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 12985.08 Da        Isoelectric Point: 10.1736

>AT230041 WP_233957350.1 NZ_CP090096:c1214191-1213823 [Neorhizobium galegae]
MAHVFEIGAAAFREPQSALLSARRVSNLLGLTHAELAKLIGVARNTLTAKSGARKVDLALSPVVRILAMASEMAGDENRA
AIWFKHQPIPGWAGKTAYDLVGEGKADKVLAYLEAVRSGVYA

Download         Length: 369 bp

>AT230041 NZ_CP124665:1643295-1644128 [Pseudomonas aeruginosa]
ATGGATAAGTCAGACGATTCGCAAGACAAGTACATCGTGCCTGGCCTCGAACGCGGCCTGCTGCTGCTCTGCGAGTTCAG
CCGGAAGGACCGTACCCTGACGGCGCCGGAGTTGGCGCGGCGCCTGAAGCTGCCGCGCTCGACCATCTTCCGCCTGCTGA
CCACCCTGGAGGCCATGGGCTTCGTCACCCGCAACGGCAACGAGTACCGCCTGGGCATGGCGGTGTTGCGCCTGGGCTTC
GAGTACCTGGCCTCGCTGGAGCTGACCGAACTCGGCCAGCCGCTGCTGAACCGCCTGTGCGACGAGATCCGCTACCCCTG
CAACCTGGTGGTGCGCGACGGCCGTTCGATCGTCTACGTGGCCAAGGTTTCGCCGTCCACCCCGCTGAGCAGCTCGGTGA
ACGTCGGGACCCGGTTGCCGGCCCACGCCACGGTGCTCGGCCGCATCCTGCTGCAGGACCTGAGCCTGGGCGAGCTGCGC
GAGCTGTACCCGGAGGAGCAGCTGGAGCAGTTCTCGCCGAACACCCCGCGCAGCGTGCTGGAACTCTTCGACATGGTCCA
GGGCGACCGCCAGCGTGGCTTCGTCCAGGGCGAGGGGTTCTTCGAGGCGAGCATCTCCACCGTCGCGGCGCCGGTACGTG
ATCACAGCGGTCGCGTCATCGCGGCGATGGGGGCGACCATCGCCGCCGGGCATATCGACCCGGAACGCATCGAGGGACTG
GTCAGCCGGGTGCGCAGCAGCGCCGACGAGCTGTCGTACCTGCTCGACTACCGCGCCGACGGCCAGGACAACGTCACCCC
GATCTTCCGGAGTCGCCCGCATGAAACCGTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References