Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE-YafN |
| Location | 1903113..1903632 | Replicon | chromosome |
| Accession | NZ_CP090095 | ||
| Organism | Neorhizobium galegae strain 7g | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | LZK81_RS09545 | Protein ID | WP_046606249.1 |
| Coordinates | 1903351..1903632 (+) | Length | 94 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A068T5N6 |
| Locus tag | LZK81_RS09540 | Protein ID | WP_038542472.1 |
| Coordinates | 1903113..1903361 (+) | Length | 83 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LZK81_RS09520 (LZK81_09520) | 1899456..1900295 | - | 840 | WP_233956006.1 | helix-turn-helix transcriptional regulator | - |
| LZK81_RS09525 (LZK81_09525) | 1900394..1901281 | + | 888 | WP_233956007.1 | SDR family oxidoreductase | - |
| LZK81_RS09530 (LZK81_09530) | 1901294..1902097 | - | 804 | WP_046606247.1 | DNA repair protein RadC | - |
| LZK81_RS09535 (LZK81_09535) | 1902101..1902937 | - | 837 | WP_046606248.1 | type I methionyl aminopeptidase | - |
| LZK81_RS09540 (LZK81_09540) | 1903113..1903361 | + | 249 | WP_038542472.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| LZK81_RS09545 (LZK81_09545) | 1903351..1903632 | + | 282 | WP_046606249.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LZK81_RS09550 (LZK81_09550) | 1903608..1904336 | - | 729 | WP_233956008.1 | DNA/RNA nuclease SfsA | - |
| LZK81_RS09555 (LZK81_09555) | 1904349..1906196 | - | 1848 | WP_233956009.1 | class I poly(R)-hydroxyalkanoic acid synthase | - |
| LZK81_RS09560 (LZK81_09560) | 1906320..1906721 | + | 402 | WP_233956011.1 | hypothetical protein | - |
| LZK81_RS09565 (LZK81_09565) | 1906867..1908084 | + | 1218 | WP_046606252.1 | LL-diaminopimelate aminotransferase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 94 a.a. Molecular weight: 11058.93 Da Isoelectric Point: 10.7023
>T230036 WP_046606249.1 NZ_CP090095:1903351-1903632 [Neorhizobium galegae]
MSYELAFLDVALKEWRKLDSNIREQFKRKLTERLENPRVAAAQLYGSKNRYKIKLRVIGYRLVYEVRDTQLVVLVIAVGR
RDRDAVYKAAEKR
MSYELAFLDVALKEWRKLDSNIREQFKRKLTERLENPRVAAAQLYGSKNRYKIKLRVIGYRLVYEVRDTQLVVLVIAVGR
RDRDAVYKAAEKR
Download Length: 282 bp
>T230036 NZ_CP124664:c4516841-4516086 [Pseudomonas aeruginosa]
GTGAGCGAGATCTGGCGACAGTGCAAGGGTGAGCGGTATATCCGACCGCTCCAGGGGCGCCTGGTGCGGTTGGTGGAGAG
CCAGGAGCAGGTGGCGACCCTGCAATTGGTCGACACCCTGGAAGAACAGGCGTTGCTCGAGGAACTGCTCGAGTCGAGCA
AGCCGCCGGTGCCGGCGGATGCCGAGCCATTGCATTACCTGTTGAAGACCCCGTTCCGTTATCCGCCCTTGCGCTGGGGG
TCGCGGTTTGGCCGTCGCCACGAGCCAAGCCTGTTCTACGCCGCGTTGAAGCTGGAAACGGCCATGGCCGAAAGCGCGTA
TTACCGTTGCGTCCTGTGGAGTGGCATGGTGGTGCCGCCACCGAGCGGGAGGATTCTGTCCGAGCACGCTTCGTTCGAGG
CGGGCTGGAAGGTGGAGCGGGGAATCCGTCTGCAGGCGCCGCCTTTCTCCGATCACGAGGCTGCGCTGACCGACATCGCC
GACTACCGCGCTCCCCAGGAACTGGGAAGTGCCATGCGCAGCGCCGGGGTGCAGGCATTCGAATACCGTTCGGCGCGTTG
CCCGGAGCGCGGCTGCAATGTCGCCCTGTTCACGCCCGCGGCCTTCACCGAAAAGCGTCCTCGCAACCTGACGCCCTGGC
TGTGCGAAACCACGGCCGGTTACGTGGCCTTCAAGCCGGCGCATGTGCCGGGGTCGCCGAAAATCTTCTCCTGGGAGCTG
TTCCTGGTGGACGGAAAGTTGCCGCATCCGGCGTGA
GTGAGCGAGATCTGGCGACAGTGCAAGGGTGAGCGGTATATCCGACCGCTCCAGGGGCGCCTGGTGCGGTTGGTGGAGAG
CCAGGAGCAGGTGGCGACCCTGCAATTGGTCGACACCCTGGAAGAACAGGCGTTGCTCGAGGAACTGCTCGAGTCGAGCA
AGCCGCCGGTGCCGGCGGATGCCGAGCCATTGCATTACCTGTTGAAGACCCCGTTCCGTTATCCGCCCTTGCGCTGGGGG
TCGCGGTTTGGCCGTCGCCACGAGCCAAGCCTGTTCTACGCCGCGTTGAAGCTGGAAACGGCCATGGCCGAAAGCGCGTA
TTACCGTTGCGTCCTGTGGAGTGGCATGGTGGTGCCGCCACCGAGCGGGAGGATTCTGTCCGAGCACGCTTCGTTCGAGG
CGGGCTGGAAGGTGGAGCGGGGAATCCGTCTGCAGGCGCCGCCTTTCTCCGATCACGAGGCTGCGCTGACCGACATCGCC
GACTACCGCGCTCCCCAGGAACTGGGAAGTGCCATGCGCAGCGCCGGGGTGCAGGCATTCGAATACCGTTCGGCGCGTTG
CCCGGAGCGCGGCTGCAATGTCGCCCTGTTCACGCCCGCGGCCTTCACCGAAAAGCGTCCTCGCAACCTGACGCCCTGGC
TGTGCGAAACCACGGCCGGTTACGTGGCCTTCAAGCCGGCGCATGTGCCGGGGTCGCCGAAAATCTTCTCCTGGGAGCTG
TTCCTGGTGGACGGAAAGTTGCCGCATCCGGCGTGA
Antitoxin
Download Length: 83 a.a. Molecular weight: 8737.05 Da Isoelectric Point: 4.1225
>AT230036 WP_038542472.1 NZ_CP090095:1903113-1903361 [Neorhizobium galegae]
MVSIVLAEVTASVSELKRNPMGTVAAGDGAPVAILNRNEPAFYCVPAKAYEAMMDRLEDLELNALADSRAGETVIKVTLD
EL
MVSIVLAEVTASVSELKRNPMGTVAAGDGAPVAILNRNEPAFYCVPAKAYEAMMDRLEDLELNALADSRAGETVIKVTLD
EL
Download Length: 249 bp
>AT230036 NZ_CP124664:c4517344-4516976 [Pseudomonas aeruginosa]
ATGAGCGCTCTCATCAAGGAACGTCCCAGCGCCGATGCCGTCCTGGCCAAGGCCGTCCTGGCCGCGCGCGAGCAATTGGG
GCTGACGCAGCTCGAACTGGCCGGCATCGTCGGCGTCGATCGCAGCGCCATCAGCCGCTGGAAGACCCAGGGCCTGCGGG
TGGACAGCAAGACCGGCGAGCTGGCTCTGCTGCTGGTGCGAGTCTATCGCGCACTGTATGCCCTGTTCGGCGGGCAGCAG
GAGGACATGCGCCACTTCCTGCGCACTCCCAACCATCACCTGGCGGGCGAGCCGCTGGCACTGATGGGACAGGTGCAGGG
CCTGGTTCATGTGCTGGAATACCTCGATGCGATCCGCGGCAAGGTCTGA
ATGAGCGCTCTCATCAAGGAACGTCCCAGCGCCGATGCCGTCCTGGCCAAGGCCGTCCTGGCCGCGCGCGAGCAATTGGG
GCTGACGCAGCTCGAACTGGCCGGCATCGTCGGCGTCGATCGCAGCGCCATCAGCCGCTGGAAGACCCAGGGCCTGCGGG
TGGACAGCAAGACCGGCGAGCTGGCTCTGCTGCTGGTGCGAGTCTATCGCGCACTGTATGCCCTGTTCGGCGGGCAGCAG
GAGGACATGCGCCACTTCCTGCGCACTCCCAACCATCACCTGGCGGGCGAGCCGCTGGCACTGATGGGACAGGTGCAGGG
CCTGGTTCATGTGCTGGAATACCTCGATGCGATCCGCGGCAAGGTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|